Antioxidant Properties of Macrophages Toward Low-Density Lipoprotein

Low Density Lipoprotein Oxidation and Its Pathobiological Significance

1997 • 1,642 citations

Detection of activated T lymphocytes in the human atherosclerotic plaque.

1989 • 739 citations

Reactive Nitrogen Intermediates Promote Low Density Lipoprotein Oxidation in Human Atherosclerotic Intima

1997 • 470 citations

Human Atherosclerotic Plaque Contains Both Oxidized Lipids and Relatively Large Amounts of α-Tocopherol and Ascorbate

1995 • 357 citations

Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols

1995 • 315 citations

Systemic Inflammatory Parameters in Patients With Atherosclerosis of the Coronary and Peripheral Arteries

1999 • 312 citations

A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides.

1994 • 282 citations

Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

1998 • 243 citations

Expression of Extracellular SOD and iNOS in Macrophages and Smooth Muscle Cells in Human and Rabbit Atherosclerotic Lesions

1998 • 241 citations

7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque

1997 • 240 citations

Formation of Nitric Oxide–Derived Oxidants by Myeloperoxidase in Monocytes

1999 • 229 citations

Thioredoxin reductase, a redox-active selenoprotein, is secreted by normal and neoplastic cells: presence in human plasma.

2000 • 176 citations

Enzymatic reduction of phospholipid and cholesterol hydroperoxides in artificial bilayers and lipoproteins

1990 • 171 citations

Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions

1993 • 159 citations

Nitric Oxide Regulation of Free Radical– and Enzyme-Mediated Lipid and Lipoprotein Oxidation

2000 • 147 citations

Regulation of inducible nitric oxide synthase messenger RNA expression and nitric oxide production by lipopolysaccharide in vivo: the roles of macrophages, endogenous IFN-gamma, and TNF receptor-1-mediated signaling.

1997 • 131 citations

Inhibitory effect of tea flavonoids on the ability of cells to oxidize low density lipoprotein

1999 • 122 citations

Macrophage Glutathione Content and Glutathione Peroxidase Activity Are Inversely Related to Cell-Mediated Oxidation of LDL

1998 • 121 citations

Is oxidized low‐density lipoprotein present in vivo?

1998 • 114 citations

Macrophage Enrichment with the Isoflavan Glabridin Inhibits NADPH Oxidase-induced Cell-mediated Oxidation of Low Density Lipoprotein

1999 • 109 citations

Coexistence of Oxidized Lipids and α-Tocopherol in All Lipoprotein Density Fractions Isolated From Advanced Human Atherosclerotic Plaques

1999 • 106 citations

Biological fate of amino acid, peptide and protein hydroperoxides

1995 • 88 citations

Greater selective uptake by Hep G2 cells of high-density lipoprotein cholesteryl ester hydroperoxides than of unoxidized cholesteryl esters

1993 • 78 citations

Oxidized lipoproteins and nitric oxide

1996 • 75 citations

7,8 Dihydroneopterin Inhibits Low Density Lipoprotein Oxidation in Vitro. Evidence That This Macrophage Secreted Pteridine is an Anti-Oxidant

1995 • 63 citations

Effects of Hypertension on Aortic Antioxidant Status in Human Abdominal Aneurysmal and Occlusive Disease

1991 • 50 citations

Direct Copper Reduction by Macrophages

1997 • 49 citations

Macrophages Require Both Iron and Copper to Oxidize Low-Density Lipoprotein in Hanks’ Balanced Salt Solution

1995 • 43 citations

Nitric Oxide Inhibits Inducible Nitric Oxide Synthase mRNA Expression in RAW 264.7 Macrophages

2000 • 42 citations

Effects of supplementing with vitamin E on the uptake of low density lipoprotein and the stimulation of cholesteryl ester formation in macrophages

1994 • 41 citations

Lipid hydroperoxides inhibit nitric oxide production in RAW264.7 macrophages

1999 • 39 citations

Cell-mediated oxidation of low-density lipoprotein: the elusive mechanism(s)

1996 • 27 citations

Effect of dietary supplementation of beta-carotene on human monocyte-macrophage-mediated oxidation of low density lipoprotein.

1996 • 26 citations

Antioxidant Activities and Redox Regulation of Interferon-Gamma-Induced Tryptophan Metabolism in Human Monocytes and Macrophages

1999 • 25 citations

Trans‐plasma membrane electron transport induces macrophage‐mediated low‐density lipoprotein oxidation

2001 • 23 citations

Prooxidant and Antioxidant Activities of Macrophages in Metal-Mediated LDL Oxidation

1999 • 20 citations

α-Tocopherol supplementation of macrophages does not influence their ability to oxidize LDL

1998 • 19 citations

Inducible Nitric Oxide Synthase Knockout Mouse Macrophages Disclose Prooxidant Effect of Interferon-γ on Low-Density Lipoprotein Oxidation

2000 • 18 citations

Macrophages Can Decrease the Level of Cholesteryl Ester Hydroperoxides in Low Density Lipoprotein

2000 • 16 citations

Molecular Role of Ascorbate in Enhancement of NO Production in Activated Macrophage-Like Cell Line, J774.1.

1999 • 12 citations