Native LDL Induces Proliferation of Human Vascular Smooth Muscle Cells via Redox-Mediated Activation of ERK 1/2 Mitogen-Activated Protein Kinases
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References (53)
Atherosclerosis — An Inflammatory Disease
1999 • 21,494 citations
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
1994 • 8,631 citations
Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia
1995 • 7,378 citations
Reactive oxygen species in cell signaling
2000 • 2,844 citations
Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.
1998 • 2,003 citations
Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.
1989 • 1,914 citations
Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease
1994 • 1,697 citations
West of Scotland Coronary Prevention Study: identification of high-risk groups and comparison with other cardiovascular intervention trials
1996 • 1,584 citations
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
1993 • 1,313 citations
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
1986 • 1,282 citations
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
1993 • 1,169 citations
Separation of plasma lipoproteins by density-gradient ultracentrifugation
1975 • 1,114 citations
Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.
1993 • 992 citations
Modulation of Protein Kinase Activity and Gene Expression by Reactive Oxygen Species and Their Role in Vascular Physiology and Pathophysiology
2000 • 959 citations
Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation.
1984 • 826 citations
p38 Mitogen-activated Protein Kinase Is a Critical Component of the Redox-sensitive Signaling Pathways Activated by Angiotensin II
1998 • 657 citations
Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells
1999 • 563 citations
Methods of Detection of Vascular Reactive Species
2001 • 547 citations
Native Low-Density Lipoprotein Increases Endothelial Cell Nitric Oxide Synthase Generation of Superoxide Anion
1995 • 479 citations
Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries
2001 • 434 citations
Vascular Smooth Muscle Growth: Autocrine Growth Mechanisms
2001 • 383 citations
Golgi-disturbing agents
1998 • 375 citations
Oxidized Low-Density Lipoprotein Induces Apoptosis of Human Endothelial Cells by Activation of CPP32-Like Proteases
1997 • 373 citations
Estrogens as natural antioxidants of membrane phospholipid peroxidation
1987 • 329 citations
Stimulation of aortic smooth muscle cell mitogenesis by serotonin.
1986 • 327 citations
Tetrahydrobiopterin Regulates Superoxide and Nitric Oxide Generation by Recombinant Endothelial Nitric Oxide Synthase
1997 • 281 citations
Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells
2000 • 201 citations
Redox control of vascular smooth muscle proliferation
1998 • 200 citations
Effects of native and oxidized low density lipoproteins on formation and inactivation of endothelium-derived relaxing factor.
1991 • 190 citations
Dual Role of Reactive Oxygen Species in Vascular Growth
1999 • 152 citations
Induction of Growth-related Metabolism in Human Vascular Smooth Muscle Cells by Low Density Lipoprotein
1989 • 131 citations
Proliferation and extracellular matrix synthesis of smooth muscle cells cultured from human coronary atherosclerotic and restenotic lesions
1994 • 125 citations
Native low density lipoprotein-induced calcium transients trigger VCAM-1 and E-selectin expression in cultured human vascular endothelial cells.
1998 • 112 citations
Tumor Necrosis Factor-α Induces Interleukin-6 Production and Integrin Ligand Expression by Distinct Transduction Pathways
1998 • 111 citations
Inhibitory effect of Chinese green tea on endothelial cell-induced LDL oxidation
2000 • 107 citations
Increased Expression and Activation of Stress-Activated Protein Kinases/c-Jun NH2-Terminal Protein Kinases in Atherosclerotic Lesions Coincide with p53
2000 • 86 citations
Proliferative and cytotoxic effects of mildly oxidized low-density lipoproteins on vascular smooth-muscle cells
1995 • 84 citations
Lipoproteins increase growth of mitogen‐stimulated arterial smooth muscle cells
1985 • 82 citations
Potential Role for Ceramide in Mitogen-activated Protein Kinase Activation and Proliferation of Vascular Smooth Muscle Cells Induced by Oxidized Low Density Lipoprotein
1998 • 80 citations
Thrombin-induced MCP-1 Expression Involves Activation of the p22phox-containing NADPH Oxidase in Human Vascular Smooth Muscle Cells
2001 • 74 citations
Novel cellular activities for low density lipoprotein in vascular smooth muscle cells.
1990 • 66 citations
Hyperexpression and Activation of Extracellular Signal–Regulated Kinases (ERK1/2) in Atherosclerotic Lesions of Cholesterol-Fed Rabbits
2000 • 66 citations
Stimulation of mitogen activated protein kinase by LDL and oxLDL in human U‐937 macrophage‐like cells
1996 • 55 citations
LDL Stimulates Mitogen-Activated Protein Kinase Phosphatase-1 Expression, Independent of LDL Receptors, in Vascular Smooth Muscle Cells
1999 • 37 citations
Low-density lipoprotein elevates intracellular calcium and pH in vascular smooth muscle cells and fibroblasts without mediation of LDL receptor
1990 • 33 citations
Cell-mediated oxidation of low-density lipoprotein: the elusive mechanism(s)
1996 • 27 citations
Native and Oxidized Low–Density Lipoproteins Enhance Superoxide Production from Diabetic Rat Glomeruli
2000 • 26 citations
Members of the low density lipoprotein receptor family control diverse physiological processes
2001 • 21 citations
Assessing the benefits of lipid-lowering therapy
1998 • 18 citations
Co-incubation of native and oxidized low-density lipoproteins: potentiation of relaxation impairment
2000 • 10 citations
Antioxidant Properties of Macrophages Toward Low-Density Lipoprotein
2001 • 9 citations
Low‐density lipoprotein‐induced formation of nitric oxide by cultured vascular smooth muscle cells of the rat
1997 • 7 citations
Members of the low density lipoprotein receptor family control diverse physiological processes
2001 • 1 citations