Revealing Posttranscriptional Regulatory Elements Through Network-Level Conservation

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

2005 • 4,706 citations

Combinatorial microRNA target predictions

2005 • 4,543 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Human MicroRNA Targets

2004 • 3,702 citations

MicroRNA targets in Drosophila

2003 • 3,228 citations

Systematic determination of genetic network architecture

1999 • 2,535 citations

Principles of MicroRNA–Target Recognition

2005 • 2,335 citations

Vienna RNA secondary structure server

2003 • 2,265 citations

Prediction of Plant MicroRNA Targets

2002 • 2,239 citations

The microRNA Registry

2003 • 2,203 citations

A microRNA in a Multiple-Turnover RNAi Enzyme Complex

2002 • 2,052 citations

Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

2005 • 1,895 citations

MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 • 1,680 citations

Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

2002 • 1,426 citations

The microRNAs ofCaenorhabditis elegans

2003 • 1,232 citations

The Evolution of Transcriptional Regulation in Eukaryotes

2003 • 1,207 citations

The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics

2003 • 964 citations

The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development

2004 • 944 citations

Involvement of MicroRNA in AU-Rich Element-Mediated mRNA Instability

2005 • 848 citations

Identification of Drosophila MicroRNA Targets

2003 • 792 citations

Extensive Association of Functionally and Cytotopically Related mRNAs with Puf Family RNA-Binding Proteins in Yeast

2004 • 661 citations

MicroRNAs, SNPs and Cancer

2011 • 616 citations

A PUF family portrait: 3′UTR regulation as a way of life

2002 • 601 citations

Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos

1999 • 527 citations

The Nonamer UUAUUUAUU Is the Key AU-Rich Sequence Motif That Mediates mRNA Degradation

1995 • 524 citations

A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line

1997 • 504 citations

Comparative genome sequencing ofDrosophila pseudoobscura: Chromosomal, gene, andcis-element evolution

2005 • 502 citations

The staufen/pumilio Pathway Is Involved in Drosophila Long-Term Memory

2003 • 464 citations

An Overview of Ensembl

2004 • 452 citations

microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets

2005 • 445 citations

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR

2004 • 441 citations

Binding of pumilio to maternal hunchback mRNA is required for posterior patterning in drosophila embryos

1995 • 419 citations

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

2003 • 354 citations

Computational identification of microRNA targets

2004 • 308 citations

NANOS-3 and FBF proteins physically interact to control the sperm–oocyte switch in Caenorhabditis elegans

1999 • 268 citations

Composition and dynamics of theCaenorhabditis elegansearly embryonic transcriptome

2003 • 262 citations

nanos and pumilio Are Essential for Dendrite Morphogenesis in Drosophila Peripheral Neurons

2004 • 197 citations

Principles of MicroRNATarget Recognition

2005 • 167 citations

MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model.

2004 • 153 citations

The K box, a conserved 3′ UTR sequence motif, negatively regulates accumulation of Enhancer of split Complex transcripts

1998 • 151 citations

Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach.

2005 • 129 citations

The Bearded box, a novel 3′ UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression

1997 • 118 citations

Using a Quantitative Blueprint to Reprogram the Dynamics of the Flagella Gene Network

2004 • 117 citations

Whole-Genome Discovery of Transcription Factor Binding Sites by Network-Level Conservation

2003 • 106 citations

PUM2, a novel murine puf protein, and its consensus RNA-binding site.

2001 • 106 citations

Novel functional role of CA repeats and hnRNP L in RNA stability

2003 • 79 citations

The Drosophila melanogaster Translational Repressor Pumilio Regulates Neuronal Excitability

2002 • 73 citations

The Drosophila gene Bearded encodes a novel small protein and shares 3′ UTR sequence motifs with multiple Enhancer of split Complex genes

1997 • 68 citations

Antagonism of Notch signaling activity by members of a novel protein family encoded by the Bearded and Enhancer of split gene complexes

2000 • 68 citations

CA Repeats in the 3′-Untranslated Region of bcl-2 mRNA Mediate Constitutive Decay of bcl-2 mRNA

2004 • 30 citations