Role of nitric oxide in maintaining vascular integrity in endotoxin‐induced acute intestinal damage in the rat

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

1989 • 1,837 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

1987 • 1,450 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Superoxide radicals in feline intestinal ischemia

1981 • 1,213 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage.

1978 • 1,117 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Synthesis of nitric oxide from <scp>l</scp>-arginine by neutrophils. Release and interaction with superoxide anion

1989 • 529 citations

Phagocyte-generated oxygen metabolites and cellular injury.

1982 • 457 citations

Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat

1990 • 454 citations

Control of regional blood flow by endothelium-derived nitric oxide.

1990 • 447 citations

Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide.

1980 • 356 citations

Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation

1989 • 270 citations

The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation

1989 • 254 citations

Septic shock. Hemodynamics and pathogenesis.

1983 • 229 citations

Lipopolysaccharide-mediated bovine endothelial cell injury in vitro.

1983 • 215 citations

Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment.

1983 • 211 citations

Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat

1987 • 185 citations

Septic Shock

1983 • 155 citations

Direct effects of E coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants.

1986 • 149 citations

Prostacyclin Reversal of Lethal Endotoxemia in Dogs

1981 • 88 citations

Picomole doses of platelet-activating factor predispose the gastric mucosa to damage by topical irritants

1986 • 72 citations

Salutary Effects of Prostacyclin in Endotoxic Shock

1980 • 61 citations

Increased intestinal formation of Paf in endotoxin‐induced damage in the rat

1987 • 54 citations

Relationship between PAF-acether and thromboxane A2 biosynthesis in endotoxin-induced intestinal damage in the rat

1989 • 47 citations

Lipopolysaccharide increases release of a nitric oxide-like factor from endothelial cells

1989 • 28 citations

Beneficial effects of prostacyclin in a rabbit endotoxin shock model

1988 • 19 citations

Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.

1985 • 8 citations