Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases

Chronic graft-versus-host syndrome in man

1980 • 2,438 citations

HLA and Disease 1982 ‐ A Survey

1983 • 551 citations

Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids.

1981 • 544 citations

COOPERATING AND CONTROLLING FUNCTIONS OF THYMUS-DERIVED LYMPHOCYTES IN RELATION TO AUTOIMMUNITY

1971 • 534 citations

Regulation of B-Cell Growth and Differentiation by Soluble Factors

1983 • 432 citations

Origin and Function of Epidermal Langerhans Cells

1980 • 406 citations

HYDRALAZINE-INDUCED SYSTEMIC LUPUS ERYTHEMATOSUS: INFLUENCE OF HLA-DR AND SEX ON SUSCEPTIBILITY

1980 • 380 citations

Lymphokine stimulation of collagen accumulation.

1976 • 322 citations

Lymphocyte Differentiation, Recognition, and Regulation

1977 • 320 citations

HLA-DR Antigens and Toxic Reaction to Sodium Aurothiomalate and D-Penicillamine in Patients with Rheumatoid Arthritis

1980 • 295 citations

A systemic lupus erythematosus (SLE)‐like disease in mice induced by abnormal T‐B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1982 • 267 citations

Immunology: The science of self-nonself discrimination

1982 • 242 citations

Induction of Ia antigen in rat epidermal cells and gut epithelium by immunological stimuli.

1982 • 239 citations

The Cellular and Genetic Basis of Murine Lupus

1981 • 195 citations

Antigen Presentation by Vascular Endothelial Cells and Epidermal Langerhans Cells: The Role of HLA‐DR

1982 • 173 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 162 citations

Variable expression of Ia antigens on the vascular endothelium of mouse skin allografts

1983 • 143 citations

Allosuppressor- and allohelper-T cells in acute and chronic graft-vs.-host (GVH) disease. III. Different Lyt subsets of donor T cells induce different pathological syndromes.

1983 • 135 citations

Immunology: The science of self-nonself discrimination

1983 • 127 citations

Studies on the mechanism of drug sensitization: T-cell-dependent popliteal lymph node reaction to diphenylhydantoin

1981 • 125 citations

Macrophage-Lymphocyte Synergy in the Production of Osteoclast Activating Factor

1974 • 121 citations

Allosuppressor and allohelper T cells in acute and chronic graft-vs.-host disease. II. F1 recipients carrying mutations at H-2K and/or I-A.

1983 • 118 citations

Clones of helper T cells mediate antigen-specific, H–2-restricted DTH

1981 • 112 citations

GENETIC SUSCEPTIBILITY TO SCLERODERMA-LIKE SYNDROME INDUCED BY VINYL CHLORIDE

1983 • 106 citations

Pseudolymphoma with mycosis fungoides manifestations, hyperresponsiveness to diphenylhydantoin, and lymphocyte disregulation

1982 • 105 citations

THE ABROGATION OF SHEEP ERYTHROCYTE TOLERANCE IN RATS BY MEANS OF THE TRANSFER OF ALLOGENEIC LYMPHOCYTES

1970 • 104 citations

Restrictions in the response to autologous thyroglobulin in the human.

1980 • 94 citations

GENETIC CONTROL OF THE IMMUNE RESPONSE

1972 • 84 citations

Quantitation of precipitating antibodies to certain soluble nuclear antigens in sle

1977 • 83 citations

Diseases caused by reactions of T lymphocytes towards incompatible structures of the major histocompatibility complex. VI. Autoantibodies characteristic of systemic lupus erythematosus induced by abnormal T-B cell cooperation across I-E.

1982 • 81 citations

Diseases caused by reactions of T lymphocytes to incompatible structures of the major histocompatibility complex. VII. Immune-complex glomerulonephritis.

1983 • 80 citations

Diphenylhydantoin interstitial nephritis. Roles of cellular and humoral immunologic injury

1978 • 76 citations

Nephrotoxic Mechanisms of Drugs and Environmental Toxins

1982 • 74 citations

Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. I. Alloreactive suppressor cells rather than killer T cells appear to be the decisive effector cells in lethal graft-vs.-host disease.

1982 • 67 citations

THE ALLOGENEIC EFFECT IN INBRED MICE

1973 • 62 citations

Diphenylhydantoin-induced hypersensitivity reaction

1965 • 60 citations

Immunoregulation and anti-nuclear antibodies in mercury-induced glomerulopathy in the rat.

1981 • 58 citations

Attempts at standardization of lupus-like graft-vs-host disease: inadvertent repopulation by DBA/2 spleen cells of H-2-different nonirradiated F1 mice.

1983 • 55 citations

Hypothesis: A model for generalised autoimmunity

1973 • 54 citations

Allosuppressor- and allohelper-T cells in acute and chronic graft-vs-host disease. IV. Activation of donor allosuppressor cells is confined to acute GVHD.

1984 • 51 citations

Metabolism of immunoglobulin A, lymphocyte function, and histocompatibility antigens in patients on anticonvulsants.

1978 • 50 citations

B cell activity in systemic lupus erythematosus: depressed in vivo humoral immune response to a primary antigen (haemocyanin) and increased in vitro spontaneous immunoglobulin synthesis.

1983 • 48 citations

Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease.

1984 • 48 citations

Phenytoin hypersensitivity

1980 • 42 citations

T Cell‐dependent B‐Cell proliferation and activation induced by administration of the drug diphenylhydantoin to mice

1983 • 37 citations

Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus

1983 • 31 citations

Analysis of murine T lymphocyte markers during the early phases of GvH-associated suppression of cytotoxic T lymphocyte responses.

1983 • 30 citations

Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. V. F1 mice with secondary chronic GVHD contain F1-reactive allohelper but no allosuppressor T cells.

1984 • 26 citations

Studies on the specificity of autoantibodies produced in systemic graft-vs-host disease.

1975 • 24 citations

INDUCTION OF A PRIMARY ANTIHAPTEN RESPONSE IN VIVO BY A GRAFT-VS.-HOST REACTION

1973 • 23 citations

Studies on the Specificity of Autoantibodies Produced in Systemic Graft-vs-Host Disease

1975 • 23 citations

Aplastic anemia and lymphoma in sjögren's syndrome

1980 • 22 citations

Arthritis and angioimmunoblastic lymphadenopathy.

1983 • 21 citations

Diseases caused by reactions of T lymphocytes to in compatible structures of the major histocompatibility complex. I. Autoimmune hemolytic anemia

1976 • 21 citations

Lymphomagenesis and Autoimmunization Caused by Reactions of T-Lymphocytes to Incompatible Structures of the Major Histocompatibility Complex: A Concept of Pathogenesis

1978 • 20 citations

Intra‐H‐2 and T cell requirements for the induction of maximal positive and negative allogeneic effects in vitro

1983 • 15 citations

The immunological properties of haptens coupled to thymus‐independent carrier molecules. II. The influence of the graft‐versus‐host reaction on primary antibody responses to hapten‐coupled polysaccharides and proteins

1974 • 15 citations

In vitro and in vivo allogeneic effects: differential modulation of B cell subpopulations.

1982 • 14 citations

The allogeneic effect: increased affinity of serum antibody produced during a secondary response

1973 • 13 citations

Injection of mouse thyroglobulin and/or adult thymectomy do not break tolerance to thyroglobulin during the lupus like graft versus host disease in mice.

1984 • 12 citations

In vivo allogeneic effects: shift in the isotype profile of primary TI-2 responses in mice undergoing graft-vs-host reaction.

1982 • 11 citations

Inhibitory T cells in haemopoietic failure

1984 • 4 citations