Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

1989 • 1,837 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Septic Shock in Humans

1990 • 1,170 citations

Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.

1991 • 1,134 citations

The Cardiovascular Response of Normal Humans to the Administration of Endotoxin

1989 • 1,096 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.

1993 • 832 citations

<scp>l</scp>‐N^G‐nitro arginine (<scp>l</scp>‐NOARG), a novel, <scp>l</scp>‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro

1990 • 769 citations

Pulmonary Hypertension in Severe Acute Respiratory Failure

1977 • 729 citations

Protective and pathological roles of nitric oxide in endotoxin shock

1992 • 594 citations

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

1990 • 562 citations

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

1990 • 536 citations

Effects of a nitric oxide synthase inhibitor in humans with septic shock

1994 • 521 citations

Nitric oxide‐mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock

1993 • 402 citations

Role of nitric oxide in maintaining vascular integrity in endotoxin‐induced acute intestinal damage in the rat

1990 • 369 citations

Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis.

1992 • 324 citations

Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury

1992 • 274 citations

The Role of the l-arginine: Nitric Oxide Pathway in Circulatory Shock

1994 • 224 citations

Pulmonary injury and prostaglandin production during endotoxemia in conscious sheep

1981 • 164 citations

NG-Monomethyl-L-arginine (NMA) restores arterial blood pressure but reduces cardiac output in a canine model of endotoxic shock

1991 • 147 citations

Detrimental Hemodynamic Effects of Nitric Oxide Synthase Inhibition in Septic Shock

1994 • 115 citations

Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits.

1992 • 104 citations

Nitric oxide inhalation attenuates pulmonary hypertension and improves gas exchange in endotoxin shock

1993 • 86 citations

Improved bioassay for the detection of porcine tumor necrosis factor using a homologous cell line: PK(15)

1993 • 57 citations

Inhaled nitric oxide: its effects on pulmonary circulation and airway smooth muscle cells.

1993 • 54 citations

Sympathetic regulation of skeletal muscle blood flow in the pig: a non‐adrenergic component likely to be mediated by neuropeptide Y

1993 • 39 citations

Ibuprofen attenuates plasma tumor necrosis factor activity during sepsis-induced acute lung injury

1991 • 33 citations

Activation of the l-Arginine-Nitric Oxide Pathway Is Involved in Vascular Hyporeactivity Induced by Endotoxin

1991 • 32 citations

Circulatory responses to endothelin-1 and nitric oxide with special reference to endotoxin shock and nitric oxide inhalation.

1993 • 29 citations

Activation of the L-Arginine-Nitric Oxide Pathway Is Involved in Vascular Hyporeactivity Induced by Endotoxin

1991 • 29 citations

Prostaglandin and thromboxane levels during endotoxin-induced respiratory failure in pigs

1987 • 21 citations

Arterial baroreceptor reflexes in young and old racing greyhounds

1981 • 13 citations