Intercellular transfer of antigen‐presenting cell determinants onto T cells: molecular mechanisms and biological significance

Functional rafts in cell membranes

1997 • 9,471 citations

Cell Signaling by Receptor Tyrosine Kinases

2010 • 7,477 citations

Models for the Specific Adhesion of Cells to Cells

1978 • 4,159 citations

Cell Signaling by Receptor Tyrosine Kinases

2000 • 3,570 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1999 • 1,484 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I

2001 • 1,239 citations

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

1995 • 1,143 citations

Molecular Characterization of Dendritic Cell-Derived Exosomes

1999 • 1,005 citations

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

2001 • 852 citations

The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges

2001 • 796 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

A Novel Adaptor Protein Orchestrates Receptor Patterning and Cytoskeletal Polarity in T-Cell Contacts

1998 • 708 citations

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

1996 • 684 citations

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1990 • 675 citations

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling

2000 • 657 citations

Phosphatidylinositol 4,5-Bisphosphate Functions as a Second Messenger that Regulates Cytoskeleton–Plasma Membrane Adhesion

2000 • 651 citations

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

1998 • 630 citations

A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation

1998 • 625 citations

B cells acquire antigen from target cells after synapse formation

2001 • 606 citations

Receptor-Mediated Antigen Uptake and its Effect on Antigen Presentation to Class II-Restricted T Lymphocytes

1990 • 605 citations

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton.

1995 • 528 citations

Physical Chemistry of Biological Interfaces

1999 • 486 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

Cell control by membrane–cytoskeleton adhesion

2001 • 458 citations

TCR-Mediated Internalization of Peptide-MHC Complexes Acquired by T Cells

1999 • 456 citations

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

1996 • 452 citations

Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

2000 • 448 citations

THE DYNAMICS OF T CELL RECEPTOR SIGNALING: Complex Orchestration and the Key Roles of Tempo and Cooperation

1999 • 439 citations

Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation

1997 • 399 citations

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion

1988 • 372 citations

Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide.

1994 • 367 citations

On the Dynamics of TCR:CD3 Complex Cell Surface Expression and Downmodulation

2000 • 364 citations

Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

2000 • 327 citations

Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation

1997 • 316 citations

Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

1991 • 298 citations

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

1992 • 285 citations

Shedding of ICAM-1 from human melanoma cell lines induced by IFN-gamma and tumor necrosis factor-alpha. Functional consequences on cell-mediated cytotoxicity.

1991 • 281 citations

Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

1996 • 274 citations

Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells

1999 • 259 citations

In Vivo Transfer of GPI-Linked Complement Restriction Factors from Erythrocytes to the Endothelium

1995 • 254 citations

Recovery of human neutrophils from complement attack: removal of the membrane attack complex by endocytosis and exocytosis.

1987 • 251 citations

T Cells Can Use Either T Cell Receptor or Cd28 Receptors to Absorb and Internalize Cell Surface Molecules Derived from Antigen-Presenting Cells

2000 • 249 citations

Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition

1997 • 235 citations

Cutting Edge: CTLs Rapidly Capture Membrane Fragments from Target Cells in a TCR Signaling-Dependent Manner

2001 • 220 citations

Shedding from the Cell Surface of Normal and Cancer Cells

1980 • 215 citations

B cells extract and present immobilized antigen: implications for affinity discrimination

2000 • 199 citations

Intercellular Transfer and Supramolecular Organization of Human Leukocyte Antigen C at Inhibitory Natural Killer Cell Immune Synapses

2001 • 189 citations

Mechanism and kinetics of transfer of a fluorescent fatty acid between single-walled phosphatidylcholine vesicles

1980 • 185 citations

Spatial Organization of Signal Transduction Molecules in the NK Cell Immune Synapses During MHC Class I-Regulated Noncytolytic and Cytolytic Interactions

2001 • 183 citations

The bride of sevenless and sevenless interaction: Internalization of a transmembrane ligand

1992 • 172 citations

Class II MHC/Peptide Complexes Are Released from APC and Are Acquired by T Cell Responders During Specific Antigen Recognition

1999 • 154 citations

Comparative lipid analysis of purified plasma membranes and shed extracellular membrane vesicles from normal murine thymocytes and leukemic GRSL cells

1982 • 153 citations

Internalized Epidermal Growth Factor Receptors Participate in the Activation of p21 in Fibroblasts

1999 • 151 citations

Cell surface appearance of unexpected host MHC determinants on thymocytes from radiation bone marrow chimeras.

1981 • 135 citations

Endocytosis and mitogenic signaling

1999 • 131 citations

I-A antigens on cloned alloreactive murine T lymphocytes are acquired passively.

1982 • 128 citations

Effect of Epidermal Growth Factor Receptor Internalization on Regulation of the Phospholipase C-γ1 Signaling Pathway

1999 • 127 citations

Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism

2000 • 122 citations

Soluble CD86 Is a Costimulatory Molecule for Human T Lymphocytes

2000 • 120 citations

Biochemical complexity of serum HLA class I molecules

1988 • 117 citations

Essential requirement for major histocompatibility complex recognition in T-cell tolerance induction

1984 • 117 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2014 • 112 citations

Physiological enzymatic cleavage of leukocyte membrane molecules

1995 • 110 citations

TCR-Induced Transmembrane Signaling by Peptide/MHC Class II Via Associated Ig-α/β Dimers

2001 • 108 citations

Soluble ICAM-1 Activates Lung Macrophages and Enhances Lung Injury

1998 • 107 citations

Shedding of c-Met is regulated by crosstalk between a G-protein coupled receptor and the EGF receptor and is mediated by a TIMP-3 sensitive metalloproteinase

2001 • 105 citations

Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether

2001 • 102 citations

Acquisition of External Major Histocompatibility Complex Class I Molecules by Natural Killer Cells Expressing Inhibitory Ly49 Receptors

2001 • 102 citations

The Efficiency of Antigen Recognition by CD8+ CTL Clones Is Determined by the Frequency of Serial TCR Engagement

1998 • 96 citations

Vesicles bearing MHC class II molecules mediate transfer of antigen from antigen-presenting cells to CD4+ T cells

1999 • 95 citations

Fatty acid transfer between multilamellar liposomes and fatty acid-binding proteins.

1984 • 88 citations

Specific binding of K- and I-region products of the H-2 complex to activated thymus-derived (T) cells belonging to different Ly subclasses.

1976 • 82 citations

H-2D Ligand Expression by Ly49A+ Natural Killer (NK) Cells Precludes Ligand Uptake from Environmental Cells

2001 • 77 citations

Signal extinction and T cell repolarization in T helper cell‐antigen‐presenting cell conjugates

1996 • 76 citations

Antigen presentation by T cells: T cell receptor ligation promotes antigen acquisition from professional antigen‐presenting cells

1997 • 74 citations

Shedding of adhesion receptors from the surface of activated platelets

1994 • 66 citations

Detachment of agglutinin-bonded red blood cells. II. Mechanical energies to separate large contact areas

1991 • 66 citations

Antibody-Induced Shedding of CD44 from Adherent Cells Is Linked to the Assembly of the Cytoskeleton

2001 • 64 citations

Role of the Actin Cytoskeleton in T Cell Absorption and Internalization of Ligands from APC

2001 • 58 citations

Activated T Cells Acquire Endothelial Cell Surface Determinants During Transendothelial Migration

1999 • 58 citations

The Cytoplasmic Domain of L-Selectin Participates in Regulating L-Selectin Endoproteolysis

2001 • 56 citations

The soluble IL-6 receptors: serum levels and biological function.

2001 • 56 citations

Degradation of ZAP-70 Following Antigenic Stimulation in Human T Lymphocytes: Role of Calpain Proteolytic Pathway

1999 • 56 citations

Studies on the induction and expression of T cell-mediated immunity

1979 • 54 citations

Use of conjugates made between a cytolytic T cell clone and target cells to study the redistribution of membrane molecules in cell contact areas

1990 • 51 citations

Transfer of antigen from macrophages to lymphocytes. II. Immunological significance of the transfer of lipopolysaccharide.

1973 • 45 citations

Soluble selectins and ICAM-1 modulate neutrophil-endothelial adhesion and diapedesis in vitro.

1997 • 43 citations

A dominant-negative mutant of the Rab5 GTPase enhances T cell signaling by interfering with TCR down-modulation in transgenic mice.

1997 • 40 citations

Calcium responses elicited in human T cells and dendritic cells by cell–cell interaction and soluble ligands

1999 • 37 citations

Signaling by E-selectin and ICAM-1 Induces Endothelial Tissue Factor Production via Autocrine Secretion of Platelet-Activating Factor and Tumor Necrosis Factor α

1995 • 34 citations

Macrophage—T cell interactions

1978 • 34 citations

Quantitative aspects of T-cell recognition: from within the antigen-presenting cell to within the T cell

1998 • 33 citations

The immunological relay race: B cells take antigen by synapse

2001 • 30 citations

Reproducible dissociation of cellular aggregates with a wide range of calibrated shear forces: Application to cytolytic lymphocyte-target cell conjugates

1983 • 26 citations

Dynamic study of cell mechanical and structural responses to rapid changes of calcium level

2000 • 22 citations

Patrilocal∗∗patrilocal: taking the bride to the husband's home village cell-cell interactions: sevenless captures its bride

1993 • 16 citations

Unexpected cell surface labeling in conjugates between cytotoxic T lymphocytes and target cells.

1985 • 12 citations

Quantification of the nonspecific intercellular transfer of fluorescent molecules between labeled and unlabeled rat thymocytes

1987 • 6 citations

Analysis of cell structural and functional diversity by combination of micromanipulation and microfluorimetry

1987 • 4 citations

Calcium responses elicited in human T cells and dendritic cells by cell–cell interaction and soluble ligands

1999 • 3 citations

Deleted Work

1955 • 0 citations