Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

Antibodies, a laboratory manual

1989 • 12,929 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Role of integrins and other cell adhesion molecules in tumor progression and metastasis.

1993 • 668 citations

Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion and metastasis

1993 • 606 citations

Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin

1991 • 560 citations

The biology of SPARC, a protein that modulates cell‐matrix interactions

1994 • 533 citations

Role of the alpha v beta 3 integrin in human melanoma cell invasion.

1992 • 414 citations

SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.

1989 • 375 citations

Treatment and Prevention of Rat Glioblastoma by Immunogenic C6 Cells Expressing Antisense Insulin-Like Growth Factor I RNA

1993 • 328 citations

SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway.

1993 • 274 citations

Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.

1993 • 260 citations

Modulation of the Metastatic Activity of Melanoma Cells by Laminin and Fibronectin

1984 • 258 citations

SPARC is a source of copper-binding peptides that stimulate angiogenesis.

1994 • 247 citations

Increased expression of osteonectin and osteopontin, two bone matrix proteins, in human breast cancer.

1995 • 234 citations

Role of laminin receptor in tumor cell migration.

1987 • 227 citations

The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells.

1991 • 223 citations

Distribution of SPARC in normal and neoplastic human tissue.

1995 • 214 citations

Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.

1990 • 178 citations

Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin‐3 and BM‐40/SPARC genes

1995 • 174 citations

Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape.

1990 • 164 citations

The Expression of the Secreted Protein Acidic and Rich in Cysteine (SPARC) Is Associated with the Neoplastic Progression of Human Melanoma

1997 • 160 citations

Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity.

1995 • 152 citations

The 72 kDa type IV collagenase is modulated via differential expression of alpha v beta 3 and alpha 5 beta 1 integrins during human melanoma cell invasion.

1993 • 147 citations

Differential effects of SPARC and cationic SPARC peptides on DNA synthesis by endothelial cells and fibroblasts

1993 • 139 citations

SPARC, an extracellular matrix protein with tumor-suppressing activity in human ovarian epithelial cells.

1996 • 135 citations

Regulation of gene expression by SPARC during angiogenesis in vitro. Changes in fibronectin, thrombospondin-1, and plasminogen activator inhibitor-1.

1992 • 96 citations

Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix

1996 • 80 citations

High‐affinity and low‐affinity calcium binding and stability of the multidomain extracellular 40‐kDa basement membrane glycoprotein (BM‐40/SPARC/osteonectin)

1992 • 79 citations

Antisense approaches to cancer gene therapy.

1995 • 65 citations

Changes in Calcium and Collagen IV Binding Caused by Mutations in the EF Hand and Other Domains of Extracellular Matrix Protein BM-40 (SPARC, Osteonectin)

1994 • 63 citations

Motility of human carcinoma cells in response to thrombospondin: relationship to metastatic potential and thrombospondin structural domains.

1993 • 51 citations

Osteonectin/SPARC Regulates Cellular Secretion Rates of Fibronectin and Laminin Extracellular Matrix Proteins

1994 • 43 citations

Expression of Cathepsin D in Primary and Metastatic Human Melanoma and Dysplastic Nevi

1995 • 41 citations

Latent fibronectin‐degrading serine proteinase activity in N‐terminal heparin‐binding domain of human plasma fibronectin

1991 • 37 citations

Inhibition of tumor growth in liver epithelial cells transfected with a transforming growth factor alpha antisense gene.

1994 • 35 citations

Expression of SPARC is correlated with altered morphologies in transfected F9 embryonal carcinoma cells

1992 • 28 citations

Comparative expression of the SPARC and stromelysin-3 genes in mammary tumours

1996 • 15 citations

Truncated fibronectin. An autologous growth-promoting substance secreted by renal carcinoma cells

1992 • 8 citations