Follistatin: A Multifunctional Regulatory Protein

Liver Regeneration

1997 • 2,731 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Activin-Binding Protein from Rat Ovary Is Follistatin

1990 • 886 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

Multiple defects and perinatal death in mice deficient in follistatin

1995 • 586 citations

Functional analysis of activins during mammalian development

1995 • 579 citations

The biology of SPARC, a protein that modulates cell‐matrix interactions

1994 • 533 citations

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.

1995 • 510 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

Dual Endocrine Activity of the Testes

1932 • 451 citations

Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone.

1987 • 448 citations

The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4

1997 • 382 citations

SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.

1989 • 375 citations

Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice.

1994 • 369 citations

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors.

1992 • 358 citations

The isolation of polypeptides with FSH suppressing activity from bovine follicular fluid which are structurally different to inhibin

1987 • 349 citations

Vertebrate Embryonic Cells Will Become Nerve Cells Unless Told Otherwise

1997 • 348 citations

Hormonal regulation of apoptosis in early antral follicles: follicle-stimulating hormone as a major survival factor.

1996 • 339 citations

Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle

1993 • 268 citations

Cloning from a mouse osteoblastic cell line of a set of transforming‐growth‐factor‐β1‐regulated genes, one of which seems to encode a follistatin‐related polypeptide

1993 • 264 citations

Follistatin Binds to both Activin and Inhibin through the Common Beta-Subunit

1991 • 258 citations

Visualization of the conservation of synteny between humans and pigs by heterologous chromosomal painting

1995 • 254 citations

Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins

1994 • 252 citations

Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells.

1984 • 251 citations

SPARC is a source of copper-binding peptides that stimulate angiogenesis.

1994 • 247 citations

Inhibin, Activin, and Follistatin: Regulation of Follicle-Stimulating Hormone Messenger Ribonucleic Acid Levels

1989 • 240 citations

Primary structure of the human follistatin precursor and its genomic organization.

1988 • 234 citations

Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

1997 • 229 citations

Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell

1993 • 224 citations

Activin-Binding Protein Is Present in Pituitary*

1991 • 222 citations

Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization.

1993 • 217 citations

Distribution of SPARC in normal and neoplastic human tissue.

1995 • 214 citations

Follistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors

1996 • 213 citations

Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse

1995 • 212 citations

Overexpression of Mouse Follistatin Causes Reproductive Defects in Transgenic Mice

1998 • 210 citations

Activin induces cell death in hepatocytes in vivo and in vitro

1993 • 206 citations

Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes.

1993 • 205 citations

Pregnancy and the Prolactin Family of Hormones: Coordination of Anterior Pituitary, Uterine, and Placental Expression*

1991 • 191 citations

A Novel Role of Follistatin, an Activin-binding Protein, in the Inhibition of Activin Action in Rat Pituitary Cells

1997 • 183 citations

Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells.

1989 • 182 citations

Structural Characterization of Follistatin: A Novel Follicle-Stimulating Hormone Release-Inhibiting Polypeptide from the Gonad

1987 • 176 citations

Activin stimulates Sertoli cell proliferation in a defined period of rat testis development.

1995 • 175 citations

Follistatin Gene Expression in the Ovary and Extragonadal Tissues

1989 • 175 citations

Effects of activin and follicle-stimulating hormone (FSH)-suppressing protein/follistatin on FSH receptors and differentiation of cultured rat granulosa cells.

1992 • 170 citations

Cloning of a New Member of the TGF-β Family: A Putative New Activin βC Chain

1995 • 170 citations

Pituitary follicular cells secrete both vascular endothelial growth factor and follistatin

1989 • 168 citations

Follistatin, an activin-binding protein, associates with heparan sulfate chains of proteoglycans on follicular granulosa cells.

1991 • 167 citations

Recombinant Expression of Human Follistatin with 315 and 288 Amino Acids: Chemical and Biological Comparison with Native Porcine Follistatin*

1991 • 166 citations

Crystal structure of a pair of follistatin-like and EF-hand calcium-binding domains in BM-40

1997 • 164 citations

Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape.

1990 • 164 citations

Agrin-induced specializations contain cytoplasmic, membrane, and extracellular matrix-associated components of the postsynaptic apparatus

1989 • 163 citations

Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC

1995 • 160 citations

The Expression of the Secreted Protein Acidic and Rich in Cysteine (SPARC) Is Associated with the Neoplastic Progression of Human Melanoma

1997 • 160 citations

Inhibition of vascular endothelial cell growth by activin-A.

1993 • 157 citations

Rat follistatin: Gonadal and extragonadal expression and evidence for alternative splicing

1990 • 153 citations

Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis.

1994 • 149 citations

Roles of Inhibins, Activins, and Follistatin in the Female Reproductive System

1996 • 148 citations

Molecular Cloning and Functional Analysis of a New Activin β Subunit: A Dorsal Mesoderm-Inducing Activity in Xenopus

1995 • 147 citations

SPARC antagonizes the effect of basic fibroblast growth factor on the igration of bovine aortic endothelial cells

1992 • 142 citations

Follistatin gene expression in the pituitary: localization in gonadotropes and folliculostellate cells in diestrous rats.

1992 • 140 citations

Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts

1993 • 139 citations

The tissue distribution of activin beta A- and beta B-subunit and follistatin messenger ribonucleic acids suggests multiple sites of action for the activin-follistatin system during human development.

1994 • 136 citations

Characterization of unique binding kinetics of follistatin and activin or inhibin in serum.

1994 • 136 citations

Gonadotropin-releasing hormone regulates follicle-stimulating hormone-beta gene expression through an activin/follistatin autocrine or paracrine loop.

1996 • 134 citations

Modulation of Endothelial Cell Adhesion by Hevin, an Acidic Protein Associated with High Endothelial Venules

1996 • 132 citations

Follistatins: More than follicle-stimulating hormone suppressing proteins

1993 • 131 citations

Molecular Cloning of the Mouse Activin βESubunit Gene

1996 • 129 citations

Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour

1993 • 129 citations

Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain

1994 • 126 citations

Functions of agrin and agrin-related proteins

1993 • 119 citations

The activin-binding protein follistatin regulates autocrine endothelial cell activity and induces angiogenesis.

1997 • 119 citations

Porcine follistatin gene structure supports two forms of mature follistatin produced by alternative splicing

1988 • 117 citations

Testicular Expression of Inhibin and Activin Subunits and Follistatin in the Rat and Human Fetus and Neonate and During Postnatal Development in the Rat¹

1997 • 113 citations

Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids.

1993 • 112 citations

Expression of inhibin beta A and beta B, follistatin and activin-A receptor messenger ribonucleic acids in the rat seminiferous epithelium.

1992 • 109 citations

THE ROLE OF THE RETE OVARII IN MEIOSIS AND FOLLICLE FORMATION IN THE CAT, MINK AND FERRET

1975 • 108 citations

Gonadotropin-releasing hormone pulse frequency regulates expression of pituitary follistatin messenger ribonucleic acid: a mechanism for differential gonadotrope function.

1994 • 104 citations

Exon shuffling and other ways of module exchange

1996 • 102 citations

Building synapses: agrin and dystroglycan stick together

1994 • 100 citations

A single intraportal administration of follistatin accelerates liver regeneration in partially hepatectomized rats

1995 • 99 citations

The effect of bovine activin and follicle-stimulating hormone (FSH) suppressing protein/follistatin on FSH-induced differentiation of rat granulosa cells in vitro

1990 • 99 citations

Isolation and characterization of native activin B.

1992 • 99 citations

The Expression and Regulation ofFollistatinand aFollistatin-likeGene during Avian Somite Compartmentalization and Myogenesis

1996 • 92 citations

Expression of inhibin/activin subunits and follistatin messenger ribonucleic acids and proteins in ovarian follicles and the corpus luteum during the human menstrual cycle.

1993 • 91 citations

SPARC is expressed in renal interstitial fibrosis and in renal vascular injury

1996 • 91 citations

Enhancement of primate oocyte maturation and fertilization in vitro by inhibin A and activin A

1996 • 91 citations

Effects of inhibin-related peptides and oestradiol on androstenedione and progesterone secretion by bovine theca cells in vitro

1995 • 87 citations

Cyclic Changes in Follistatin Messenger Ribonucleic Acid and its Protein in the Rat Ovary During the Estrous Cycle*

1991 • 87 citations

Dynamic regulation of pituitary follistatin messenger ribonucleic acids during the rat estrous cycle.

1994 • 85 citations

Terms of attachment: SPARC and tumorigenesis

1997 • 85 citations

Pituitary follistatin and inhibin subunit messenger ribonucleic acid levels are differentially regulated by local and hormonal factors.

1996 • 83 citations

Immunohistochemical Localization of Activin A and Follistatin in Human Tissues.

1996 • 83 citations

Structure of human osteonectin based upon analysis of cDNA and genomic sequences

1989 • 83 citations

Follistatin modulates activin activity in a cell- and tissue-specific manner.

1993 • 82 citations

Development, validation and application of an ultra-sensitive two-site enzyme immunoassay for human follistatin

1998 • 79 citations

Expression and Localization of Activin Subunits and Follistatins in Tissues from Men with High Grade Prostate Cancer

1997 • 75 citations

Pituitary Follistatin Regulates Activin-Mediated Production of Follicle-Stimulating Hormone during the Rat Estrous Cycle*

1997 • 75 citations

Inhibin and Activin Modulate Human Monocyte Chemotaxis and Human Lymphocyte Interferon-γ Production*

1991 • 74 citations

Local production and action of follistatin in human placenta.

1994 • 74 citations

Local Regulatory Effects of Activin A and Follistatin on Meiotic Maturation of Rat Oocytes

1993 • 73 citations

Regulation of inhibin/activin subunit messenger ribonucleic acids (mRNAs) by activin A and expression of activin receptor mRNAs in cultured human granulosa-luteal cells.

1995 • 72 citations

Expression of α,βA and βB subunits of inhibin or activin and follistatin in rat pancreatic islets

1993 • 72 citations

Localization of follistatin in the rat testis

1998 • 69 citations

Activin-A regulates follistatin secretion from cultured rat anterior pituitary cells.

1993 • 69 citations

Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A.

1996 • 67 citations

Transcription of a quail gene expressed in embryonic retinal cells is shut off sharply at hatching.

1991 • 67 citations

Characterization of a Rat C₆ Glioma‐Secreted Follistatin‐Related Protein (FRP)

1994 • 66 citations

A follistatin-like gene, mac25, may act as a growth suppressor of osteosarcoma cells.

1996 • 65 citations

Immunohistochemical Localization of Follistatin in Rat Tissues.

1991 • 64 citations

Intravenous administration of follistatin: Delivery to the liver and effect on liver regeneration after partial hepatectomy

1996 • 63 citations

A Two-Site Chemiluminescent Assay for Activin-Free Follistatin Reveals That Most Follistatin Circulating in Men and Normal Cycling Women Is in an Activin-Bound State¹

1998 • 63 citations

Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo.

1997 • 61 citations

Production of activin-binding protein by rat granulosa cells in vitro

1991 • 61 citations

The Radioimmunoassay of Follicle-Stimulating Hormone (FSH)-Suppressing Protein (FSP): Stimulation of Bovine Granulosa Cell FSP Secretion by FSH*

1991 • 60 citations

Serum follistatin levels in women: evidence against an endocrine function of ovarian follistatin.

1995 • 60 citations

In situ ligand binding of recombinant human [125I] activin-A and recombinant human [125I]inhibin-A to the adult rat ovary.

1993 • 60 citations

Stimulation of Glucose Production by Activin-A in Isolated Rat Hepatocytes*

1989 • 59 citations

Decay of follicle-stimulating hormone-beta messenger RNA in the presence of transcriptional inhibitors and/or inhibin, activin, or follistatin.

1993 • 59 citations

Follistatin inhibits the mesoderm-inducing activity of activin A and the vegetalizing factor from chicken embryo

1991 • 58 citations

Modulation of Growth of Vascular Smooth Muscle Cells by Activin A

1993 • 58 citations

Follistatin-activin complexes in human serum and follicular fluid differ immunologically and biochemically.

1996 • 58 citations

Opposing Effects of Activin A and Follistatin on Developing Skeletal Muscle Cells

1997 • 58 citations

Steroid Hormones Modulate the Release of Immunoreactive Gonadotropin-Releasing Hormone from Cultured Human Placental Cells*

1990 • 57 citations

Partial characterization of inhibin, activin, and follistatin in the term human placenta.

1994 • 55 citations

Interactions between rhombomeres modulate Krox-20 and follistatin expression in the chick embryo hindbrain

1996 • 53 citations

Expression of mRNA for follistatin and inhibin/activin subunits during follicular growth and atresia

1994 • 52 citations

Interactions between activin and follicle-stimulating hormone-suppressing protein and their mechanisms of action on cultured rat granulosa cells

1991 • 52 citations

Localization of the heparin binding site of follistatin

1992 • 52 citations

Localization of ovine follistatin and α and βA inhibin mRNA in the sheep ovary during the oestrous cycle

1994 • 52 citations

Immunoradiometric assay for follistatin: serum immunoreactive follistatin levels in normal adults and pregnant women.

1996 • 51 citations

The Rat Follistatin Gene is Highly Expressed in Decidual Tissue

1990 • 51 citations

Activin A and follistatin are dynamically regulated during human pregnancy

1997 • 51 citations

Pituitary activin receptor subtypes and follistatin gene expression in female rats: differential regulation by activin and follistatin.

1996 • 51 citations

Decrease in the expression of a novel TGF β1-inducible and ras-recision gene, TSC-36, in human cancer cells

1997 • 51 citations

A Novel Transmembrane Protein with Epidermal Growth Factor and Follistatin Domains Expressed in the Hypothalamo‐Hypophysial Axis of Xenopus laevis

1996 • 50 citations

Follistatin concentrations in male sheep increase following sham castration/castration or injection of interleukin-1β

1996 • 50 citations

Follistatin and activin in bone: expression and localization during endochondral bone development.

1996 • 50 citations

SPARC, an extracellular matrix glycoprotein containing the follistatin module, is expressed by astrocytes in synaptic enriched regions of the adult brain

1995 • 49 citations

Testing the Agrin Hypothesis

1996 • 48 citations

Production of follistatin in porcine endothelial cells: differential regulation by bacterial compounds and the synthetic glucocorticoid RU 28362.

1996 • 47 citations

Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis

1991 • 47 citations

Increased follistatin (activin-binding protein) gene expression in rat anterior pituitary tissue after ovariectomy may be mediated by pituitary activin.

1993 • 46 citations

The Effect of Follicle-Stimulating Hormone-Suppressing Protein or Follistatin on Luteinizing Bovine Granulosa Cellsin Vitroand its Antagonistic Effect on the Action of Activin*

1991 • 46 citations

SC1, a brain extracellular matrix glycoprotein related to SPARC and follistatin, is expressed by rat cerebellar astrocytes following injury and during development

1996 • 45 citations

Identification of the two types of specific receptor for activin/EDF expressed on friend leukemia and embryonal carcinoma cells

1989 • 45 citations

Characterization of activin A binding sites on the human leukemia cell line K562

1988 • 45 citations

The Heparin Binding Site of Follistatin Is Involved in Its Interaction with Activin

1995 • 44 citations

The decidual prolactin receptor and its regulation by decidua-derived factors.

1996 • 44 citations

A Two-Site Chemiluminescent Assay for Activin-Free Follistatin Reveals That Most Follistatin Circulating in Men and Normal Cycling Women Is in an Activin-Bound State

1998 • 43 citations

Regulation of follistatin messenger ribonucleic acid levels in the rat pituitary.

1993 • 42 citations

Measurement of activin in biological fluids by radioimmunoassay, utilizing dissociating agents to remove the interference of follistatin

1996 • 42 citations

Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development

1992 • 40 citations

Identification of activins and follistatin proteins in human follicular fluid and placenta.

1995 • 40 citations

Differential regulation of inhibin/activin α- and βA-subunit and follistatin mRNAs by cyclic AMP and phorbol ester in cultured human granulosa-luteal cells

1996 • 39 citations

Determination of free follistatin levels in sera of normal subjects and patients with various diseases

1996 • 39 citations

Regulation of steady-state follistatin mRNA levels in rat granulosa cells in vitro

1992 • 39 citations

Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A

1996 • 38 citations

Interaction between activin and follicle-stimulating hormone-suppressing protein/follistatin in the regulation of basal inhibin production by cultured rat granulosa cells.

1992 • 38 citations

In VivoComparison of the Follicle-Stimulating Hormone-Suppressing Activity of Follistatin and Inhibin in Ovariectomized Rats*

1991 • 37 citations

Structural and functional characterization of the rat follistatin (activin-binding protein) gene promoter

1993 • 37 citations

Regulation of the expression of follistatin in rat hepatocytes

1997 • 37 citations

Role of Activin-A and Follistatin in Foam Cell Formation of THP-1 Macrophages

1997 • 36 citations

Expression of follistatin mRNA by somatotropes and mammotropes early in the rat estrous cycle.

1993 • 36 citations

Cell-specific expression of activin and its two binding proteins in the rat decidua: role of alpha 2-macroglobulin and follistatin.

1995 • 35 citations

Ovine anterior pituitary production of follistatin in vitro.

1995 • 35 citations

The effects of follistatin, activin and inhibin on steroidogenesis by bovine thecal cells

1993 • 33 citations

PLASMA FOLLISTATIN CONCENTRATIONS INCREASE FOLLOWING LIPOPOLYSACCHARIDE ADMINISTRATION IN SHEEP

1996 • 33 citations

Norepinephrine reverses the effects of activin A on DNA synthesis and apoptosis in cultured rat hepatocytes

1996 • 33 citations

Differential Control of Activin, Inhibin and Follistatin Proteins in Cultured Rat Granulosa Cells

1993 • 33 citations

Demonstration of Activin-A in Arteriosclerotic Lesions

1994 • 33 citations

Isolation and Characterization of Xenopus Follistatin and Activins

1993 • 32 citations

Radioimmunoassay of FSH-suppressing protein in the ewe concentrations during the oestrous cycle and following ovariectomy

1993 • 32 citations

Effects of bovine 35 kDa FSH-suppressing protein on FSH and LH in rat pituitary cells in vitro: comparison with bovine 31 kDa inhibin

1990 • 32 citations

Inhibin, activin and follistatin bind preferentially to the transformed species of alpha 2-macroglobulin

1997 • 31 citations

Regulation of follistatin messenger ribonucleic acid in cultured rat granulosa cells

1995 • 31 citations

Follistatin decreases activin-stimulated FSH secretion with no effect on GnRH-stimulated FSH secretion in prepubertal male monkeys.

1994 • 31 citations

Isolation, culture, and characterization of the two cell subpopulations forming the rat decidua: differential gene expression for activin, follistatin, and decidual prolactin-related protein.

1995 • 30 citations

Ectopic Expression of SPARC inXenopusEmbryos Interferes with Tissue Morphogenesis: Identification of a Bioactive Sequence in the C-terminal EF Hand

1997 • 29 citations

Activin-binding protein follistatin messenger ribonucleic acid and secreted protein levels are induced by chorionic gonadotropin in cultured human granulosa-luteal cells.

1994 • 29 citations

Follistatins and α<sub>2</sub>-Macroglobulin Are Soluble Binding Proteins for Inhibinand Activin

1996 • 29 citations

Circulating levels of follistatin from puberty to menopause

1996 • 29 citations

Localization of follistatin, an activin-binding protein, in bone tissues

1994 • 28 citations

Endothelial Cell Expression of Testican mRNA

1997 • 28 citations

Gonadotropin-releasing hormone regulation of pituitary follistatin gene expression during the primary follicle-stimulating hormone surge.

1996 • 28 citations

Interleukin-1β Regulates Pituitary Follistatin and Inhibin/Activin βB mRNA Levels and Attenuates FSH Secretion in Response to Activin-A

1998 • 28 citations

Regulation of vascular morphogenesis by the matricellular protein SPARC

1997 • 27 citations

Effects of activin A on deoxyribonucleic acid synthesis, iodine metabolism, and cyclic adenosine monophosphate accumulation in porcine thyroid cells.

1995 • 27 citations

Development and validation of a radioimmunoassay for follistatin in human serum

1994 • 27 citations

Regulation of Follistatin Production by Rat Granulosa Cells in Vitro*

1997 • 26 citations

Site-specific mutagenesis of human follistatin

1991 • 25 citations

Expression of follistatin, an activin-binding protein, in vascular smooth muscle cells and arteriosclerotic lesions.

1993 • 24 citations

Abundant (A)_n·(T)_n mononucleotide repeats in the pig genome: linkage mapping of the porcine APOB, FSA, ALOX12, PEPN and RLN loci

1993 • 24 citations

Regulation of follistatin gene expression in the ovary and in primary cultures of porcine granulosa cells

1994 • 24 citations

Development and characterization of a simian virus 40-transformed, temperature-sensitive rat antimesometrial decidual cell line.

1995 • 24 citations

Depleted level of heparan sulfate proteoglycan in the extracellular matrix of endothelial cell cultures exposed to endotoxin

1994 • 24 citations

Chronic Inhibitory Effect of Follicle-Stimulating Hormone (FSH)-Suppressing Protein (FSP) or Follistatin on Activin- and Gonadotropin-Releasing Hormone-Stimulated FSH Synthesis and Secretion in Cultured Rat Anterior Pituitary Cells*

1990 • 23 citations

Rat follistatin: Ontogeny of steady-state mRNA levels in different tissues predicts organ-specific functions

1991 • 23 citations

Stimulation of progesterone secretion by recombinant follistatin-288 in human granulosa cells.

1993 • 21 citations

Effects of LHRH, FSH and Activin A on Follistatin Secretion from Cultured Rat Anterior Pituitary Cells.

1996 • 20 citations

Follistatin has a biphasic response but follicle-stimulating hormone is unchanged during an inflammatory episode in growing lambs

1998 • 20 citations

Regulation of follicle-stimulating hormone receptor messenger ribonucleic acid levels in cultured rat granulosa cells

1995 • 20 citations

Effects of estrous cycle stage and pregnancy on follistatin gene expression and immunoreactivity in rat reproductive tissues: progesterone is implicated in regulating uterine gene expression.

1993 • 20 citations

Inhibin and follistatin concentrations in fetal tissues and fluids during gestation in sheep: evidence for activin in amniotic fluid

1994 • 20 citations

Distribution of follistatin messenger ribonucleic acid in the rat brain: implications for a role in the regulation of central reproductive functions.

1996 • 19 citations

Ovine follistatin: characterization of cDNA and expression in sheep ovary during the luteal phase of the oestrous cycle

1992 • 19 citations

Follistatin steady state messenger ribonucleic acid levels in confluent cultures of a rat renal mesangial cell line are regulated by multiple factors.

1992 • 19 citations

Characterization of Antisera Directed against Follistatin/Activin-Binding Protein Peptides.

1991 • 18 citations

Characterization of inhibin and related proteins in bovine fetal testicular and ovarian extracts: evidence for the presence of inhibin subunit products and FSH-suppressing protein

1992 • 18 citations

Regulation of follistatin messenger ribonucleic acid in steroidogenic rat granulosa cell lines.

1995 • 17 citations

Rapid Identification of Differentially Expressed Endothelial Cell Genes by RNA Display

1995 • 17 citations

Expression of mRNA for follicle-stimulating hormone suppressing protein in ovarian tissues of cows

1992 • 16 citations

Expression of the genes for α inhibin, βA inhibin and follistatin in the ovaries of Booroola ewes which were homozygotes or non-carriers of the fecundity gene FecB

1992 • 15 citations

Production of activin A and follistatin in cultured rat vascular smooth muscle cells

1995 • 15 citations

Follistatin but not α or βA inhibin subunit mRNA is expressed in ovine fetal ovaries in late gestation

1994 • 15 citations

Human Recombinant Follistatin-288 Suppresses Plasma Concentrations of Follicle-Stimulating Hormone but is not a Significant Regulator of Luteinizing Hormone in Castrated Rams1

1995 • 15 citations

Follistatin-like immunoreactivity in the cytoplasm and nucleus of spermatogenic cells in the rat

1997 • 15 citations

Regulation of follistatin messenger ribonucleic acid in porcine granulosa cells by epidermal growth factor and the protein kinase-C pathway.

1993 • 15 citations

Stimulation of Follistatin Production by Epidermal Growth Factor in Cultured Rat Hepatocytes

1994 • 15 citations

Regulation of the Activin-Binding Protein Follistatin in Cultured Human Luteinizing Granulosa Cells: Characterization of the Effects of Follicle Stimulating Hormone, Prostaglandin E2, and Different Growth Factors1

1995 • 14 citations

Expression of follistatin messenger ribonucleic acid in Sertoli cell-enriched cultures: regulation by epidermal growth factor and protein kinase C-dependent pathway but not by follicle-stimulating hormone and protein kinase A-dependent pathway

1993 • 14 citations

Acute inhibitory effect of follicle-stimulating hormone-suppressing protein (FSP) on gonadotropin-releasing hormone-stimulated gonadotropin secretion in cultured rat anterior pituitary cells

1990 • 14 citations

Regulation of Pulsatile Gonadotropin Secretion by Estrogen, Inhibin, and Follistatin (Activin-Binding Protein) in Ovariectomized Rats 1

1992 • 13 citations

Studies in sheep examining plasma follistatin elevations due to frequent blood sampling or surgery

1996 • 12 citations

Activin inhibits but inhibin activates mouse placental lactogen-II secretion

1995 • 11 citations

The testis is not the major source of circulating follistatin in the ram

1996 • 11 citations

Regulation of human chorionic gonadotropin secretion and messenger ribonucleic acid levels by follistatin in the NUCC-3 choriocarcinoma cell line.

1994 • 10 citations

Mouse Growth Hormone-Releasing Factor Secretion is Activated by Inhibin and Inhibited by Activin in Placenta

1995 • 10 citations

Activin-Attenuated Expression of Transcripts Encoding Granulosa Cell-Derived Insulin-Like Growth Factor Binding Proteins 4 and 5 in the Rat: A Putative Antiatretic Effect1

1997 • 8 citations

Unique Recognition of Activin and Inhibin by Polyclonal Antibodies to Inhibin Subunits

1996 • 6 citations

Alterations of Heparan Sulfate Moieties in Cultured Endothelial Cells Exposed to Endotoxin

1996 • 6 citations

Effects of inhibin on activin A-Induced glucose metabolism in rat hepatocytes

1996 • 5 citations

Attenuation of glycogenolytic action of activin A in intact rat liver

1995 • 4 citations

Changes in the immunoreactivity of follistatin within preovulatory follicles after the primary gonadotrophin surge in rats

1994 • 4 citations

Analysis of tissue organization by microinjection of follistatin into early Xenopus laevis embryos

1995 • 4 citations

Divergent changes in circulating inhibin and follistatin during puberty in girls

1998 • 1 citations

Deleted Work

1955 • 0 citations