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Chronic treatment with desipramine caused a sustained decrease of 3,4-dihydroxyphenylglycol-sulphate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain

Data up to Jan 2025

Published1977
Citations74
References28

Total Citations Per Year

Abstract

References (28)

Metabolism of normetanephrine-H3 in rat brain—identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite

1968 • 368 citations

Uptake inhibition of biogenic amines by newer antidepressant drugs: Relevance to the dopamine hypothesis of depression

1977 • 264 citations

Stimulation and destruction of the locus coeruleus: Opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex

1973 • 258 citations

The rate of formation of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in brain as an estimate of the rate of formation of norepinephrine.

1973 • 136 citations

Norepinephrine Metabolism and Drugs Used in the Affective Disorders: A Possible Mechanism of Action

1967 • 130 citations

Norepinephrine Turnover and Metabolism in Rat Brain after Long-Term Administration of Imipramine

1970 • 125 citations

The monoamine oxidase B inhibitor deprenyl potentiates phenylethylamine behaviour in rats without inhibition of catecholamine metabolite formation

1975 • 125 citations

Accumulation and disappearance of catecholamines formed from tyrosine-14C in mouse brain; effect of some psychotropic drugs

1968 • 117 citations

Effect of antidepressant drugs on accumulation and disappearance of monoamines formed in vivo from labelled precursors in mouse brain

1970 • 115 citations

Effect of iprindole on norepinephrine turnover and transport

1974 • 93 citations

ACCUMULATION AND METABOLISM OF NOREPINE‐PHRINE IN RAT HYPOTHALAMUS AFTER EXHAUSTIVE STRESS1

1973 • 91 citations

INCREASE OF NORADRENALINE METABOLISM FOLLOWING ELECTRICAL STIMULATION OF THE LOCUS COERULEUS IN THE RAT1

1973 • 79 citations

Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats

1977 • 78 citations

Changes in Norepinephrine Turnover in Rat Brain During Chronic Administration of Imipramine and Protriptyline: A Possible Explanation for the Delay in Onset of Clinical Antidepressant Effects

1971 • 77 citations

ACCUMULATION AND DISAPPEARANCE OF NORADRENALINE AND ITS MAJOR METABOLITES SYNTHESIZED FROM INTRAVENTRICULARLY INJECTED [3H]DOPAMINE IN THE RAT BRAIN

1974 • 73 citations

GLYCOL SULPHATE ESTER FORMATION FROM [14C]NORADRENALINE IN BRAIN AND THE INFLUENCE OF A COMT INHIBITOR

1971 • 64 citations

Effects of Short- and Long-Term Administration of Tricyclic Antidepressants and Lithium on Norepinephrine Turnover in Brain*

1976 • 49 citations

Identification of free and conjugated 3-methoxy-4-hydroxyphenylglycol (MOPEG) in rat brain by gas chromatography and mass fragmentography

1973 • 37 citations

Desipramine and some other antidepressant drugs decrease the major norepinephrine metabolite 3,4-dihydroxyphenylglycol-sulphate in the rat brain

1977 • 34 citations

A METHOD FOR THE ASSAY OF CONJUGATED 3,4‐DIHYDROXYPHENYLGLYCOL, A MAJOR NORADRENALINE METABOLITE IN THE RAT BRAIN

1976 • 33 citations

363Effects of noradrenaline pump blockers on its uptake by synaptosomes from several brain regions; additional evidence for dopamine terminals in the frontal cortex

1974 • 25 citations

Drug Treatment of Mental Disorders

1976 • 24 citations

Separation of conjugated glycol metabolites of [3H]norepinephrine in the rat brain

1974 • 18 citations

Current Developments in Psychopharmacology, Vol. 5

1980 • 17 citations

ESTIMATION OF NORADRENALINE AND ITS MAJOR METABOLITES SYNTHESIZED FROM [3H]TYROSINE IN THE RAT BRAIN

1976 • 17 citations

The effect of amitriptyline, desipramine and imipramine on the in vivo brain synthesis of 3H-noradrenaline from 3H-l-dopa in the rat

1975 • 16 citations

The influence of desipramine and amitriptyline on the accumulation of [3H]noradrenaline and its two major metabolites formed from [3H]tyrosine in the rat brain

1975 • 14 citations

Differences between the effects of acute and long-term treatment with desmethylimipramine on reserpine-induced release of amines from rat brain

1975 • 13 citations

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Chronic treatment with desipramine caused a sustained decrease of… (1977) – Naunyn-Schmiedeberg s Archives of Pharmacology | Metascience Observatory Explorer