α-Bungarotoxin Receptors Contain α7 Subunits in Two Different Disulfide-Bonded Conformations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1990 • 1,756 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

1992 • 1,230 citations

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1997 • 1,142 citations

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

1993 • 1,040 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

Prion Protein Biology

1998 • 913 citations

The structure of an antigenic determinant in a protein

1984 • 841 citations

Nicotinic Receptors in the Development and Modulation of CNS Synapses

1996 • 771 citations

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins

1995 • 614 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1990 • 471 citations

Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum.

1992 • 405 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues.

1986 • 361 citations

Folding of influenza hemagglutinin in the endoplasmic reticulum.

1991 • 318 citations

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

1989 • 279 citations

Neurotransmitter action: Opening of ligand-gated ion channels

1993 • 267 citations

alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability

1995 • 264 citations

Nicotinic receptors that bind α-bungarotoxin on neurons raise intracellular free ca2+

1992 • 263 citations

d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor.

1990 • 256 citations

Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels

1994 • 254 citations

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

1994 • 246 citations

Comparison of the regional expression of nicotinic acetylcholine receptor ?7 mRNA and [125I]-?-bungarotoxin binding in human postmortem brain

1997 • 233 citations

Schizophrenia and Nicotinic Receptors

1994 • 224 citations

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

1994 • 210 citations

Assembly in vivo of mouse muscle acetylcholine receptor: Identification of an α subunit species that may be an assembly intermediate

1983 • 204 citations

The α-Bungarotoxin-binding Nicotinic Acetylcholine Receptor from Rat Brain Contains Only the α7 Subunit

1997 • 200 citations

Ion-channel assembly.

1995 • 181 citations

Functional Contribution of Neuronal AChR Subunits Revealed by Antisense Oligonucleotides

1991 • 164 citations

Identification of a New Component of the Agonist Binding Site of the Nicotinic α7 Homooligomeric Receptor

1995 • 147 citations

Structural Dynamics of the Streptomyces lividans K⁺ Channel (SKC1): Oligomeric Stoichiometry and Stability^,

1997 • 145 citations

Ion-channel assembly

1995 • 143 citations

The fall and rise of neuronal α-bungarotoxin binding proteins

1992 • 135 citations

Host Cell‐Specific Folding and Assembly of the Neuronal Nicotinic Acetylcholine Receptor α7 Subunit

1997 • 134 citations

Diversity of nicotinic acetylcholine receptors in rat brain. V. alpha-Bungarotoxin-sensitive nicotinic receptors in olfactory bulb neurons and presynaptic modulation of glutamate release.

1996 • 133 citations

A role for the nicotinic α-bungarotoxin receptor in neurite outgrowth in PC12 cells

1993 • 133 citations

Cyclic AMP regulates the proportion of functional acetylcholine receptors on chicken ciliary ganglion neurons.

1987 • 131 citations

Regulation of α₇Nicotinic Acetylcholine Receptors in the Developing Rat Somatosensory Cortex by Thalamocortical Afferents

1996 • 123 citations

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

1987 • 119 citations

Promoter-cDNA-directed heterologous protein expression in Xenopus laevis oocytes.

1992 • 116 citations

Prolyl isomerase requirement for the expression of functional homo-oligomeric ligand-gated ion channels

1994 • 108 citations

Functional expression of nicotinic acetylcholine receptors containing rat α7 subunits in human SH‐SY5Y neuroblastoma cells

1994 • 103 citations

Genetic Reconstitution of Functional Acetylcholine Receptor Channels in Mouse Fibroblasts

1987 • 100 citations

Similarity Between Rat Brain Nicotinic α‐Bungarotoxin Receptors and Stably Expressed α‐Bungarotoxin Binding Sites

1996 • 92 citations

Neuronal α-Bungarotoxin Receptors Differ Structurally from Other Nicotinic Acetylcholine Receptors

1997 • 90 citations

The Role of the Cystine Loop in Acetylcholine Receptor Assembly

1997 • 87 citations

Nicotinic acetylcholine currents in cultured postnatal rat hippocampal neurons.

1992 • 84 citations

Detection of Functional Nicotinic Receptors Blocked by α-Bungarotoxin on PC12 Cells and Dependence of Their Expression on Post-Translational Events

1997 • 83 citations

Efficiency of acetylcholine receptor subunit assembly and its regulation by cAMP.

1991 • 74 citations

Fibroblasts transfected with Torpedo acetylcholine receptor beta-, gamma-, and delta-subunit cDNAs express functional receptors when infected with a retroviral alpha recombinant.

1989 • 72 citations

Assembly of mutant subunits of the nicotinic acetylcholine receptor lacking the conserved disulfide loop structure.

1992 • 65 citations

Contributions of N‐Linked Glycosylation to the Expression of a Functional α7‐Nicotinic Receptor in Xenopus Oocytes

1998 • 65 citations

Peptidyl prolyl cis-trans isomerase activity of cyclophilin A in functional homo-oligomeric receptor expression

1997 • 62 citations

Acetylcholine receptor in a C2 muscle cell variant is retained in the endoplasmic reticulum.

1989 • 55 citations

Water-soluble Nicotinic Acetylcholine Receptor Formed by α7 Subunit Extracellular Domains

1998 • 42 citations

Expression and Circular Dichroism Studies of the Extracellular Domain of the α Subunit of the Nicotinic Acetylcholine Receptor

1997 • 37 citations

Cyclic AMP-dependent mechanism regulates acetylcholine receptor function on bovine adrenal chromaffin cells and discriminates between new and old receptors.

1988 • 36 citations

[26] Stable expression of heterologous multisubunit protein complexes established by calcium phosphate- or lipid-mediated cotransfection

1992 • 21 citations

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