B-cell epitopes of Sm autoantigens

Antinuclear Antibodies: Diagnostic Markers for Autoimmune Diseases and Probes for Cell Biology

1989 • 1,543 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus

2001 • 551 citations

Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus

1966 • 452 citations

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

1984 • 371 citations

Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases

1984 • 354 citations

The mosaic of autoimmunity

1989 • 292 citations

Antinuclear antibodies (ANAs): Diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity

1988 • 274 citations

Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.

1987 • 229 citations

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.

1987 • 203 citations

Cell Biology of the snRNP Particle

1990 • 163 citations

The use of immunoblotting and immunoprecipitation of (U) small nuclear ribonucleoproteins in the analysis of sera of patients with mixed connective tissue disease and systemic lupus erythematosus: A cross‐sectional, longitudinal study

1986 • 150 citations

20S small nuclear ribonucleoprotein U5 shows a surprisingly complex protein composition.

1989 • 148 citations

Molecular cloning of a cDNA encoding the human Sm-D autoantigen.

1988 • 133 citations

Stress proteins, arthritis, and autoimmunity

1989 • 113 citations

Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5

1990 • 105 citations

Primary Structure of Human Nuclear Ribonucleoprotein Particle C Proteins: Conservation of Sequence and Domain Structures in Heterogeneous Nuclear RNA, mRNA, and Pre-rRNA-Binding Proteins

1987 • 94 citations

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

1988 • 90 citations

Cloned human snRNP proteins B and B' differ only in their carboxy-terminal part.

1989 • 87 citations

Characterization of U small nuclear RNA-associated proteins.

1984 • 83 citations

Very long charge runs in systemic lupus erythematosus-associated autoantigens.

1991 • 78 citations

Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive B-cell epitopes.

1989 • 72 citations

Further characterization and subcellular localization of Sm and Ul ribonucleoprotein antigens

1985 • 71 citations

A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B′

1989 • 68 citations

Small nuclear RNA associated proteins: autoantigens in connective tissue diseases.

1989 • 65 citations

Isolation of intact Sm/RNP antigens from rabbit thymus.

1983 • 64 citations

Primary Structure of a Human Small Nuclear Ribonucleoprotein Polypeptide as Deduced by cDNA Analysis

1989 • 62 citations

Heterologous expression and epitope mapping of a human small nuclear ribonucleoprotein-associated Sm-B'/B autoantigen.

1990 • 62 citations

Murine lupus monoclonal antibodies define five epitopes on two different Sm polypeptides.

1986 • 61 citations

Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide.

1988 • 60 citations

Recognition of synthetic peptides of Sm-D autoantigen by lupus sera

1990 • 54 citations

Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.

1989 • 49 citations

cDNA sequence of the rat U snRNP-associated protein N: description of a potential Sm epitope.

1989 • 44 citations

Autoantibodies and Their Relation to Rheumatic Diseases

1986 • 43 citations

The complete primary structure of the human snRNP E protein

1988 • 42 citations

Epitope mapping of recombinant HeLa SmB and B' peptides obtained by the polymerase chain reaction.

1990 • 42 citations

Cross-reactivity of the subunit of the Sm ribonucleoprotein autoantigen with proline-rich polypeptides

1992 • 38 citations

Epitope patterns of Anti‐RNP antibodies in rheumatic diseases evidence for an antigen‐driven autoimmune response

1990 • 38 citations

Functions of U-snRNPs

1990 • 35 citations

Longitudinal analysis of antibodies to histones, Sm-D peptides and ubiquitin in the serum of patients with systemic lupus erythematosus, rheumatoid arthritis and tuberculosis.

1990 • 34 citations

A repeated proline-rich sequence in Sm B/B′ and N is a dominant epitope recognized by human and murine autoantibodies

1990 • 31 citations

The small nuclear ribonucleoproteins, SmB and B', are products of a single gene

1991 • 29 citations

Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities.

1989 • 28 citations

Detection and quantification of human anti‐Sm antibodies using synthetic peptide and recombinant SmB antigens

1991 • 27 citations

Isolation of cDNA clones encoding the human Sm B/B′auto‐immune antigen and specifically reacting with human anti‐Sm auto‐immune sera

1989 • 23 citations

Autoantibody production against the U small nuclear ribonucleoprotein particle proteins E, F and G in patients with connective tissue diseases

1990 • 22 citations

Regulated expression of the small nuclear ribonucleoprotein particle protein SmN in embryonic stem cell differentiation.

1990 • 20 citations

Expression of the major human ribonucleoprotein (RNP) autoantigens in Escherichia coli and their use in an EIA for screening sera from patients with autoimmune diseases.

1989 • 14 citations

Identification and characterization of the small nuclear ribonucleoprotein particle D' core protein.

1990 • 14 citations

Autoantibodies to Nonhistone Nuclear Antigens

1985 • 12 citations

Anti-SM and anti-U1-RNP lupus antibody fine specificities

1989 • 12 citations

Regulated Expression of the Small Nuclear Ribonucleoprotein Particle Protein SmN in Embryonic Stem Cell Differentiation

1990 • 9 citations

Identification of immunoreactive domains of the snRNP polypeptides Sm-B?/B and Sm-D

1990 • 4 citations

Identification and Characterization of the Small Nuclear Ribonucleoprotein Particle D' Core Protein

1990 • 3 citations

An Investigation into the Differential Stability of Sm Polypeptides Using Human and Murine Monoclonal Antibodies

1985 • 3 citations