Alteration of Norepinephrine Metabolism With Desipramine and Zimelidine in Depressed Patients

- STATISTICAL PACKAGE FOR SOCIAL SCIENCES

2014 • 12,091 citations

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

Regulation of noradrenaline release by presynaptic receptor systems

1977 • 1,482 citations

The Biochemistry of Affective Disorders

1967 • 1,183 citations

Presynaptic regulation of catecholamine release

1974 • 1,145 citations

Norepinephrine in Depressive Reactions

1965 • 1,127 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

Methods for Reliable Longitudinal Observation of Behavior

1963 • 480 citations

Effects of some antidepressant drugs on the depletion of intraneuronal brain catecholamine stores caused by 4,α-dimethyl-meta-tyramine

1969 • 417 citations

Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation

1978 • 396 citations

5-HYDROXYINDOLE COMPOUNDS IN THE CEREBROSPINAL FLUID OF PATIENTS WITH PSYCHIATRIC OR NEUROLOGICAL DISEASES

1966 • 375 citations

Biogenic Amines and Depression

1975 • 361 citations

Catecholamine Metabolism, Depressive Illness, and Drug Response

1972 • 341 citations

Antidepressant Response to Tricyclics and Urinary MHPG in Unipolar Patients

1975 • 269 citations

THE ACTION OF DESMETHYLIMIPRAMINE IN COUNTERACTING SEDATION AND CHOLINERGIC EFFECTS OF RESERPINE-LIKE DRUGS

1964 • 131 citations

The use of new methods to measure: The effect of diet and inducers of microsomal enzyme synthesis on cytochrome P-450 in liver homogenates, and on metabolism of dimethyl nitrosamine

1974 • 130 citations

Presence of free, sulfate and glucuronide conjugated 3-methoxy-4-hydroxyphenylglycol (MHPG) in human brain, cerebrospinal fluid and plasma

1977 • 120 citations

Effect of antidepressant drugs on accumulation and disappearance of monoamines formed in vivo from labelled precursors in mouse brain

1970 • 115 citations

Zimelidine: A therapeutic and pharmacokinetic study in depression

1979 • 115 citations

Mass-fragmentography of nanogram quantities of biogenic amine metabolites in human cerebrospinal fluid and whole rat brain

1975 • 108 citations

HYPERTENSION TREATED WITH RAUWOLFIA SERPENTINA (WHOLE ROOT) AND WITH RESERPINE

1955 • 89 citations

Chronic treatment with desipramine caused a sustained decrease of 3,4-dihydroxyphenylglycol-sulphate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain

1977 • 74 citations

High‐Performance Liquid Chromatographic Assay for Imipramine, Desipramine, and Their 2‐Hydroxylated Metabolites

1979 • 72 citations

Single-Dose Kinetics Predict Steady-State Concentrations of Imipramine and Desipramine

1980 • 66 citations

Effect of Low-Dose Clorgyline on 24-Hour Urinary Monoamine Excretion in Patients With Rapidly Cycling Bipolar Affective Disorder

1982 • 58 citations

Specific norepinephrine and serotonin uptake inhibitors in man: A crossover study with pharmacokinetic, biochemical, neuroendocrine and behavioral parameters

1981 • 47 citations

High Correlation of Norepinephrine and Its Major Metabolite Excretion Rates

1982 • 43 citations

Decrease in brain NE turnover after chronic DMI treatment; no effect with iprindole

1978 • 42 citations

Straight-Phase Ion-Pair Chromatography of Zimelidine and Similar Divalent Amines Part I Bioanalysis

1979 • 41 citations

Controlled cross-over study of a 5-HT uptake inhibiting and an NA uptake inhibiting antidepressant.

1981 • 37 citations

Chronic treatment with some atypical antidepressants increases the brain level of 3-methoxy-4-hydroxyphenylglycol (MHPG) in rats

1981 • 36 citations

Desipramine and some other antidepressant drugs decrease the major norepinephrine metabolite 3,4-dihydroxyphenylglycol-sulphate in the rat brain

1977 • 34 citations

Some current views on brain monoamines.

1962 • 34 citations

Assessment of peripheral adrenergic activity and its interactions with drugs in man

1980 • 29 citations

Phenylethylamine (PEA) and phenylacetic acid (PAA) in the urine of chronic schizophrenic patients and controls.

1980 • 23 citations

Reduction in plasma norepinephrine during fenfluramine treatment

1977 • 20 citations

Zimelidine: A new antidepressant?

1978 • 20 citations

On the enzymatic hydrolysis of the sulfate conjugate of 3-methoxy-4-hydroxyphenylglycol (MHPG)

1980 • 14 citations

The central noradrenergic system and affective response to MAO inhibitors

1979 • 13 citations

Serotonin and noradrenaline uptake inhibitors in the treatment of depression – relationship to 5‐HIAA in spinal fluid

1981 • 10 citations

Crossover study of zimelidine and desipramine in depression: evidence for amine specificity [proceedings].

1981 • 10 citations

Efficacy of desmethylimipramine in endogenomorphically depressed patients.

1980 • 7 citations