Nucleotide excision repair: From E. coli to man

DNA Repair and Mutagenesis

2006 • 4,725 citations

DNA repair and mutagenesis

1996 • 2,289 citations

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

REPAIR OF OXIDATIVE DAMAGE TO DNA: Enzymology and Biology

1994 • 1,435 citations

DNA EXCISION REPAIR

1996 • 1,127 citations

The Genetic Basis of Human Cancer

1997 • 1,113 citations

Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

1997 • 1,108 citations

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1964 • 987 citations

DNA REPAIR ENZYMES

1988 • 822 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

Mutagenesis by 8-oxoguanine: an enemy within

1993 • 805 citations

RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12

1964 • 710 citations

ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

1992 • 707 citations

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

1990 • 687 citations

A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

1983 • 618 citations

Reactions and significance of cytochrome P-450 enzymes

1991 • 596 citations

Cloning and characterization of hOGG1 , a human homolog of the OGG1 gene of Saccharomyces cerevisiae

1997 • 586 citations

Mechanisms of DNA Excision Repair

1994 • 560 citations

Evidence for repair-replication of ultraviolet damaged DNA in bacteria

1964 • 510 citations

XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair

1994 • 481 citations

Reconstitution of Human DNA Repair Excision Nuclease in a Highly Defined System

1995 • 460 citations

Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.

1992 • 428 citations

DNA adducts : identification and biological significance

1994 • 401 citations

RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

1995 • 387 citations

DNA repair protects against cutaneous and internal neoplasia: evidence from xeroderma pigmentosum

1984 • 382 citations

Expression of Wild-type p53 Is Required for Efficient Global Genomic Nucleotide Excision Repair in UV-irradiated Human Fibroblasts

1997 • 365 citations

Reaction Mechanism of Human DNA Repair Excision Nuclease

1996 • 362 citations

In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

1997 • 358 citations

Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.

1990 • 347 citations

Chromatin Assembly Coupled to DNA Repair: A New Role for Chromatin Assembly Factor I

1996 • 333 citations

Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.

1991 • 313 citations

The Genetic Basis of Human Cancer

1998 • 305 citations

DNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE

1993 • 301 citations

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA

1993 • 295 citations

Cigarette smoking induces an increase in oxidative DNA damage, 8- hydroxydeoxyguanosine, in a central site of the human lung

1997 • 289 citations

An Interaction between the DNA Repair Factor XPA and Replication Protein A Appears Essential for Nucleotide Excision Repair

1995 • 257 citations

Reconstitution of Yeast Nucleotide Excision Repair with Purified Rad Proteins, Replication Protein A, and Transcription Factor TFIIH

1995 • 242 citations

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein

1997 • 233 citations

On diseases of the skin, including the exanthemata

1866 • 229 citations

Purification of PCNA as a nucleotide excision repair protein

1992 • 228 citations

Inactivation of OGG1 increases the incidence of G · C→T · A transversions in Saccharomyces cerevisiae : evidence for endogenous oxidative damage to DNA in eukaryotic cells

1997 • 217 citations

Human DNA Repair Excision Nuclease

1995 • 216 citations

Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response

1997 • 210 citations

Recognition and Repair of Compound DNA Lesions (Base Damage and Mismatch) by Human Mismatch Repair and Excision Repair Systems

1997 • 198 citations

Replication Protein A Confers Structure-specific Endonuclease Activities to the XPF-ERCC1 and XPG Subunits of Human DNA Repair Excision Nuclease

1996 • 187 citations

A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA

1989 • 177 citations

Assembly, subunit composition, and footprint of human DNA repair excision nuclease

1998 • 169 citations

Reconstitution of Human Excision Nuclease with Recombinant XPF-ERCC1 Complex

1997 • 168 citations

Overproduction, Purification, and Characterization of the XPC Subunit of the Human DNA Repair Excision Nuclease

1996 • 165 citations

Characterization of Reaction Intermediates of Human Excision Repair Nuclease

1997 • 162 citations

The Non-catalytic Function of XPG Protein during Dual Incision in Human Nucleotide Excision Repair

1997 • 158 citations

Molecular Matchmakers

1993 • 153 citations

Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I.

1992 • 151 citations

Carcinogens enhance survival of UV-irradiated simian virus 40 in treated monkey kidney cells: induction of a recovery pathway?

1978 • 147 citations

Three Unusual Repair Deficiencies Associated with Transcription Factor BTF2(TFIIH): Evidence for the Existence of a Transcription Syndrome

1994 • 144 citations

The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters

1982 • 140 citations

DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes.

1993 • 131 citations

Replication of Damaged DNA and the Molecular Mechanism of Ultraviolet Light Mutagenesis

1993 • 124 citations

Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues.

1992 • 123 citations

Formation and enzymatic properties of the UvrB.DNA complex.

1990 • 119 citations

An Affinity of Human Replication Protein A for Ultraviolet-damaged DNA

1996 • 114 citations

Cockayne syndrome: defective repair of transcription?

1997 • 113 citations

Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner

1997 • 106 citations

Xeroderma pigmentosum complementation group G associated with Cockayne syndrome.

1993 • 105 citations

Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans

1997 • 101 citations

DNA Polymerases Required for Repair of UV-Induced Damage in Saccharomyces cerevisiae

1995 • 101 citations

Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro

1996 • 99 citations

Determination of minimum substrate size for human excinuclease.

1994 • 91 citations

Binding of human single-stranded DNA binding protein to DNA damaged by the anticancer drug cis-diamminedichloroplatinum (II).

1992 • 91 citations

Structure and Function of the UvrB Protein

1995 • 82 citations

SOS Response in Mammalian Cells

1985 • 78 citations

Promoter properties and negative regulation of the uvrA gene by the LexA represser and its amino-terminal DNA binding domain

1987 • 78 citations

Analysis of UvrABC endonuclease reaction intermediates on cisplatin-damaged DNA using mobility shift gel electrophoresis.

1992 • 77 citations

Induction of only one SOS operon, umuDC, is required for SOS mutagenesis in Escherichia coli

1993 • 75 citations

Electron microscopic study of (A)BC excinuclease

1992 • 75 citations

Acetylaminofluorene bound to different guanines of the sequence -GGCGCC- is excised with different efficiencies by the UvrABC excision nuclease in a pattern not correlated to the potency of mutation induction.

1990 • 70 citations

Fludarabine triphosphate inhibits nucleotide excision repair of cisplatin-induced DNA adducts in vitro.

1997 • 70 citations

LexA protein inhibits transcription of the E. coli uvrA gene in vitro

1982 • 67 citations

Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes.

1997 • 67 citations

A conserved 5‘ to 3‘ exonuclease activity in the yeast and human nucleotide excision repair proteins RAD2 and XPG.

1994 • 56 citations

Nucleotide Excision Repair in the Third Kingdom

1998 • 56 citations

DNA damage caused by oxidation, deamination, ultraviolet radiation and photoexcited psoralens.

1994 • 46 citations

Leading versus lagging strand mutagenesis induced by 7,8-dihydro-8-oxo-2′-deoxyguanosine in Escherichia coli

1997 • 44 citations

The repair patch ofE.coli(A)BC excinuclease

1990 • 39 citations

Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6-10 Have Normal General Excision Repair Activity

1997 • 36 citations

Reconstitution of nucleotide excision nuclease with UvrA and UvrB proteins from Escherichia coli and UvrC protein from Bacillus subtilis.

1990 • 36 citations

Sequence-dependent modulation of nucleotide excision repair: the efficiency of the incision reaction is inversely correlated with the stability of the pre-incision UvrB-DNA complex

1997 • 26 citations

Characterization of dinY, a new Escherichia coli DNA repair gene whose products are damage inducible even in a lexA(Def) background

1993 • 23 citations

Rodent complementation group 8 (ERCC8) corresponds to Cockayne syndrome complementation group A

1996 • 22 citations

Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes

1998 • 22 citations

Inducible nucleotide excision repair (NER) of UV-induced cyclobutane pyrimidine dimers in the cell cycle of the budding yeast Saccharomyces cerevisiae : evidence that inducible NER is confined to the G1 phase of the mitotic cell cycle

1997 • 13 citations

Binding and Incision Activities of UvrABC Excinuclease on Slipped DNA Intermediates that Generate Frameshift Mutations

1996 • 12 citations