The effect of lesions of ascending noradrenaline pathways on sleep and waking in the rat

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Brain stem reticular formation and activation of the EEG

1949 • 4,188 citations

The rat brain: A stereotaxic atlas of the forebrain and lower parts of the brain stem

1986 • 4,155 citations

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

FLUORESCENCE OF CATECHOL AMINES AND RELATED COMPOUNDS CONDENSED WITH FORMALDEHYDE

1962 • 2,684 citations

Evidence for the existence of monoamine neurons in the central nervous system

1965 • 1,538 citations

6-hydroxy-dopamine induced degeneration of central monoamine neurons

1968 • 1,419 citations

Biogenic Amines and the States of Sleep

1969 • 1,274 citations

Cellular localization of brain monoamines.

1962 • 1,141 citations

The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle

1972 • 1,091 citations

A Method for the Fluorimetric Determination of Adrenaline and Noradrenaline in Tissues.¹

1958 • 1,029 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. II. EXPERIMENTALLY INDUCED CHANGES IN THE INTRANEURONAL AMINE LEVELS OF BULBOSPINAL NEURON SYSTEMS.

1965 • 1,004 citations

[Research on the neural structures and responsible mechanisms in different phases of physiological sleep].

1962 • 908 citations

The Metabolism of Fatty Acids in the Rat VI. Arachidonic Acid

1965 • 866 citations

Demonstration and mapping out of nigro-neostriatal dopamine neurons

1964 • 796 citations

6-Hydroxydopamine and catecholamine neurons

1971 • 637 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

On the projections from the locus coeruleus noradrenaline neurons: The cerebellar innervation

1971 • 477 citations

The sleep-waking cycle

1972 • 476 citations

Effect upon the EEG of acute injury to the brain stem activating system

1949 • 431 citations

Biochemical and Histochemical Studies on the Effects of Imipramine‐like Drugs and (+)‐Amphetamine on Central and Peripheral Catecholamine Neurons

1966 • 414 citations

Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine

1973 • 350 citations

Projections of the nucleus locus coeruleus in the albino rat

1969 • 338 citations

Metabolism of amines in the brain.

1969 • 321 citations

Dynamic Response of Chest Wall and Lung Injuries in Rabbits Exposed to Air Shock Waves of Short Duration

1964 • 296 citations

Specificity of 6-hydroxydopamine induced degeneration of central monoamine neurones: An electron and fluorescence microscopic study with special reference to intracerebral injection on the nigro-striatal dopamine system

1973 • 295 citations

Minor tranquillizers, stress and central catecholamine neurons

1971 • 279 citations

Stimulation and destruction of the locus coeruleus: Opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex

1973 • 258 citations

The effect of lesions of catecholamine-containing neurons upon monoamine content of the brain and EEG and behavioral waking in the cat

1973 • 250 citations

Further mapping out of central noradrenaline neuron systems: Projections of the ‘subcoeruleus’ area

1972 • 245 citations

Regulation of monoamine metabolism in the central nervous system.

1972 • 241 citations

Projections ascendantes du locus coeruleus et d'autres neurones aminergiques pontiques au niveau du prosencéphale du rat

1972 • 232 citations

Inhibition of adrenergic neurotransmission by clonidine: An action on prejunctional α-receptors

1973 • 225 citations

Dopamine and noradrenaline receptor stimulation: Reversal of reserpine-induced suppression of motor activity

1973 • 210 citations

Studies on central and peripheral noradrenaline neurons using a new dopamine-β-hydroxylase inhibitor

1970 • 192 citations

Quantitation of Fluorescence of Biogenic Monoamines

1971 • 187 citations

Drug‐induced changes in the release of [³H]‐noradrenaline from field stimulated rat iris

1971 • 186 citations

Ultramorphologische Ver�nderungen der sympathischen Nervenendigungen der Katze nach Vorbehandlung mit 5- und 6-Hydroxy-Dopamin

1967 • 166 citations

Injection of 6-hydroxydopamine into the substantia nigra of the rat. II. Diffusion and specificity

1973 • 159 citations

Norepinephrine-Containing Neurons: Changes in Spontaneous Discharge Patterns during Sleeping and Waking

1973 • 157 citations

A simple high capacity freeze-drier for histochemical use

1970 • 149 citations

Non-specific histopathological changes induced by the intracerebral injection of 6-hydroxy-dopamine (6-OH-DA)

1972 • 149 citations

The effect of chlordiazepoxide, diazepam and nitrazepam on catecholamine metabolism in regions of the rat brain

1969 • 145 citations

Sedative effects of α-sympathomimetic drugs and their antagonism by adrenergic and cholinergic blocking drugs

1971 • 134 citations

Injection of 6-hydroxydopamine in the substantia nigra of the rat. I. Morphological study

1973 • 131 citations

Barbiturates and meprobamate: Decreases in catecholamine turnover of central dopamine and noradrenaline neuronal systems and the influence of immobilization stress

1972 • 130 citations

Further studies on the accumulation and disappearance of catecholamines formed from tyrosine-14C in mouse brain. Effect of some phenothiazine analogues

1970 • 115 citations

Reticular influences on the EEG

1964 • 108 citations

The nucleus locus coeruleus (dorsolateralis tegmenti).

1955 • 106 citations

Excitability changes during the sleep cycle of the rat

1963 • 104 citations

Kinetics of H3-norepinephrine accumulation into slices from different regions of the rat brain.

1968 • 94 citations

DEGENERATION OF CENTRAL AND PERIPHERAL NORADRENALINE NEURONS PRODUCED BY 6‐HYDROXY‐DOPA

1972 • 93 citations

THE HISTOCHEMICAL FLUORESCENCE METHOD FOR THE DEMONSTRATION OF CATECHOLAMINES THEORY, PRACTICE AND APPLICATION

1973 • 90 citations

Immunohistochemical localization of dopamine- -hydroxylase in the peripheral and central nervous system.

1970 • 86 citations

Insomnia and Decrease of Cerebral 5-Hydroxytryptamine after Destruction of the Raphe System in the Cat

1968 • 86 citations

Mapping of central noradrenaline pathways with 6-Hydroxy-DOPA

1973 • 83 citations

On the function of central catecholamine neurons--their role in cardiovascular and arousal mechanisms.

1972 • 82 citations

SEMIQUANTITATIVE ESTIMATION OF FORMALDEHYDE-INDUCED FLUORESCENCE OF NORADRENALINE IN CENTRAL NORADRENALINE NERVE TERMINALS

1971 • 78 citations

Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways

1973 • 78 citations

Spontaneous discharge of Purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine

1971 • 78 citations

Monoamine fluorescence in CNS smears: sensitive and rapid visualization of nerve terminals without freeze-drying

1970 • 77 citations

Sleep produced by clonidine (2‐(2,6‐dichlorophenylamino)‐2‐imidazoline hydrochloride)

1971 • 75 citations

NORADRENALINE NERVE TERMINALS IN THE CEREBRAL CORTEX: EFFECTS ON NORADRENALINE UPTAKE AND STORAGE FOLLOWING AXONAL LESION WITH 6-HYDROXYDOPAMINE

1974 • 70 citations

Effects of 6-Hydroxydopamine on Sleep in the Rat

1971 • 70 citations

Olfactory arousal reactions in the “cerveau isolé” cat

1953 • 59 citations

The respective involvement of noradrenaline and its deaminated metabolites in waking and paradoxical sleep: A neuropharmacological model

1972 • 55 citations

Alpha-methylparatyrosine and sleep in the rat

1971 • 49 citations

Synthesis of catecholamines in the locus coeruleus from 3H-tyrosine in vivo

1972 • 41 citations

The effects of 6-Hydroxydopamine, Dopamine and dl-Norepinephrine on food intake and water consumption, self-stimulation, temperature and electroencephalographic activity in the rat

1973 • 39 citations

Catechol‐O‐Methyl Transferase Inhibitors. In Vivo Inhibition in Mice

1964 • 36 citations

Effect of Alpha-Methyltyrosine on Sleep in the Rat

1967 • 34 citations

Uptake and release of noradrenaline in rat cerebral cortex in vitro: No effect of benzodiazepines and barbiturates

1973 • 34 citations

Effect of changes of brain norepinephrine content on sleep cycle in rat

1968 • 34 citations

Effects of intracerebral injections of 6-hydroxydopamine on sleep and waking in the rat

1973 • 33 citations

6-Hydroxydopamine intracisternale et sommeil chez le rat

1973 • 30 citations

The effect of unilateral and bilateral lesions in the locus coeruleus on the levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) in neocortex

1973 • 18 citations

Effect of α-methyltyrosine on the electrocorticogram of unrestrained rats

1968 • 17 citations

Effects of L-DOPA on the EEG and brain amines of unrestrained rats

1972 • 17 citations