Opposing Effects of Activin A and Follistatin on Developing Skeletal Muscle Cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

1990 • 1,484 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

Wnt-3a regulates somite and tailbud formation in the mouse embryo.

1994 • 784 citations

A molecular pathway determining left-right asymmetry in chick embryogenesis

1995 • 781 citations

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

1985 • 722 citations

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.

1991 • 677 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice

1995 • 634 citations

Multiple defects and perinatal death in mice deficient in follistatin

1995 • 586 citations

Two myogenic lineages within the developing somite

1992 • 570 citations

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

1995 • 504 citations

Regulation of Pax-3 expression in the dermomyotome and its role in muscle development

1994 • 491 citations

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

1994 • 470 citations

Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone.

1987 • 448 citations

PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONS

1973 • 426 citations

Alterations of enzymatic activities during muscle differentiation in vitro

1971 • 415 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

FGF-4 and BMP-2 have opposite effects on limb growth

1993 • 377 citations

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

1989 • 373 citations

Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification

1994 • 372 citations

Myogenic cell lineages

1992 • 360 citations

FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains

1992 • 333 citations

AN ANALYSIS OF MYOGENESIS BY THE USE OF FLUORESCENT ANTIMYOSIN

1957 • 324 citations

Activin Receptors and Cellular Signaling by the Receptor Serine Kinase Family

1994 • 259 citations

Follistatin Binds to both Activin and Inhibin through the Common Beta-Subunit

1991 • 258 citations

Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins

1994 • 252 citations

Transforming growth factor-beta. A very potent inhibitor of myoblast differentiation, identical to the differentiation inhibitor secreted by Buffalo rat liver cells.

1986 • 247 citations

Repression of myogenic differentiation by aFGF, bFGF, and K-FGF is dependent on cellular heparan sulfate.

1992 • 241 citations

How is myogenesis initiated in the embryo?

1996 • 231 citations

Insulin-like Growth Factors (IGF) in Muscle Development

1989 • 228 citations

Fibroblast Growth Factor and Transforming Growth Factor β Repress Transcription of the Myogenic Regulatory Gene MyoD1

1989 • 212 citations

Activation of different myogenic pathways: myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm

1996 • 212 citations

Sequential activation of three myogenic regulatory genes during somite morphogenesis in quail embryos

1992 • 210 citations

Pax3 Inhibits Myogenic Differentiation of Cultured Myoblast Cells

1995 • 209 citations

Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation

1992 • 209 citations

Activin-mediated mesoderm induction requires FGF

1994 • 208 citations

Insulin and IGF-I induce pronounced hypertrophy of skeletal myofibers in tissue culture

1991 • 204 citations

Basic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors.

1989 • 172 citations

Myogenesis in paraxial mesoderm: preferential induction by dorsal neural tube and by cells expressing Wnt-1

1995 • 171 citations

Myogenic Regulatory Factors: Dissecting Their Role and Regulation during Vertebrate Embryogenesis

1993 • 164 citations

Acidic and basic fibroblast growth factors in the nervous system: distribution and differential alteration of levels after injury of central versus peripheral nerve

1991 • 161 citations

Preferential enhancement of myoblast differentiation by insulin‐like growth factors (IGF I and IGF II) in primary cultures of chicken embryonic cells

1983 • 159 citations

Detection and purification of inhibin using antisera generated against synthetic peptide fragments

1989 • 153 citations

Loss of fibroblast growth factor receptors is necessary for terminal differentiation of embryonic limb muscle

1996 • 151 citations

MSX1 inhibits MyoD expression in fibroblast × 10T½ cell hybrids

1995 • 142 citations

Sequential appearance of muscle‐specific proteins in myoblasts as a function of time after cell division: Evidence for a conserved myoblast differentiation program in skeletal muscle

1994 • 139 citations

The tissue distribution of activin beta A- and beta B-subunit and follistatin messenger ribonucleic acids suggests multiple sites of action for the activin-follistatin system during human development.

1994 • 136 citations

Differential response of embryonic and fetal myoblasts to TGFβ: a possible regulatory mechanism of skeletal muscle histogenesis

1994 • 135 citations

Follistatins: More than follicle-stimulating hormone suppressing proteins

1993 • 131 citations

Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo

1993 • 130 citations

Mouse limb muscle is determined in the absence of the earliest myogenic factor myf-5.

1994 • 128 citations

Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain

1994 • 126 citations

Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis

1995 • 118 citations

Activin and Its Receptors during Gastrulation and the Later Phases of Mesoderm Development in the Chick Embryo

1995 • 117 citations

MyoD, myogenin independent differentiation of primordial myoblasts in mouse somites.

1992 • 115 citations

Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1.

1989 • 112 citations

Clonal analysis of vertebrate myogenesis

1988 • 108 citations

The mRNAs encoding acidic FGF, basic FGF and FGF receptor are coordinately downregulated during myogenic differentiation

1991 • 104 citations

Skeletal myogenesis: genetics and embryology to the fore

1993 • 103 citations

Thein VivoExpression of the FGF Receptor FREK mRNA in Avian Myoblasts Suggests a Role in Muscle Growth and Differentiation

1995 • 100 citations

Fibroblast growth factor receptor levels decrease during chick embryogenesis.

1990 • 99 citations

Transforming growth factor beta induces myoblast differentiation in the presence of mitogens.

1992 • 99 citations

FGF-mediated aspects of skeletal muscle growth and differentiation are controlled by a high affinity receptor, FGFR1

1992 • 72 citations

Activin A inhibits Pax-6 expression and perturbs cell differentiation in the developing spinal cord in vitro.

1995 • 64 citations

Inhibins, activins and follistatins

1989 • 54 citations

Follistatin is a developmentally regulated cytokine in neural differentiation.

1992 • 52 citations

Activin A and follistatin expression in developing targets of ciliary ganglion neurons suggests a role in regulating neurotransmitter phenotype

1995 • 48 citations

RADIOIMMUNOASSAY OF FOLLISTATIN: APPLICATION FOR IN VITRO FERTILIZATION PROCEDURES

1990 • 44 citations

Maturation of Myogenic and Chondrogenic Cells in the Presomitic Mesoderm of the Chick Embryo

1994 • 44 citations

Expression pattern of the activin receptor type IIA gene during differentiation of chick neural tissues, muscle and skin

1992 • 37 citations

Sequence of a cDNA clone encoding chicken ribosomal protein S17

1988 • 27 citations