Expression and activation of matrix metalloproteinase‐2 (MMP‐2) and its co‐localization with membrane‐type 1 matrix metalloproteinase (MT1‐MMP) correlate with melanoma progression

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

1996 • 1,555 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

Regulation of matrix metalloproteinase expression in tumor invasion

1999 • 1,503 citations

Activation mechanisms of matrix metalloproteinases.

1997 • 1,134 citations

Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation

1996 • 741 citations

Matrix metalloproteinases in tumour invasion and metastasis

1999 • 670 citations

Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion and metastasis

1993 • 606 citations

The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A

1998 • 578 citations

Matrix metal loproteinases and the development of cancer

1996 • 569 citations

The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation

1996 • 564 citations

Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

1997 • 419 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2

1993 • 338 citations

Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma.

1996 • 330 citations

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

1995 • 319 citations

Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Binds to the Catalytic Domain of the Cell Surface Receptor, Membrane Type 1-Matrix Metalloproteinase 1 (MT1-MMP)

1998 • 285 citations

Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.

1996 • 278 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasis

1995 • 267 citations

Identification and Characterization of the Fifth Membrane-type Matrix Metalloproteinase MT5-MMP

1999 • 261 citations

The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form

1998 • 228 citations

Expression and Tissue Localization of Membrane-Type 1, 2, and 3 Matrix Metalloproteinases in Human Astrocytic Tumors

1999 • 220 citations

Cell surface activation of progelatinase A (proMMP-2) and cell migration

1998 • 201 citations

Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2.

1998 • 189 citations

Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Human Brain Tumors

1998 • 185 citations

Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas.

1999 • 160 citations

Identification of Cysteine 354 of β-Tubulin as Part of the Binding Site for the A Ring of Colchicine

1996 • 160 citations

Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice

1991 • 158 citations

Tissue Inhibitor of Matrix Metalloproteinase-2 Regulates Matrix Metalloproteinase-2 Activation by Modulation of Membrane-type 1 Matrix Metalloproteinase Activity in High and Low Invasive Melanoma Cell Lines

1999 • 151 citations

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression.

1994 • 150 citations

MATRIX METALLOPROTEINASE-2 (72 kD TYPE IV COLLAGENASE) EXPRESSION OCCURS IN THE EARLY STAGE OF HUMAN MELANOCYTIC TUMOUR PROGRESSION AND MAY HAVE PROGNOSTIC VALUE

1996 • 146 citations

Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin.

1997 • 144 citations

Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma

1998 • 136 citations

Antigen expression of metastasizing and non-metastasizing human melanoma cells xenografted into nude mice

1991 • 124 citations

Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential

1997 • 69 citations

Isolation of a mouse MT2‐MMP gene from a lung cDNA library and identification of its product

1997 • 55 citations

Regulation of matrix metalloproteinases following cellular transformation

1996 • 35 citations

The plasminogen activation system in melanoma cell lines and in melanocytic lesions

1996 • 32 citations

Proteases in cutaneous melanoma

1998 • 28 citations