Single-Dose Kinetics Predict Steady-State Concentrations of Imipramine and Desipramine

Research Diagnostic Criteria

1978 • 6,988 citations

Relationship between Plasma Level and Therapeutic Effect of Nortriptyline

1971 • 467 citations

Clinical Implications of Imipramine Plasma Levels for Depressive Illness

1977 • 322 citations

Blood Levels of Drug at the Equilibrium State after Multiple Dosing

1965 • 245 citations

Relationship between age and tricyclic antidepressant plasma levels

1977 • 196 citations

Amitriptyline plasma levels and therapeutic response

1976 • 194 citations

Self-inhibiting action of nortriptylin's antidepressive effect at high plasma levels

1976 • 161 citations

CLINICAL CHARACTERISTICS OF IMIPRAMINE-INDUCED ORTHOSTATIC HYPOTENSION

1979 • 155 citations

Plasma levels and antidepressive effect of imipramine

1976 • 126 citations

AMITRIPTYLINE PLASMA-CONCENTRATION AND CLINICAL EFFECT

1978 • 118 citations

Pharmacokinetics of desmethylimipramine and nortriptyline in man after single and multiple oral doses ? A cross-over study

1972 • 112 citations

Pharmacokinetics of nortriptyline in man after single and multiple oral doses: The predictability of steady-state plasma concentrations from single-dose plasma-level data

1972 • 99 citations

Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.

1979 • 92 citations

Quantitative determination of imipramine and desipramine in human blood plasma by direct densitometry of thin-layer chromatograms

1973 • 87 citations

Hydroxylated metabolites of tricyclic antidepressants: preclinical assessment of activity.

1979 • 74 citations

Plasma levels of imipramine and desipramine in man after different routes of administration

1975 • 63 citations

Prediction of individual dosage of nortriptyline

1978 • 52 citations

Prediction of steady‐state imipramine and desmethylimipramine plasma concentrations from single‐dose data

1979 • 50 citations

Original Article

1979 • 36 citations

Comparison of single dose kinetics of imipramine, nortriptyline and antipyrine in man

1976 • 33 citations

Effect of simultaneous treatment with low doses of perphenazine on plasma and urine concentrations of nortriptyline and 10-hydroxynortriptyline

1977 • 29 citations