Prolonged Dexmedetomidine Infusion as an Adjunct in Treating Sedation-Induced Withdrawal

Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult

2002 • 1,858 citations

Sedative, Amnestic, and Analgesic Properties of Small-Dose Dexmedetomidine Infusions

2000 • 1,058 citations

Alpha‐2 and imidazoline receptor agonistsTheir pharmacology and therapeutic role

1999 • 684 citations

Respiratory effects of dexmedetomidine in the surgical patient requiring intensive care

2000 • 460 citations

Complications of sedation with midazolam in the intensive care unit and a comparison with other sedative regimens

1998 • 392 citations

Effects of Clonidine on Narcotic Requirements and Hemodynamic Response during Induction of Fentanyl Anesthesia and Endotracheal Intubation

1986 • 349 citations

The effect of lesions of ascending noradrenaline pathways on sleep and waking in the rat

1974 • 205 citations

Benzodiazepine Withdrawal: outcome in 50 patients

1987 • 154 citations

Potentiation of the Analgesic Properties of Fentanyl-like Opioids with α2-Adrenoceptor Agonists in Rats

1994 • 121 citations

Effects of Dexmedetomidine, a Novel Imidazole Sedative-Anesthetic Agent, on Adrenal Steroidogenesis

1991 • 97 citations

Clonidine and other alpha2 adrenergic agonists: Strategies for the rational use of these novel anesthetic agents

1988 • 56 citations

Dissociation of Tolerance and Dependence for Opioid Peripheral Antinociception in Rats

1997 • 48 citations

Pathophysiological and pharmacological mechanisms of acute cocaine toxicity in conscious rats.

1992 • 47 citations

Effect of ?2-adrenoceptor agonists on the expression of morphine-withdrawal in rats

1992 • 23 citations

α_2A‐Adrenergic receptors are present in μ‐opioid receptor containing neurons in rat medial nucleus tractus solitarius

2001 • 19 citations

Dexmedetomidine Partially Attenuates the Sympathetically Mediated Systemic and Coronary Hemodynamic Effects of Cocaine

1995 • 14 citations