A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

Superoxide dismutases

1989 • 953 citations

DNA REPAIR ENZYMES

1988 • 822 citations

A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

1983 • 618 citations

THREE LOCI IN ESCHERICHIA COLI K-12 THAT CONTROL THE EXCISION OF PYRIMIDINE DIMERS AND CERTAIN OTHER MUTAGEN PRODUCTS FROM DNA

1966 • 566 citations

DNA Repair and Genetic Recombination: Studies on Mutants of Escherichia coli Defective in These Processes

1966 • 554 citations

Inducible repair of oxidative DNA damage in Escherichia coli

1983 • 415 citations

Endonuclease IV (nfo) mutant of Escherichia coli

1986 • 397 citations

Regulation of the synthesis of superoxide dismutase in Escherichia coli. Induction by methyl viologen.

1977 • 396 citations

Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage.

1984 • 365 citations

Bimodal pattern of killing of DNA-repair-defective or anoxically grown Escherichia coli by hydrogen peroxide

1986 • 349 citations

DNA N-glycosylases and UV repair

1980 • 307 citations

Apurinic sites as mutagenic intermediates

1985 • 283 citations

Ap endonucleases and dna glycosylases that recognize oxidative dna damage

1988 • 254 citations

DNA glycosylase activities for thymine residues damaged by ring saturation, fragmentation, or ring contraction are functions of endonuclease III in Escherichia coli.

1984 • 249 citations

Escherichia coli endonuclease III is not an endonuclease but a β-elimination catalyst

1987 • 247 citations

A global response induced in Escherichia coli by redox-cycling agents overlaps with that induced by peroxide stress

1989 • 240 citations

A new endonuclease from Escherichia coli acting at apurinic sites in DNA.

1977 • 225 citations

Escherichia coli xth mutants are hypersensitive to hydrogen peroxide

1983 • 223 citations

Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.

1985 • 223 citations

Endonuclease III is an iron-sulfur protein

1989 • 218 citations

The (A)BC excinuclease of Escherichia coli has only the UvrB and UvrC subunits in the incision complex.

1989 • 204 citations

Characterization of the Escherichia coli x-ray endonuclease, endonuclease III

1983 • 202 citations

Molecular Models for DNA Damaged by Photoreaction

1985 • 191 citations

Homogeneous Escherichia coli endonuclease IV. Characterization of an enzyme that recognizes oxidative damage in DNA.

1988 • 183 citations

Thymine dimers bend DNA.

1988 • 172 citations

The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.

1988 • 166 citations

Mechanism of action of Escherichia coli endonuclease III

1987 • 162 citations

Alternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.

1988 • 139 citations

Regulation of the synthesis of catalase and peroxidase in Escherichia coli.

1978 • 132 citations

The mechanisms of action ofE.coliendonuclease III and T4 UV endonuclease (endonuclease V) at AP sites

1988 • 121 citations

Escherichia coli proteins inducible by oxidative stress mediated by the superoxide radical

1989 • 118 citations

A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines.

1987 • 110 citations

Structural studies of the O6meG.cntdot.C interaction in the d(C-G-C-G-A-A-T-T-C-O6meG-C-G) duplex

1986 • 104 citations

Deletions of bases in one strand of duplex DNA, in contrast to single-base mismatches, produce highly kinked molecules: possible relevance to the folding of single-stranded nucleic acids.

1989 • 100 citations

Repair of O6-Methylguanine by ABC Excinuclease of Escherichia coli in vitro

1989 • 94 citations

Yeast DNA 3′-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics.

1988 • 91 citations

Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts.

1988 • 82 citations

Binding of Escherichia coli DNA photolyase to UV-irradiated DNA

1985 • 73 citations

Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease

1987 • 72 citations

Yeast DNA diesterase for 3′-fragments of deoxyribose: purification and physical properties of a repair enzyme for oxidative DNA damage.

1988 • 67 citations

NMR studies of abasic sites in DNA duplexes: deoxyadenosine stacks into the helix opposite acyclic lesions

1989 • 59 citations

Structure of a Psoralen Cross-Linked DNA in Solution by Nuclear Magnetic Resonance

1987 • 58 citations

Isolation of gene fusions (soi::lacZ) inducible by oxidative stress in Escherichia coli.

1988 • 53 citations

Yeast redoxyendonuclease, a DNA repair enzyme similar to Escherichia coli endonuclease III

1988 • 48 citations

Excision repair of O⁶-methylguanine synthesized at the rat H-ras N-methyl-N-nitrosourea activation site and introduced into Escherichia coli

1989 • 47 citations

Activities and incision patterns of ABC excinuclease on modified DNA containing single-base mismatches and extrahelical bases.

1986 • 45 citations

Incision of damaged versus nondamaged DNA by theEscherichia coliUvrABC proteins

1988 • 39 citations

Role of exonuclease III and endonuclease IV in repair of pyrimidine dimers initiated by bacteriophage T4 pyrimidine dimer-DNA glycosylase

1989 • 38 citations

Modeling and molecular mechanical studies of the cis-thymine glycol radiation damage lesion in DNA

1987 • 38 citations

Multiple DNA repair activities for 3'-deoxyribose fragments inEscherichia coli

1989 • 37 citations

Phased psoralen cross-links do not bend the DNA double helix

1988 • 34 citations

Evidence for structural deformation of the DNA helix by a psoralen diadduct but not by a monoadduct

1988 • 21 citations