p53 gene mRNA expression and chromosome 17p allele loss in breast cancer

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Genomic sequencing.

1984 • 8,343 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

A Human Cell Line From a Pleural Effusion Derived From a Breast Carcinoma 2

1973 • 2,431 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Allelotype of Colorectal Carcinomas

1989 • 1,333 citations

Breast Tumor Cell Lines From Pleural Effusions2

1974 • 973 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Establishment and characterization of a cell line of human breast carcinoma origin

1979 • 653 citations

P53 expression in breast cancer

1988 • 612 citations

Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

1984 • 524 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Rearrangement of the p53 gene in human osteogenic sarcomas.

1987 • 489 citations

Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.

1981 • 438 citations

Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53.

1983 • 313 citations

Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus

1982 • 298 citations

ALLELE LOSS ON SHORT ARM OF CHROMOSOME 17 IN BREAST CANCERS

1988 • 236 citations

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells.

1985 • 227 citations

Human p53 gene localized to short arm of chromosome 17

1986 • 222 citations

Overproduction of p53 antigen makes established cells highly tumorigenic

1985 • 217 citations

The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen

1989 • 216 citations

When the products of oncogenes and anti-oncogenes meet

1989 • 213 citations

The cellular oncogene p53 can be activated by mutagenesis

1985 • 181 citations

Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.

1985 • 174 citations

The 5′ region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element.

1985 • 146 citations

A mapped set of DNA markers for human chromosome 15

1988 • 130 citations

Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

1983 • 104 citations

Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation.

1987 • 97 citations

Molecular Cloning and In Vitro Expression of a cDNA Clone for Human Cellular Tumor Antigen p53

1985 • 59 citations

Modulation of the c-myb, c-myc and p53 mRNA and protein levels during induced murine erythroleukemia cell differentiation.

1989 • 57 citations

VNTR (variable number of tandem repeats) markers show loss of chromosome 17p sequences in human colorectal carcinomas

1988 • 35 citations

Deletion of 5′-coding Sequences of the Cellular p53 Gene in Mouse Erythroleukemia: A Novel Mechanism of Oncogene Regulation

1987 • 29 citations

The normal human H-ras1 gene can act as an onco-suppressor.

1988 • 27 citations

p53: Molecular Properties and Biological Activities

1986 • 6 citations

Genomic p53 gene immortalises.

1988 • 2 citations