Retardation of metastatic tumor growth after immunization with metastasis‐specific monoclonal antibodies

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Enzyme-linked immunosorbent assay, Elisa. 3. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes.

1972 • 3,187 citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

1978 • 2,726 citations

Reshaping human antibodies for therapy

1988 • 1,555 citations

Replacing the complementarity-determining regions in a human antibody with those from a mouse

1986 • 1,356 citations

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.

1984 • 1,002 citations

Treatment of B-Cell Lymphoma with Monoclonal Anti-Idiotype Antibody

1982 • 1,001 citations

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma.

1985 • 566 citations

Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

1982 • 511 citations

Human anti-idiotype antibodies in cancer patients: Is the modulation of the immune response beneficial for the patient?

1984 • 247 citations

Utilization of monoclonal antibodies in the treatment of leukemia and lymphoma

1982 • 243 citations

Monoclonal antibody therapy of malignant melanoma: in vivo localization in cutaneous metastasis after intravenous administration.

1984 • 203 citations

Diagnosis of and therapy for solid tumors with radiolabeled antibodies and immune fragments.

1984 • 179 citations

Effects of monoclonal antibody immunotherapy on patients with gastrointestinal adenocarcinoma.

1984 • 157 citations

Anti-idiotypic mechanisms involved in suppression of a mouse B cell lymphoma, BCL1.

1987 • 142 citations

Antibody-cell interactions: Fc receptors

1989 • 126 citations

Anti-Idiotypic Antibodies Bear the Internal Image of a Human Tumor Antigen

1986 • 126 citations

Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequences of cell-adhesive molecules.

1989 • 125 citations

Tumor therapy with monoclonal antibodies.

1983 • 113 citations

Antibodies as antigens. The use of mouse monoclonal antibodies to focus human T cells against selected targets.

1988 • 105 citations

Immunotoxins

1985 • 98 citations

Characterization of BSp73, a spontaneous rat tumor and its in vivo selected variants showing different metastasizing capacities.

1983 • 90 citations

Monoclonal antibodies inhibit the adhesion of mouse B 16 melanoma cells in vitro and block lung metastasis in vivo.

1983 • 89 citations

Antigenic differences between metastatic and nonmetastatic BSp73 rat tumor variants characterized by monoclonal antibodies.

1989 • 83 citations

Isolation and cultivation in vitro of macrophages from various sources in the mouse.

1966 • 78 citations

Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies.

1985 • 75 citations

Idiotypic cascades in cancer patients treated with monoclonal antibody CO17-1A.

1989 • 69 citations

The mechanism of synergistic complement‐mediated lysis of rat red cells by monoclonal IgG antibodies

1983 • 69 citations

Specific detection of anti-idiotypic immune responses in cancer patients treated with murine monoclonal antibody

1985 • 66 citations

Effect of anti-B16 melanoma monoclonal antibody on established murine B16 melanoma liver metastases.

1987 • 61 citations

T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.

1987 • 57 citations

Idiotype vaccines against human T cell acute lymphoblastic leukemia. I. Generation and characterization of biologically active monoclonal anti-idiotopes.

1987 • 55 citations

Idiotype vaccines against human T cell leukemia. II. Generation and characterization of a monoclonal idiotype cascade (Ab1, Ab2, and Ab3).

1988 • 44 citations

Antiidiotype antibodies in cancer patients receiving monoclonal antibody to carcinoembryonic antigen.

1988 • 37 citations

Normally occurring inhibitory cells for natural killer cell activity

1982 • 34 citations

Characterization of "regulatory" idiotope-specific T cell clones to a monoclonal anti-idiotypic antibody mimicking a tumor-associated antigen (TAA).

1989 • 32 citations

Towards an idiotype vaccine against mammary tumors. Induction of an immune response to breast cancer‐associated antigens by anti‐idiotypic antibodies

1988 • 25 citations

Human Antibody Induction to the Idiotypic and Anti-Idiotypic Determinants of a Monoclonal Antibody Against a Gastrointestinal Carcinoma Antigen

1985 • 25 citations

ADCC of Cultured Human Melanoma Cells: Analysis with Monoclonal Antibodies to Human Melanoma‐associated Antigens

1981 • 22 citations

Anti-idiotypic antibodies and the induction of specific tumor immunity

1987 • 20 citations

Antibody density on rat red cells determines the rate of activation of the complement component Cl

1985 • 20 citations

Monoclonal antibody : production techniques and applications

1987 • 19 citations

Monoclonal anti‐idiotypic antibody mimicking a tumor‐associated sialoglycoprotein antigen induces humoral immune response against human small‐cell lung carcinoma

1989 • 18 citations

Inhibition of growth and induction of enzyme activities in a clonal human hepatoma cell line (Li‐7A): Comparison of the effects of epidermal growth factor and an anti‐epidermal growth factor receptor antibody

1988 • 18 citations

Altered tumor growth in vivo after immunization of mice with antitumor antibodies.

1984 • 17 citations

Syngeneic monoclonal anti-melanoma antibody that inhibits experimental lung metastasis of B16 melanoma.

1986 • 17 citations

Prospects for monoclonal antibody therapy of leukemia and lymphoma

1986 • 15 citations

Targeted cancer treatment

1989 • 14 citations

Idiotypic intramolecular help. Induction of tumor-specific antibodies by monoclonal anti-idiotypic antibody with the help of Fc-specific T helper clones.

1989 • 14 citations

IgG pair formation on one antigenic molecule is the main mechanism of synergy between antibodies in complement‐mediated lysis

1984 • 14 citations

Natural Killer (NK) Cells in the Rat: «Heterogeneity» as Reflection of the Activation Status

1983 • 14 citations

Natural cytotoxicity in lymphatic metastasis

1984 • 12 citations

Comparison of combinations of interferons with tumor specific and nonspecific monoclonal antibodies as therapy for murine B- and T-cell lymphomas.

1988 • 12 citations

Natural and antibody‐dependent killer cells in the thymus

1982 • 11 citations

Functional mimicry of tumor-associated antigens by antiidiotypic antibodies.

1988 • 11 citations

Natural cytotoxicity in lymphatic metastasis

1984 • 11 citations

Modulation by antiidiotypic monoclonal antibodies of immune lysis mediated by anti-HLA monoclonal antibodies.

1989 • 10 citations

Monoclonal antibody therapy of spontaneous AKR T-cell leukemia.

1986 • 8 citations

Growth inhibition of a B cell leukemia: evidence implicating an anti-idiotype immune response for protective tumor immunity.

1986 • 8 citations

Solid tumor-derived target cell susceptibility to macrophages and natural killer/natural cytotoxic cells in the rat

1983 • 7 citations