Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

1990 • 3,304 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

1987 • 1,182 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Oxidation of nitrogen oxides by bound dioxygen in hemoproteins

1981 • 633 citations

Nitric oxide synthase is a cytochrome P-450 type hemoprotein

1992 • 617 citations

N omega-hydroxy-L-arginine is an intermediate in the biosynthesis of nitric oxide from L-arginine.

1991 • 572 citations

Reactions of the bioregulatory agent nitric oxide in oxygenated aqueous media: Determination of the kinetics for oxidation and nitrosation by intermediates generated in the nitric oxide/oxygen reaction

1993 • 474 citations

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

1989 • 464 citations

Purification of a Ca²⁺/calmodulin‐dependent nitric oxide synthase from porcine cerebellum

1990 • 433 citations

Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide.

1992 • 368 citations

Comprehensive chemical kinetics

1973 • 282 citations

Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine

1992 • 254 citations

Activation of purified soluble guanylate cyclase by protoporphyrin IX.

1982 • 206 citations

Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine

1992 • 181 citations

Stoichiometry of the reaction of oxyhemoglobin with nitrite

1979 • 141 citations

Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man.

1993 • 134 citations

Trace Atmospheric Constituents: Properties, Transformations and Fates

1983 • 133 citations

From growth factor dependence to growth factor responsiveness: The genesis of an alveolar macrophage cell line

1987 • 116 citations

Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin.

1990 • 111 citations

Nitrosation by stimulated macrophages. Inhibitors, enhancers and substrates

1989 • 78 citations

A mechanism for the conversion of oxyhemoglobin to methemoglobin by nitrite.

1976 • 75 citations

Interactions of blood metalloproteins with nitrogen oxides and oxidant air pollutants

1979 • 41 citations

Trace atmospheric constituents. Properties, transformation and fates

1983 • 31 citations