Comparative genome sequencing ofDrosophila pseudoobscura: Chromosomal, gene, andcis-element evolution

Basic local alignment search tool

1990 • 87,358 citations

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

ANALYZING TABLES OF STATISTICAL TESTS

1989 • 14,038 citations

Basic Local Alignment Search Tool

1990 • 12,947 citations

Base-Calling of Automated Sequencer Traces UsingPhred. I. Accuracy Assessment

1998 • 6,925 citations

MEGA2: molecular evolutionary genetics analysis software

2001 • 6,215 citations

Analyzing Tables of Statistical Tests

1989 • 5,635 citations

Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities

1998 • 5,382 citations

Prediction of complete gene structures in human genomic DNA

1997 • 4,041 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

CLUSTAL V: improved software for multiple sequence alignment

1992 • 2,421 citations

Sequencing and comparison of yeast species to identify genes and regulatory elements

2003 • 1,785 citations

Human–Mouse Alignments with BLASTZ

2002 • 1,254 citations

LAGAN and Multi-LAGAN: Efficient Tools for Large-Scale Multiple Alignment of Genomic DNA

2003 • 1,103 citations

The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics

2003 • 964 citations

Chromosomal inversions and the reproductive isolation of species

2001 • 885 citations

Lengths of chromosomal segments conserved since divergence of man and mouse.

1984 • 599 citations

Temporal Patterns of Fruit Fly (Drosophila) Evolution Revealed by Mutation Clocks

2003 • 587 citations

Evidence for stabilizing selection in a eukaryotic enhancer element

2000 • 579 citations

Molecular phylogeny and divergence times of drosophilid species.

1995 • 567 citations

Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster

2002 • 542 citations

Phylogenetic Shadowing of Primate Sequences to Find Functional Regions of the Human Genome

2003 • 526 citations

AVID: A Global Alignment Program

2002 • 496 citations

Evidence for large domains of similarly expressed genes in the Drosophila genome

2002 • 483 citations

Integrating genomic homology into gene structure prediction

2001 • 471 citations

Retroposed New Genes Out of the X in Drosophila

2002 • 451 citations

Models of amino acid substitution and applications to mitochondrial protein evolution

1998 • 427 citations

Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans

2002 • 414 citations

Finishing a whole-genome shotgun: Release 3 of the Drosophila melanogastereuchromatic genome sequence

2002 • 399 citations

High intrinsic rate of DNA loss in Drosophila

1996 • 385 citations

Annotation of the Drosophila melanogastereuchromatic genome: a systematic review

2002 • 377 citations

ACCUMULATING POSTZYGOTIC ISOLATION GENES IN PARAPATRY: A NEW TWIST ON CHROMOSOMAL SPECIATION

2003 • 372 citations

Using <tt>GeneWise</tt> in the Drosophila Annotation Experiment

2000 • 368 citations

THE RELATIONS OF INVERSIONS IN THE X CHROMOSOME OF DROSOPHILA MELANOGASTER TO CROSSING OVER AND DISJUNCTION

1936 • 352 citations

Human and mouse genomic sequences reveal extensive breakpoint reuse in mammalian evolution

2003 • 350 citations

Rates of Conservative and Radical Nonsynonymous Nucleotide Substitutions in Mammalian Nuclear Genes

2000 • 349 citations

Ancient Linkage Groups and Frozen Accidents

1973 • 338 citations

GENETICS OF NATURAL POPULATIONS. XII. EXPERIMENTAL REPRODUCTION OF SOME OF THE CHANGES CAUSED BY NATURAL SELECTION IN CERTAIN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA

1946 • 328 citations

The K_A/K_S Ratio Test for Assessing the Protein-Coding Potential of Genomic Regions: An Empirical and Simulation Study

2001 • 278 citations

Functional analysis of eve stripe 2 enhancer evolution in Drosophila: rules governing conservation and change

1998 • 277 citations

Caloramator viterbensis sp. nov., a novel thermophilic, glycerol-fermenting bacterium isolated from a hot spring in Italy

2002 • 266 citations

THE HOMOLOGIES OF THE CHROMOSOME ELEMENTS IN THE GENUS DROSOPHILA

1941 • 251 citations

Contributions to the Genetics, Taxonomy, and Ecology of Drosophila Pseudoobscura and Its Relatives

1946 • 245 citations

SELECTION FOR RECOMBINATION IN SMALL POPULATIONS

2001 • 244 citations

Strategies and Tools for Whole-Genome Alignments

2003 • 228 citations

High rate of DNA loss in the Drosophila melanogaster and Drosophila virilis species groups

1998 • 226 citations

Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura.

2004 • 217 citations

Inversions in the Third Chromosome of Wild Races of Drosophila Pseudoobscura, and Their Use in the Study of the History of the Species

1936 • 209 citations

Generation of a Widespread Drosophila Inversion by a Transposable Element

1999 • 204 citations

Relationships within the melanogaster species subgroup of the genus Drosophila ( Sophophora ) - II. Phylogenetic relationships between six species based upon polytene chromosome banding sequences

1976 • 197 citations

Coexpression of Neighboring Genes in Caenorhabditis Elegans Is Mostly Due to Operons and Duplicate Genes

2003 • 194 citations

Mobilization of hobo elements residing within the decapentaplegic gene complex: Suggestion of a new hybrid dysgenesis system in Drosophila melanogaster

1987 • 190 citations

How Malleable is the Eukaryotic Genome? Extreme Rate of Chromosomal Rearrangement in the GenusDrosophila

2001 • 178 citations

The Atlas Genome Assembly System

2004 • 175 citations

Y Chromosome of D. pseudoobscura Is Not Homologous to the Ancestral Drosophila Y

2004 • 171 citations

GENETICS OF NATURAL POPULATIONS. XVI. ALTITUDINAL AND SEASONAL CHANGES PRODUCED BY NATURAL SELECTION IN CERTAIN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA PERSIMILIS

1948 • 168 citations

GENETICS OF NATURAL POPULATIONS. XVIII. EXPERIMENTS ON CHROMOSOMES OF DROSOPHILA PSEUDOOBSCURA FROM DIFFERENT GEOGRAPHIC REGIONS

1948 • 156 citations

FORMATION OF CHROMOSOME REARRANGEMENTS BY P FACTORS IN DROSOPHILA

1984 • 155 citations

Relationships in the Drosophila obscura species group, inferred from mitochondrial cytochrome oxidase II sequences.

1993 • 143 citations

Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophilagenome

2002 • 140 citations

A NEW METHOD FOR THE STUDY OF CHROMOSOME ABERRATIONS AND THE PLOTTING OF CHROMOSOME MAPS IN DROSOPHILA MELANOGASTER

1934 • 139 citations

Mobile Elements and the Genesis of Microsatellites in Dipterans

2001 • 131 citations

The fourth chromosome of Drosophila melanogaster : Interspersed euchromatic and heterochromatic domains

2000 • 131 citations

Evolutionary genomics of inversions in Drosophila pseudoobscura : Evidence for epistasis

2003 • 121 citations

Relationships within the melanogaster species subgroup of the genus Drosophila (Sophophora)

1984 • 121 citations

EVIDENCE FOR EXTENSIVE GENETIC DIFFERENTIATION BETWEEN THE SEX-RATIO AND THE STANDARD ARRANGEMENT OF DROSOPHILA PSEUDOOBSCURA AND D. PERSIMILIS AND IDENTIFICATION OF HYBRID STERILITY FACTORS

1983 • 119 citations

Ratios of Radical to Conservative Amino Acid Replacement are Affected by Mutational and Compositional Factors and May Not Be Indicative of Positive Darwinian Selection

2002 • 118 citations

Isolation and analysis of the breakpoint sequences of chromosome inversion In(3L)Payne in Drosophila melanogaster.

1994 • 115 citations

Intrachromosomal rearrangements mediated by hobo transposons in Drosophila melanogaster.

1988 • 109 citations

Gene synteny and evolution of genome architecture in trypanosomatids

2003 • 102 citations

The distribution of transposable elements within and between chromosomes in a population ofDrosophila melanogaster. II. Inferences on the nature of selection against elements

1992 • 102 citations

Conservation of regulatory elements between two species of Drosophila

2003 • 98 citations

Selection of new inversions in multi-locus genetic systems

1973 • 91 citations

Mobile elements and chromosomal evolution in the virilis group of Drosophila

2000 • 85 citations

Assessing the Quality of the DNA Sequence from The Human Genome Project

1999 • 75 citations

The Foldback-like Transposon Galileo Is Involved in the Generation of Two Different Natural Chromosomal Inversions of Drosophila buzzatii

2003 • 75 citations

SALIVARY GLAND CHROMOSOMES IN THE TWO RACES OF DROSOPHILA PSEUDOOBSCURA

1935 • 71 citations

The comparative genetics ofDrosophila pseudoobscura andD. melanogaster

1937 • 68 citations

The role of the transposable element hobo in the origin of endemic inversions in wild populations of Drosophila melanogaster

1992 • 66 citations

Cytogenetics: The Chromosome in Division, Inheritance, and Evolution

1980 • 65 citations

Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura

2004 • 65 citations

CHROMOSOME VARIATION IN DROSOPHILA ATHABASCA

1946 • 64 citations

A “Double Adaptor” Method for Improved Shotgun Library Construction

1996 • 60 citations

Chromosomal Homology and Molecular Organization of Muller's Elements D and E in the Drosophila repleta Species Group

1997 • 58 citations

Are Radical and Conservative Substitution Rates Useful Statistics in Molecular Evolution?

2003 • 51 citations

OBSERVATIONS AND EXPERIMENTS ON NATURAL SELECTION IN DROSOPHILA

2010 • 50 citations

P1 clones from Drosophila melanogaster as markers to study the chromosomal evolution of Muller's A element in two species of the obscura group of Drosophila

1995 • 44 citations

Genetic instability in Drosophila melanogaster mediated by hobo transposable elements.

1993 • 41 citations

Structure of chromosomal rearrangements induced by the FB transposable element in Drosophila

1984 • 41 citations

Molecular characterization of the breakpoints of an inversion fixed between Drosophila melanogaster and D. subobscura.

1995 • 33 citations

Hobo transposons causing chromosomal breakpoints

1998 • 31 citations

DNA sequence analysis of a Drosophila foldback transposable element rearrangement

1982 • 21 citations

Are chromosomal inversions induced by transposable elements? A paradigm from the malaria mosquito Anopheles gambiae.

1999 • 16 citations

MISCELLANEOUS: Contributions to the Genetics, Taxonomy, and Ecology of Drosophila pesudoobscura and its Relatives. T<scp>h</scp>. D<scp>obzhansky</scp> and C<scp>arl</scp> E<scp>pling</scp>

1944 • 13 citations