Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

The Fas Death Factor

1995 • 4,070 citations

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

Metalloproteinase-mediated release of human Fas ligand.

1995 • 835 citations

Induction of Immunological Tolerance by Porcine Liver Allografts

1969 • 826 citations

Use of a Monoclonal Antibody (W6/32) in Structural Studies of HLA-A,B,C Antigens

1979 • 682 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Chapter 9 The End of the (Cell) Line: Methods for the Study of Apoptosis in Vitro

1995 • 569 citations

Liver Transplantation

1989 • 300 citations

Presence of hematopoietic stem cells in the adult liver

1996 • 300 citations

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

1993 • 251 citations

Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2

1978 • 239 citations

Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway.

1986 • 220 citations

Anti HL-A2 Inhibitor in Normal Human Serum

1970 • 216 citations

Purified perforin induces target cell lysis but not DNA fragmentation.

1989 • 162 citations

Soluble HL-A7 Antigen: Localization in the β-Lipoprotein Fraction of Human Serum

1970 • 156 citations

Secretion of a transplantation-related antigen

1983 • 150 citations

Inhibition of alloreactive cytotoxic T lymphocytes by peptides from the α2 domain of HLA–A2

1987 • 146 citations

Patterns of donor-type microchimerism after heart transplantation

1994 • 140 citations

The essential roles of parenchymal tissues and passenger leukocytes in the tolerance induced by liver grafting in rats

1995 • 138 citations

HLA-A2 peptides can regulate cytolysis by human allogeneic T lymphocytes

1987 • 132 citations

Serum HLA class I antigens: markers and modulators of an immune response?

1995 • 121 citations

Biochemical complexity of serum HLA class I molecules

1988 • 117 citations

SIMULTANEOUS LIVER AND RENAL TRANSPLANTATION IN MAN

1988 • 117 citations

Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis.

1989 • 105 citations

Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness.

1995 • 101 citations

Expression of two distinct cytolytic mechanisms among murine CD4 subsets.

1990 • 84 citations

Organ graft tolerance: the liver effect

1994 • 81 citations

Soluble MHC class I antigens (sHLA) and anti‐HLA antibodies in heart and kidney allograft recipients

1993 • 79 citations

Evidence for multiple lytic pathways used by cytotoxic T lymphocytes.

1989 • 74 citations

Interaction of papain-digested HLA class I molecules with human alloreactive cytotoxic T lymphocytes (CTL)

1993 • 69 citations

I-Kk and H-2Kk antigens are shed as supramolecular particles in association with membrane lipids.

1981 • 69 citations

Molecular interactions required for triggering alloantigen-specific cytolytic T lymphocytes.

1989 • 68 citations

INHIBITION OF ANTI-HLA-B7 ALLOREACTIVE CTL BY AFFINITY-PURIFIED SOLUBLE HLA

1991 • 64 citations

Biochemical characterization of 39-kDa class I histocompatibility antigen in plasma. A secretable membrane protein derived from transmembrane domain deletion

1991 • 63 citations

Selective turnover and shedding of H-2K and H-2D antigens is controlled by the major histocompatibility complex. Implications for H-2-restricted recognition.

1980 • 57 citations

CHARACTERIZATION OF SOLUBLE HLA MOLECULES IN SWEAT AND QUANTITATIVE HLA DIFFERENCES IN SERUM OF HEALTHY INDIVIDUALS

1990 • 42 citations

Cytolytic T-lymphocyte response to isolated class I H–2 proteins and influenza peptides

1989 • 41 citations

Antigenic determinants of the HLA-B7 molecule; Bw6- and B7-specific determinants are spatially separate

1983 • 28 citations

Characterization of a B lymphoblastoid cell line mutant that secretes HLA-A2.

1984 • 25 citations

Quantitative and biochemical characterization of soluble HLA class I antigens shed by cultured human cells

1994 • 7 citations

Human islet cotransplantation with liver or kidney.

1992 • 6 citations