Antibody density on rat red cells determines the rate of activation of the complement component Cl

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A nonlinear regression program for small computers

1981 • 563 citations

Complement Fixation on Cell Surfaces by 19 S and 7 S Antibodies

1965 • 336 citations

Purification and radiolabeling of human C1q.

1981 • 295 citations

Effect of Chemical and Enzymatic Radioiodination on in Vitro Human Clq Activities

1973 • 232 citations

Initiation of complement activation

1984 • 160 citations

Monoclonal Antibodies as Tools to Analyze the Serological and Genetic Complexities of Major Transplantation Antigens

1979 • 133 citations

Naturally occurring autoantibodies to exoplasmic and cryptic regions of band 3 protein, the major integral membrane protein of human red blood cells.

1984 • 121 citations

The interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. I. Analysis of the mechanism of binding.

1984 • 115 citations

Univalent antibodies kill tumour cells in vitro and in vivo

1982 • 97 citations

Measurement of the association constants of the complexes formed between intact C1q or pepsin-treated C1q stalks and the unactivated or activated C1r2C1s2 tetramers

1983 • 96 citations

Activation of C1r by Proteolytic Cleavage

1976 • 95 citations

Therapeutic potential of monovalent monoclonal antibodies

1984 • 86 citations

Functional affinity constants of the reaction between 125I-labelled C1q and C1q binders and their use in the measurement of plasma C1q concentrations.

1977 • 71 citations

The mechanism of synergistic complement‐mediated lysis of rat red cells by monoclonal IgG antibodies

1983 • 69 citations

Antibody-independent C1 activation by E. coli.

1984 • 62 citations

The role of immune complexes in the activation of the first component of human complement.

1984 • 48 citations

The relationship between the binding ability and the rate of activation of the complement component C1.

1980 • 41 citations

The binding and activation of the C1r-C1s subunit of the first component of human complement

1982 • 41 citations

The Mechanism of Activation of the First Component of Complement by a Univalent Hapten-IgG Antibody Complex

1977 • 40 citations

Differences in Activation of Human and Guinea Pig Complement by Retroviruses

1978 • 35 citations

Dissociation of C1 and concentration dependence of its activation kinetics

1982 • 28 citations

Lysis of hapten-labeled cells by anti-hapten IgG and complement: effect of cell surface hapten density.

1982 • 25 citations

IgG pair formation on one antigenic molecule is the main mechanism of synergy between antibodies in complement‐mediated lysis

1984 • 14 citations

Activation of the human classical complement pathway by a mouse monoclonal hybrid IgG1-2a monovalent anti-TNP antibody bound to TNP-conjugated cells.

1985 • 12 citations

Measurement of antibody-dependent binding, proteolysis, and turnover of C1s on liposomal antigens localizes the fluidity-dependent step in C1 activation

1983 • 7 citations