mtv shapes the activity gradient of the Dpp morphogen through regulation of thickveins

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Dual Roles for Patched in Sequestering and Transducing Hedgehog

1996 • 889 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

TheDrosophilamushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells

1997 • 783 citations

Developmental Compartmentalisation of the Wing Disk of Drosophila

1973 • 770 citations

MADR2 Is a Substrate of the TGFβ Receptor and Its Phosphorylation Is Required for Nuclear Accumulation and Signaling

1996 • 740 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

1994 • 624 citations

The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal

1996 • 591 citations

Morphogens, Compartments, and Pattern: Lessons from Drosophila?

1996 • 559 citations

Lakes Beneath the Antarctic Ice Sheet

1973 • 555 citations

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

1995 • 489 citations

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1996 • 474 citations

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

1997 • 426 citations

Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing

1997 • 416 citations

Role of the Drosophila patched gene in positional signalling

1991 • 414 citations

Hedgehog Creates a Gradient of DPP Activity in Drosophila Wing Imaginal Discs

2000 • 402 citations

The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation

1998 • 390 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development

1995 • 315 citations

Protein kinase A and hedgehog signaling in drosophila limb development

1995 • 310 citations

A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing

1997 • 300 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis

1995 • 246 citations

cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in drosophila imaginal discs

1995 • 236 citations

A gene complex acting downstream of dpp in Drosophila wing morphogenesis

1996 • 232 citations

Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila

1998 • 218 citations

The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development.

1994 • 212 citations

Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless

1996 • 206 citations

The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors

1998 • 205 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex

1998 • 173 citations

Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning

1995 • 160 citations

Hedgehog activity, independent of Decapentaplegic, participates in wing disc patterning

1997 • 155 citations

Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed.

1995 • 134 citations

The Drosophila saxophone Gene: a Serine-Threonine Kinase Receptor of the TGF-β Superfamily

1994 • 131 citations

The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing

1997 • 127 citations

Formation of morphogen gradients in the Drosophila wing

1999 • 115 citations

Cells’ Perception of Position in a Concentration Gradient

1998 • 107 citations

Interplay of Signal Mediators of Decapentaplegic (Dpp): Molecular Characterization of Mothers against dpp, Medea, and Daughters against dpp

1998 • 100 citations

Function of the spalt/spalt-related gene complex in positioning the veins in the Drosophila wing

2000 • 95 citations

A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

1999 • 90 citations

Behind the Official Optimism, Flawed Projections

1996 • 89 citations

Mothers against dpp participates in a DPP/TGF-β responsive serine-threonine kinase signal transduction cascade

1997 • 88 citations

Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing

1997 • 75 citations

brakeless is required for lamina targeting of R1-R6 axons in the Drosophila visual system

2000 • 56 citations

Abnormal Turning Behavior in Drosophila Larvae: Identification and Molecular Analysis ofscribbler(sbb)

2000 • 46 citations

brakeless is required for photoreceptor growth-cone targeting in Drosophila

2000 • 45 citations