Differential induction profile of drug-metabolizing enzymes after treatment with hypolipidaemic agents

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Drug Metabolism and Disposition

2014 • 2,466 citations

LABORATORY INVESTIGATION

1956 • 1,491 citations

A Kinetic Photometric Method for Serum γ-Glutamyl Transpeptidase

1969 • 1,222 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1983 • 890 citations

Isolation of an organ specific protein antigen from cell-surface membrane rat liver

1968 • 883 citations

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

1980 • 854 citations

[3] Fractionation of cell components of animal tissues

1955 • 731 citations

NATURE OF THE HEPATOMEGALIC EFFECT PRODUCED BY ETHYL-CHLOROPHENOXY-ISOBUTYRATE IN THE RAT

1965 • 599 citations

Quantitative determination of cytochrome P-450 in rat liver homogenate

1976 • 362 citations

Assay and properties of digitonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver

1972 • 229 citations

Multiple forms of hepatic cytochrome P-450. Purification, characterisation and comparison of a novel clofibrate-induced isozyme with other major forms of cytochrome P-450

1984 • 210 citations

Novel epoxides formed during the liver cytochrome P-450 oxidation of arachidonic acid

1982 • 147 citations

A rapid NAD+-linked assay for microsomal uridine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme

1975 • 143 citations

Differential induction of cytosolic eposide hydrolase, microsomal epoxide hydrolase, and glutathione S-transferase activities

1983 • 135 citations

Analytical Biochemistry

1984 • 111 citations

Biology of disease. Atherosclerosis as a hyperplastic and/or neoplastic process.

1983 • 108 citations

The biochemistry of preneoplastic liver: a common metabolic pattern in hepatocyte nodules

1984 • 101 citations

Continuous fluorometric assay of epoxide hydrase activity

1979 • 96 citations

Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid

1985 • 84 citations

The effect of hypolipidaemic agents on peroxisomal β-oxidation and mixed-function oxidase activities in primary cultures of rat hepatocytes. Relationship between induction of palmitoyl-CoA oxidation and lauric acid hydroxylation

1984 • 69 citations

Electrophilic reactions of acyl-linked glucuronides. Formation of clofibrate mercapturate in humans.

1982 • 64 citations

Inhibitory effect of nafenopin upon the development of diethylnitrosamine-induced enzyme-altered foci within the rat liver

1984 • 60 citations

Bilirubin mono- and di-glucuronide formation by purified rat liver microsomal bilirubin UDP-glucuronyltransferase

1984 • 50 citations

Species differences in the metabolic conjugation of clofibric acid and clofibrate in laboratory animals and man.

1983 • 48 citations

Assessment of the Mulder and Van Doorn kinetic procedure and rapid centrifugal analysis of UDP-glucuronosyltransferase activities

1984 • 39 citations

Comparative ultrastructural study of rat hepatocytes after treatment with the hypolipidemic agents probucol, clofibrate, and fenofibrate

1980 • 33 citations

Structure-dependent induction of bilirubin glucuronidation and lauric acid 12-hydroxylation by arylcarboxylic acids chemically related to clofibrate

1985 • 32 citations

Effects of aflatoxin B1 on the activity of drug-metabolizing enzymes in rat liver

1981 • 31 citations

MOLECULAR FORMS OF GLUTATHIONE S‐TRANSFERASE AND UDP‐GLUCURONYLTRANSFERASE AS HEPATIC PRENEOPLASTIC MARKER ENZYMESa

1983 • 27 citations

Effects of N-nitrosomorpholine and phenobarbital on UDPglucuronyltransferase in putative preneoplastic foci of rat liver

1985 • 25 citations

Induction of laurate ω-hydroxylase by di (2-ethylhexyl)phthalate in rat liver microsomes

1984 • 25 citations

Effect of hepatocarcinogens on epoxide hydrolase and other xenobiotic metabolizing enzymes

1982 • 23 citations

Peroxisome-associated enzymes and serum lipids in tumour-bearing rats treated with peroxisome-proliferating agents

1984 • 12 citations

Differential regulation of two microsomal epoxide hydrolases in hyperplastic nodules from rat liver

1984 • 9 citations

[Comparative biochemical and ultrastructural study of the hepatic response induced in the rat by 2 hypolipemic agents: clofibrate and itanoxone].

1984 • 1 citations

Deleted Work

1955 • 0 citations