Abnormalp53 immunoreactivity and prognosis in node-negative breast carcinomas with long-term follow-up

Histological Grading and Prognosis in Breast Cancer

1957 • 2,897 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.

1983 • 2,066 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Diagnostic Histopathology of the Breast

1988 • 1,083 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Clonal Analysis of Human Colorectal Tumors

1987 • 638 citations

P53 expression in breast cancer

1988 • 612 citations

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

1990 • 607 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

Microvessel quantitation and prognosis in invasive breast carcinoma

1992 • 566 citations

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

1991 • 512 citations

Localization of gene for human p53 tumour antigen to band 17p13

1986 • 498 citations

Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.

1987 • 487 citations

p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors.

1985 • 380 citations

How To Use Prognostic Factors in Axillary Node-Negative Breast Cancer Patients

1990 • 323 citations

Activating Mutations for Transformation by p53 Produce a Gene Product That Forms an hsc70-p53 Complex with an Altered Half-Life

1988 • 298 citations

Genetic basis for p53 overexpression in human breast cancer.

1991 • 287 citations

Maintenance of p53 alterations throughout breast cancer progression.

1991 • 244 citations

p53 expression in colorectal tumors.

1991 • 243 citations

ALLELE LOSS ON SHORT ARM OF CHROMOSOME 17 IN BREAST CANCERS

1988 • 236 citations

Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas.

1991 • 200 citations

Prognostic significance of peritumoral lymphatic and blood vessel invasion in node-negative carcinoma of the breast.

1990 • 154 citations

Relation between p53 overexpression and established prognostic factors in breast cancer.

1991 • 149 citations

Expression of p53 protein in infiltrating and in‐situ breast carcinomas

1991 • 145 citations

p53 gene mRNA expression and chromosome 17p allele loss in breast cancer

1990 • 120 citations

p53 Cellular Tumor Antigen: Analysis of mRNA Levels in Normal Adult Tissues, Embryos, and Tumors

1985 • 117 citations

Tumour suppressor gene products, proliferation, and differentiation markers in lung neuroendocrine neoplasms

1992 • 114 citations

Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen.

1990 • 105 citations

Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.

1991 • 63 citations

DNA ploidy, proliferation, and neu-oncogene protein overexpression in breast carcinoma.

1992 • 37 citations

Abnormal p53 Expression in Lung Neuroendocrine Tumors Diagnostic and Prognostic Implications

1992 • 35 citations

Abnormal p53 Expression in Lung Neuroendocrine Tumors Diagnostic and Prognostic Implications

1992 • 35 citations