Role of endothelium-derived nitric oxide in the regulation of blood pressure.

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

1987 • 5,027 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

1988 • 1,379 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

1989 • 862 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium

1987 • 765 citations

The nature of endothelium-derived vascular relaxant factor

1984 • 591 citations

Identification of arginine as a precursor of endothelium-derived relaxing factor.

1988 • 407 citations

Arginine is a physiological precursor of endothelium-derived nitric oxide

1988 • 392 citations

Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition.

1984 • 367 citations

Quantitative and kinetic characterization of nitric oxide and EDRF released from cultured endothelial cells

1988 • 342 citations

Decreased Endothelium-dependent Relaxation in New Zealand Genetic Hypertensive Rats

1984 • 189 citations

Endothelium-dependent responses in carotid and renal arteries of normotensive and hypertensive rats.

1988 • 157 citations

Vasodilatation by acetylcholine is endothelium‐dependent: a study by sonomicrometry in canine femoral artery in vivo.

1983 • 125 citations

Acetylcholine induces vasodilatation in the rabbit isolated heart through the release of nitric oxide, the endogenous nitrovasodilator

1988 • 117 citations

Laser-induced endothelial damage inhibits endothelium-dependent relaxation in the cerebral microcirculation of the mouse.

1987 • 102 citations

Vascular relaxation and cGMP in hypertension

1988 • 67 citations

Endothelium dependent vascular relaxation by arginine containing polypeptides

1986 • 46 citations

Preparation and characterization of Ng-mono-, di- and trimethylated arginines.

1977 • 34 citations

Chronic treatment with SCH 23390, a selective dopamine D-1 receptor antagonist, decreases dopamine metabolism in rat caudate nucleus

1988 • 25 citations

INHIBITION OF VASODILATATION BY METHYLENE BLUE IN LARGE AND SMALL ARTERIES OF THE DOG HINDLIMB IN VIVO

1988 • 18 citations

Gossypol attenuates selectively the blood pressure lowering effect of endothelium-dependent vasodilators in the rabbit in vivo

1988 • 15 citations