Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent atp-dependent transport across the canalicular membrane

Methods of enzymatic analysis

1966 • 4,073 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1993 • 1,437 citations

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

1992 • 1,362 citations

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

1992 • 903 citations

Drug glucuronidation in humans

1991 • 357 citations

Hereditary Chronic Conjugated Hyperbilirubinemia in Mutant Rats Caused by Defective Hepatic Anion Transport

1985 • 352 citations

The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles

1989 • 329 citations

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators.

1986 • 328 citations

UDP-glucuronosyltransferases

1989 • 327 citations

Peroxisome proliferation and hepatocarcinogenesis

1987 • 310 citations

ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates.

1990 • 299 citations

Expression of the Multidrug-Resistant Gene in Hepatocarcinogenesis and Regenerating Rat Liver

1987 • 274 citations

UDP-glucur-onosyltransferases

1989 • 240 citations

The Effect of Peroxisome Prouferators on Microsomal. Peroxisomal, and Mitochondrial Enzyme Activities in the Liver and Kidney

1987 • 211 citations

Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system.

1991 • 203 citations

ATP-dependent transport of taurocholate across the hepatocyte canalicular membrane mediated by a 110-kDa glycoprotein binding ATP and bile salt.

1991 • 176 citations

Characterization of the ATP‐dependent leukotriene C₄ export carrier in mastocytoma cells

1994 • 157 citations

Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

1987 • 143 citations

Separate transport systems for biliary secretion of sulfated and unsulfated bile acids in the rat.

1988 • 142 citations

ATP/Mg2+-dependent Cardiac Transport System for Glutathione S-Conjugates

1989 • 137 citations

ATP-dependent taurocholate transport by rat liver canalicular membrane vesicles*1, *2

1991 • 136 citations

ATP-dependent S-(2,4-dinitrophenyl)glutathione transport in canalicular plasma membrane vesicles from rat liver

1991 • 132 citations

Differential inhibition by cyclosporins of primary‐active ATP‐dependent transporters in the hepatocyte canalicular membrane

1993 • 128 citations

Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver.

1989 • 123 citations

Glutathione transport by inside-out vesicles from human erythrocytes.

1980 • 112 citations

An overview of peroxisome proliferator-induced hepatocarcinogenesis.

1991 • 106 citations

Inhibition by cyclosporin A of Adenosine triphosphate-dependent transport from the hepatocyte into bile

1993 • 104 citations

Leukotrienes: Biosynthesis, transport, inactivation, and analysis

1992 • 90 citations

Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia.

1992 • 89 citations

ATP‐dependent leukotriene export from mastocytoma cells

1991 • 64 citations

Thyromimetic effect of peroxisomal proliferators in rat liver

1991 • 63 citations

ATP stimulates the uptake of S‐dinitrophenylglutathione by rat liver plasma membrane vesicles

1988 • 57 citations

Glucuronide-Forming Enzymes

1971 • 53 citations

[63] Glutathione transferase isoenzymes from rat liver cytosol

1985 • 52 citations

ATP-Dependent transport for glucuronides in canalicular plasma membrane vesicles

1991 • 48 citations

Disposition of clofibrate in the rat

1980 • 47 citations

Irreversible inhibition of hepatic glutathione S-transferase by ciprofibrate, a peroxisome proliferator

1984 • 47 citations

[17] Glucuronide-forming enzymes

1962 • 45 citations

Dubin-Johnson and Rotor Syndromes: Molecular Basis and Pathogenesis

1993 • 45 citations

Impairment of hepatic glutathione S-transferase activity as a cause of reduced biliary sulfobromophthalein excretion in clofibrate-treated rats

1984 • 43 citations

Peroxisome proliferators, a unique set of drug-metabolizing enzyme inducers: commentary on a symposium.

1992 • 38 citations

The acylation of proteins by xenobiotic amphipathic carboxylic acids in cultured rat hepatocytes

1988 • 37 citations

Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents

1987 • 25 citations

Two Distinct Mechanisms for Bilirubin Glucuronide Transport by Rat Bile Canalicular Membrane Vesicles

1992 • 21 citations

Urinary glucuronide excretion of fenofibric and clofibric acid glucuronides in man. Is it polymorphic?

1991 • 19 citations

The induction of adipose conversion by bezafibrate in 3T3-L1 cells. Synergism with dibutyryl-cAMP

1990 • 12 citations

Peroxisome proliferators as inducers and substrates of UDP‐glucuronosyltransferases

1993 • 10 citations

A Method for Determining Blood Volume of the Rat Using Radioactive Phosphorus.

1951 • 10 citations

Influence of clofibrate on hepatic transport of bilirubin and bromosulfophthalein in rats

1979 • 9 citations

Effect of peroxisome proliferators on glutathione-dependent sulphobromophthalein excretion

1992 • 7 citations

A method for the measurement and characterization of protease activities responsible for extracellular or intracellular degradation of collagen precursors

1984 • 3 citations