The Legionella pneumophila prp locus; required during infection of macrophages and amoebae

Conjugative Transfer by the Virulence System of Legionella pneumophila

1998 • 709 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila

1979 • 655 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome

1998 • 530 citations

Expression of Legionella pneumophila Virulence Traits in Response to Growth Conditions

1998 • 361 citations

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

1998 • 360 citations

Legionella pneumophila Utilizes the Same Genes To Multiply within Acanthamoeba castellanii and Human Macrophages

1999 • 299 citations

A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection

1989 • 254 citations

Invasion of Protozoa by Legionella pneumophila and Its Role in Bacterial Ecology and Pathogenesis

1998 • 245 citations

Utilization of similar mechanisms by Legionella pneumophila to parasitize two evolutionarily distant host cells, mammalian macrophages and protozoa

1997 • 236 citations

Surface-Associated Hsp60 Chaperonin of Legionella pneumophila Mediates Invasion in a HeLa Cell Model

1998 • 232 citations

Evidence for pore‐forming ability by Legionella pneumophila

1998 • 227 citations

Expression of Multiple Pili by Legionella pneumophila : Identification and Characterization of a Type IV Pilin Gene and Its Role in Adherence to Mammalian and Protozoan Cells

1998 • 190 citations

Natural Competence for DNA Transformation by Legionella pneumophila and Its Association with Expression of Type IV Pili

1999 • 187 citations

Phenotypic modulation by Legionella pneumophila upon infection of macrophages

1993 • 170 citations

Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes.

1990 • 157 citations

Apoptosis in Macrophages and Alveolar Epithelial Cells during Early Stages of Infection byLegionella pneumophilaand Its Role in Cytopathogenicity

1999 • 132 citations

Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells

1995 • 124 citations

Identification and Temperature Regulation of Legionella pneumophila Genes Involved in Type IV Pilus Biogenesis and Type II Protein Secretion

1998 • 111 citations

The use of differential display‐PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages

1996 • 110 citations

Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon

1997 • 106 citations

Treatment of alveolar macrophages with cytochalasin D inhibits uptake and subsequent growth of Legionella pneumophila

1986 • 101 citations

Identification of a Gal/GalNAc Lectin in the Protozoan Hartmannella vermiformis as a Potential Receptor for Attachment and Invasion by the Legionnaires' Disease Bacterium

1997 • 101 citations

Identification of Macrophage-Specific Infectivity Loci ( mil ) of Legionella pneumophila That Are Not Required for Infectivity of Protozoa

1998 • 91 citations

Transcriptional regulation of the macrophage‐induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant

1997 • 90 citations

Elevated levels of Legionella pneumophila stress protein Hsp60 early in infection of human monocytes and L929 cells correlate with virulence

1996 • 88 citations

Fatal attraction of mammalian cells to Legionella pneumophila

1998 • 84 citations

An iron- and fur-repressed Legionella pneumophila gene that promotes intracellular infection and encodes a protein with similarity to the Escherichia coli aerobactin synthetases

1997 • 80 citations

Heterogeneity in the Attachment and Uptake Mechanisms of the Legionnaires’ Disease Bacterium, Legionella pneumophila , by Protozoan Hosts

1998 • 78 citations

Legionella pneumophila Replicates within Rat Alveolar Epithelial Cells

1993 • 73 citations

Infectivity of Legionella pneumophila mip mutant for alveolar epithelial cells

1995 • 71 citations

Induced Expression of the Legionella pneumophila Gene Encoding a 20-Kilodalton Protein during Intracellular Infection

1998 • 65 citations

Cloning and molecular characterization of a Legionella pneumophila gene induced by intracellular infection and by various in vitro stress conditions

1994 • 62 citations

Different fates ofLegionella pneumophila pmiandmilmutants within macrophages and alveolar epithelial cells

1998 • 60 citations

Legionella pneumophilakills human phagocytes but not protozoan host cells by inducing apoptotic cell death

1998 • 55 citations

Intrapulmonary Hartmannella vermiformis: a potential niche for Legionella pneumophila replication in a murine model of legionellosis

1997 • 53 citations

A sigma E dependent operon subject to catabolite repression during sporulation in Bacillus subtilis

1996 • 47 citations

Identification of Putative Cytoskeletal Protein Homologues in the Protozoan Host Hartmannella vermiformis as Substrates for Induced Tyrosine Phosphatase Activity upon Attachment to the Legionnaires' Disease Bacterium, Legionella pneumophila

1998 • 42 citations

Opsonin-independent adherence and intracellular development of Legionella pneumophila within U-937 cells

1993 • 41 citations

De novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells

1996 • 38 citations

Signal Transduction in the Protozoan Host Hartmannella vermiformis upon Attachment and Invasion by Legionella micdadei

1998 • 38 citations

Invasion of mammalian and protozoan cells by Legionella pneumophila

1998 • 30 citations

Epidemiological and Environmental Investigations of Legionella pneumophila Infection in Cattle and Case Report of Fatal Pneumonia in a Calf

1998 • 23 citations

Phenotypic modulation by intracellular bacterial pathogens

1999 • 23 citations

Probing the microenvironment of intracellular bacterial pathogens

1999 • 21 citations

PhoA gene fusions in Legionella pneumophila generated in vivo using a new transposon, MudphoA

1992 • 20 citations

Legionella pneumophila: factors involved in the route and response to an intracellular niche.

1993 • 7 citations

Construction of an alkaline phosphatase fusion-generating transposon, mTn10phoA

1996 • 6 citations

Phenotypic modulation by intracellular bacterial pathogens

1999 • 1 citations