Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.

1990 • 978 citations

P53 expression in breast cancer

1988 • 612 citations

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

1990 • 607 citations

Genetic Mechanisms of Tumor Suppression by the Human p53 Gene

1990 • 540 citations

Frequent Mutations in the p53 Tumor Suppressor Gene in Human Leukemia T-Cell Lines

1990 • 296 citations

ALLELE LOSS ON SHORT ARM OF CHROMOSOME 17 IN BREAST CANCERS

1988 • 236 citations

Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumours.

1990 • 165 citations

Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer.

1990 • 127 citations

Characterization of a membrane-associated 3,3',5-triiodo-L-thyronine binding protein by use of monoclonal antibodies

1986 • 41 citations