The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

1976 • 1,136 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Carcinogenesis by Hepatic Peroxisome Proliferators: Evaluation of the Risk of Hypolipidemic Drugs and Industrial Plasticizers to Humans

1983 • 890 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Baculovirus Expression Vectors: the Requirements for High Level Expression of Proteins, Including Glycoproteins

1987 • 677 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.

1988 • 357 citations

Transcription regulation of peroxisomal fatty acyl-CoA oxidase and enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in rat liver by peroxisome proliferators.

1986 • 328 citations

Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.

1987 • 317 citations

The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.

1987 • 268 citations

Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator.

1989 • 233 citations

Two -acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene

1991 • 198 citations

Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium*1

1991 • 185 citations

The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid.

1982 • 161 citations

Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes.

1990 • 131 citations

Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver.

1989 • 123 citations

The Rat Clofibrate-InducibleCYP4AGene Subfamily I. Complete Intron and Exon Sequence of theCYP4A1andCYP4A2Genes, Unique Exon Organization, and Identification of a Conserved 19-bp Upstream Element

1989 • 122 citations

Isolation and structural characterization of the rat acyl-CoA oxidase gene.

1987 • 101 citations

Factors influencing peroxisome proliferation in cultured rat hepatocytes

1984 • 99 citations

Structural organization of the gene for rat enoyl-CoA hydratase:3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme.

1987 • 74 citations