Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1996 • 3,041 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Sonic hedgehog mediates the polarizing activity of the ZPA

1993 • 2,313 citations

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

1993 • 2,146 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

WWW-query: An on-line retrieval system for biological sequence banks

1996 • 1,475 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

1994 • 801 citations

A positive feedback loop coordinates growth and patterning in the vertebrate limb

1994 • 702 citations

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

1997 • 658 citations

Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

1997 • 654 citations

Molecular Models for Vertebrate Limb Development

1997 • 592 citations

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of β-catenin

1998 • 429 citations

cdc12p, a Protein Required for Cytokinesis in Fission Yeast, Is a Component of the Cell Division Ring and Interacts with Profilin

1997 • 415 citations

Nonsyndromic Deafness DFNA1 Associated with Mutation of a Human Homolog of the Drosophila Gene diaphanous

1997 • 409 citations

diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene

1994 • 408 citations

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse

1985 • 294 citations

Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.

1996 • 284 citations

A Human Homologue of the Drosophila melanogaster diaphanous Gene Is Disrupted in a Patient with Premature Ovarian Failure: Evidence for Conserved Function in Oogenesis and Implications for Human Sterility

1998 • 251 citations

Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.

1996 • 213 citations

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

1997 • 208 citations

'Formins': proteins deduced from the alternative transcripts of the limb deformity gene

1990 • 201 citations

FH3, A Domain Found in Formins, Targets the Fission Yeast Formin Fus1 to the Projection Tip During Conjugation

1998 • 161 citations

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: The proline glycine and methionine-rich motif

1998 • 157 citations

Profilin is required for posterior patterning of the Drosophila oocyte

1996 • 146 citations

The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity

1997 • 135 citations

cyk-1: a C. elegans FH gene required for a late step in embryonic cytokinesis

1998 • 124 citations

Actin cytoskeleton: Are FH proteins local organizers?

1997 • 114 citations

The WW module competes with the SH3 domain?

1996 • 112 citations

Disruption of formin-encoding transcripts in two mutant limb deformity alleles

1990 • 110 citations

Strike three for GLI3

1997 • 93 citations

Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity

1999 • 80 citations

The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation.

1989 • 78 citations

The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5′ HoxD genes during limb pattern formation

1995 • 72 citations

Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of gf-4 and shh in the limb bud

1995 • 67 citations

The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis.

1992 • 63 citations

Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation

1994 • 58 citations

Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci.

1990 • 58 citations

A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin.

1992 • 47 citations

Limb deformity proteins: role in mesodermal induction of the apical ectodermal ridge

1997 • 45 citations

Limb mutants: what can they tell us about normal limb development?

1997 • 41 citations

Genetic Evidence That Formins Function within the Nucleus

1996 • 39 citations

The Role of a Single Formin Isoform in the Limb and Renal Phenotypes of Limb Deformity

1997 • 39 citations

The mouse mutant limb-deformity (ld).

1982 • 35 citations

Molecular Interaction between Limb Deformity Proteins (Formins) and Src Family Kinases

1996 • 34 citations

The Mouseformin(Fmn) Gene: Genomic Structure, Novel Exons, and Genetic Mapping

1997 • 32 citations

Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus.

1993 • 28 citations

The same genomic region is disrupted in two transgene-induced limb deformity alleles

1992 • 25 citations

Limb deformity proteins during avian neurulation and sense organ development

1995 • 16 citations