Principles of MicroRNA–Target Recognition

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

The functions of animal microRNAs

2004 • 10,392 citations

Prediction of Mammalian MicroRNA Targets

2003 • 5,070 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

Identification of Novel Genes Coding for Small Expressed RNAs

2001 • 4,834 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

Human MicroRNA Targets

2004 • 3,702 citations

MicroRNAs Modulate Hematopoietic Lineage Differentiation

2003 • 3,241 citations

MicroRNA targets in Drosophila

2003 • 3,228 citations

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

2001 • 2,623 citations

Argonaute2 Is the Catalytic Engine of Mammalian RNAi

2004 • 2,620 citations

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

2000 • 2,422 citations

Fast and effective prediction of microRNA/target duplexes

2004 • 2,357 citations

Prediction of Plant MicroRNA Targets

2002 • 2,239 citations

Computational Identification of Plant MicroRNAs and Their Targets, Including a Stress-Induced miRNA

2004 • 2,226 citations

A pancreatic islet-specific microRNA regulates insulin secretion

2004 • 2,054 citations

bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

2003 • 2,012 citations

Dicer is essential for mouse development

2003 • 1,896 citations

Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing

2001 • 1,847 citations

Role of MicroRNAs in Plant and Animal Development

2003 • 1,765 citations

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

2001 • 1,761 citations

MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 • 1,680 citations

Specificity of microRNA target selection in translational repression

2004 • 1,631 citations

Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

2002 • 1,426 citations

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

2004 • 1,406 citations

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

2004 • 1,254 citations

siRNAs can function as miRNAs

2003 • 1,252 citations

The microRNAs ofCaenorhabditis elegans

2003 • 1,232 citations

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

2003 • 1,003 citations

The Small RNA Profile during Drosophila melanogaster Development

2003 • 955 citations

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

2004 • 831 citations

Identification of Drosophila MicroRNA Targets

2003 • 792 citations

A combined computational-experimental approach predicts human microRNA targets

2004 • 776 citations

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

2000 • 761 citations

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

2003 • 756 citations

Computational identification of DrosophilamicroRNA genes

2003 • 724 citations

MicroRNAs and Other Tiny Endogenous RNAs in C. elegans

2003 • 702 citations

Evidence that microRNA precursors, unlike other non-coding RNAs, have lower folding free energies than random sequences

2004 • 526 citations

AVID: A Global Alignment Program

2002 • 496 citations

The microRNA-producing enzyme Dicer1 is essential for zebrafish development

2003 • 460 citations

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR

2004 • 441 citations

Small RNAs with Imperfect Match to Endogenous mRNA Repress Translation

2003 • 430 citations

The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 Controls Developmental Time and Is Regulated by MicroRNAs

2003 • 370 citations

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

2003 • 354 citations

Computational identification of microRNA targets

2004 • 308 citations

microRNAs: Runts of the Genome Assert Themselves

2003 • 266 citations

A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.

1996 • 235 citations

Common logic of transcription factor and microRNA action

2004 • 199 citations

Predicting and validating microRNA targets.

2004 • 143 citations

The Bearded box, a novel 3′ UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression

1997 • 118 citations