The use of differential display‐PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages

Basic local alignment search tool

1990 • 87,358 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction

1992 • 5,105 citations

Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae.

1980 • 979 citations

A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.

1989 • 943 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

1995 • 680 citations

Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

1980 • 648 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1993 • 633 citations

A Salmonella Locus that Controls Resistance to Microbicidal Proteins from Phagocytic Cells

1989 • 556 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes.

1992 • 441 citations

Induction of Salmonella Stress Proteins Upon Infection of Macrophages

1990 • 429 citations

An Outbreak of Legionnaires' Disease Associated with a Contaminated Air-Conditioning Cooling Tower

1980 • 413 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

Phagocytosis of the legionnaires' disease bacterium (legionella pneumophila) occurs by a novel mechanism: Engulfment within a Pseudopod coil

1984 • 317 citations

Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages.

1992 • 310 citations

Current views on the relationships between amoebae, legionellae and man.

1986 • 298 citations

Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors.

1987 • 287 citations

Legionella: Current Status and Emerging Perspectives

1993 • 272 citations

A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection

1989 • 254 citations

Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene

1994 • 248 citations

DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity

1989 • 212 citations

The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum

1996 • 200 citations

The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages

1994 • 182 citations

Isolation of the Legionnaires' Disease Bacterium from Environmental Samples

1979 • 178 citations

Phenotypic modulation by Legionella pneumophila upon infection of macrophages

1993 • 170 citations

A Salmonella typhimurium virulence protein is similar to a Yersinia enterocolitica invasion protein and a bacteriophage lambda outer membrane protein

1991 • 160 citations

Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophila

1995 • 157 citations

Analysis of proteins synthesized by Salmonella typhimurium during growth within a host macrophage

1993 • 156 citations

Interactions between Naegleria fowleri and Legionella pneumophila

1985 • 148 citations

Association of shower use with Legionnaires' disease. Possible role of amoebae

1990 • 148 citations

Induction of Mycobacterium avium gene expression following phagocytosis by human macrophages

1994 • 136 citations

Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells

1995 • 124 citations

Comparison of guinea pig and protozoan models for determining virulence of Legionella species

1986 • 123 citations

Stress-inducible gene of Salmonella typhimurium identified by arbitrarily primed PCR of RNA.

1994 • 97 citations

Effects of cytochalasin D and methylamine on intracellular growth of Legionella pneumophila in amoebae and human monocyte-like cells

1991 • 91 citations

Legionella wadsworthii Species Nova: A Cause of Human Pneumonia

1982 • 83 citations

Characterization of an Axenic Strain of Hartmannella vermiformis Obtained from an Investigation of Nosocomial Legionellosis

1990 • 83 citations

Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection

1996 • 80 citations

Association of flagellum expression and intracellular growth of Legionella pneumophila

1995 • 77 citations

EPIDEMIOLOGIC ASPECTS OF LEGIONELLOSIS

1979 • 76 citations

Protein expression by the protozoan Hartmannella vermiformis upon contact with its bacterial parasite Legionella pneumophila

1994 • 74 citations

Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity.

1995 • 73 citations

Cloning and molecular characterization of a Legionella pneumophila gene induced by intracellular infection and by various in vitro stress conditions

1994 • 62 citations

Site-specific mutagenesis inLegionella pneumophilaby allelic exchange using counterselectable ColE1 vectors

1988 • 35 citations

Formation of the Legionella pneumophila replicative phagosome.

1993 • 33 citations

Analysis of Haemophilus influenzae type b lipooligosaccharide‐synthesis genes that assemble or expose a 2‐keto‐3‐deoxyoctulosonic acid epitope

1991 • 30 citations

Identification of Legionella pneumophila promoters regulated by the macrophage intracellular environment.

1993 • 29 citations

Shuttle mutagenesis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity

1994 • 21 citations

PhoA gene fusions in Legionella pneumophila generated in vivo using a new transposon, MudphoA

1992 • 20 citations

Surface morphology of arsenic implanted silicon dioxide observed by atomic force microscopy

1994 • 15 citations

Growth of the Pittsburgh Pneumonia Agent in Animal Cell Cultures

1981 • 15 citations