Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Matrix Metalloproteinases and Other Matrix Proteinases in Relation to Cariology: The Era of ‘Dentin Degradomics'

2015 • 2,211 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules

1997 • 926 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity

1996 • 392 citations

Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells

1989 • 334 citations

The C-terminal Region of Membrane Type Matrix Metalloproteinase Is a Functional Transmembrane Domain Required for Pro-gelatinase A Activation

1995 • 269 citations

Type IV collagenases in invasive tumors

1993 • 256 citations

Matrix metalloproteinase inhibitor BB-94 (batimastat)inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice.

1994 • 254 citations

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.

1994 • 242 citations

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1996 • 232 citations

Extracellular Matrix Binding Properties of Recombinant Fibronectin Type II-like Modules of Human 72-kDa Gelatinase/Type IV Collagenase

1995 • 221 citations

Association of MMP-2 Activation Potential With Metastatic Progression in Human Breast Cancer Cell Lines Independent of MMP-2 Production

1993 • 216 citations

Cell surface binding and activation of gelatinase A induced by expression of membrane‐type‐1‐matrix metalloproteinase (MT1‐MMP)

1996 • 182 citations

Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia.

1993 • 182 citations

Identification of the 170-kDa Melanoma Membrane-bound Gelatinase (Seprase) as a Serine Integral Membrane Protease

1997 • 155 citations

Collagen-induced activation of the M(r) 72,000 type IV collagenase in normal and malignant human fibroblastoid cells.

1992 • 154 citations

Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells.

1992 • 136 citations

A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.

1990 • 125 citations

Proteases Associated with Invadopodia, and Their Role in Degradation of Extracellular Matrix

1996 • 123 citations

A Mechanism for Regulation of Melanoma Invasion

1996 • 117 citations

Complex regulation of membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation by concanavalin A in MDA-MB-231 human breast cancer cells.

1995 • 109 citations

Identification of the 72-kDa (MMP-2) and 92-kDa (MMP-9) gelatinase/type IV collagenase in preparations of laminin and Matrigel.

1993 • 56 citations

Matrix Metalloproteinase Inhibitors: Current Status

1995 • 51 citations

Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy

1994 • 51 citations

Metalloproteinase domain structure, cellular invasion and metastasis

1994 • 42 citations

An in vitro cell invasion assay: Determination of cell surface proteolytic activity that degrades extracellular matrix

1994 • 31 citations

Deleted Work

1955 • 0 citations