Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Legionnaires' Disease

1977 • 1,199 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae.

1980 • 979 citations

Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5

1982 • 936 citations

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1993 • 802 citations

Specific incorporation of cyclophilin A into HIV-1 virions

1994 • 736 citations

A wide-host-range suicide vector for improving reverse genetics in Gram-negative bacteria: inactivation of the blaA gene of Yersinia enterocolitica

1991 • 692 citations

Selection of Bacterial Virulence Genes That Are Specifically Induced in Host Tissues

1993 • 671 citations

Atomic Structure of FKBP-FK506, an Immunophilin-Immunosuppressant Complex

1991 • 641 citations

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1993 • 633 citations

Trojan Horses of the microbial world: protozoa and the survival of bacterial pathogens in the environment

1994 • 415 citations

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages

1993 • 357 citations

Peptidylproline cis‐trans‐isomerases: immunophilins

1993 • 349 citations

Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans-isomerase.

1991 • 313 citations

Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages.

1992 • 310 citations

The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.

1994 • 305 citations

Solution Structure of FKBP, a Rotamase Enzyme and Receptor for FK506 and Rapamycin

1991 • 302 citations

Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages.

1992 • 272 citations

Broad-host-range vectors for delivery of TnphoA: use in genetic analysis of secreted virulence determinants of Vibrio cholerae

1989 • 257 citations

A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection

1989 • 254 citations

Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene

1994 • 248 citations

Legionnaires disease: historical perspective

1988 • 238 citations

DNA sequence of mip, a Legionella pneumophila gene associated with macrophage infectivity

1989 • 212 citations

Confirmation of the existence of a third family among peptidyl‐prolyl cis/trans isomerases Amino acid sequence and recombinant production of parvulin

1994 • 190 citations

The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages

1994 • 182 citations

Mip protein of Legionella pneumophila exhibits peptidyl‐prolyl‐cis/trans isomerase (PPIase) activity

1992 • 182 citations

Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.

1994 • 162 citations

A Mutation in the mip Gene Results in an Attenuation of Legionella pneumophila Virulence

1990 • 155 citations

A novel peptidyl‐prolyl cisltrans isomerase from Escherichia coli

1994 • 150 citations

Cyclophilin 20 Is Involved in Mitochondrial Protein Folding in Cooperation with Molecular Chaperones Hsp70 and Hsp60

1995 • 147 citations

Solution structure of the major binding protein for the immunosuppressant FK506

1991 • 146 citations

Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex.

1992 • 126 citations

Virulence factors of the family Legionellaceae

1992 • 124 citations

Tn1721 derivatives for transposon mutagenesis, restriction mapping and nucleotide sequence analysis

1986 • 120 citations

Chlamydia trachomatis Mip‐like protein has peptidylprolyl cis/trans isomerase activity that is inhibited by FK506 and rapamycin and is implicated in initiation of chlamydial infection

1993 • 102 citations

A comparison of virulence of two strains ofLegionella pneumophilabased on experimental aerosol infection of guinea-pigs

1985 • 102 citations

Immunophilins: structure—function relationship and possible role in microbial pathogenicity

1993 • 96 citations

A new family of peptidyl-prolyl isomerases

1995 • 95 citations

Escherichia coli and other species of the enterobacteriaceae encode a protein similar to the family of Mip-like FK506-binding proteins

1995 • 92 citations

Über Peptidyl‐Prolyl‐cis/trans‐Isomerasen und ihre Effektoren

1994 • 54 citations

Sequence determination and mutational analysis of the lly locus of Legionella pneumophila

1994 • 51 citations

Studies on the uptake and intracellular replication of Legionella pneumophila in protozoa and in macrophage-like cells

1994 • 46 citations

Nucleotide sequence analysis of the Legionella micdadei mip gene, encoding a 30-kilodalton analog of the Legionella pneumophila Mip protein

1991 • 46 citations

Characterization of Mip proteins ofLegionella pneumophila

1994 • 46 citations

A homodimer represents an active species of the peptidyl‐prolyl cis/trans isomerase FKBP25mem from Legionella pneumophila

1994 • 37 citations

Cloning, genetic analysis, and nucleotide sequence of a determinant coding for a 19-kilodalton peptidoglycan-associated protein (Ppl) of Legionella pneumophila

1991 • 29 citations

Detection of mip-like sequences and mip-related proteins within the family Rickettsiaceae

1995 • 26 citations

Phagocytosis and Intracellular Biology of Legionella Pneumophila

1988 • 18 citations