Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies.

Towards a network theory of the immune system.

1974 • 3,379 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

Myeloma Proteins as Tumor-Specific Transplantation Antigens

1972 • 325 citations

Implications of the presence of an internal image of the antigen in anti-idiotypic antibodies: Possible application to vaccine production

1981 • 296 citations

Neonatal administration of idiotype or antiidiotype primes for protection against Escherichia coli K13 infection in mice.

1984 • 265 citations

Human anti-idiotype antibodies in cancer patients: Is the modulation of the immune response beneficial for the patient?

1984 • 247 citations

Regulation of the immune response to tumor antigens. II. The nature of immunosuppressor cells in tumor-bearing hosts.

1976 • 239 citations

Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells

1980 • 222 citations

p53 transformation-related protein: Detection by monoclonal antibody in mouse and human cells

1981 • 222 citations

Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the activation of silent clones.

1981 • 190 citations

Immunization of mice against African trypanosomiasis using anti-idiotypic antibodies.

1982 • 188 citations

Transplantable mouse tumor line induced by injection of SV40‐transformed mouse kidney cells

1969 • 173 citations

Monoclonal Idiotope Vaccine Against Streptococcus pneumoniae Infection

1984 • 172 citations

Anti-idiotypic antibodies induce neutralizing antibodies to rabies virus glycoprotein

1983 • 167 citations

Syngeneic monoclonal antiidiotype can induce cellular immunity to reovirus.

1984 • 144 citations

Subcellular Localization of Simian Virus 40 Large Tumor Antigen

1979 • 125 citations

Virus-Induced Intranuclear Antigen in Cells Transformed by Papovavirus SV40.

1964 • 123 citations

Regulation of specific cell-mediated cytotoxic response against SV40-induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice.

1979 • 120 citations

Activation of suppressor T cells by tumour cells and specific antibody

1974 • 117 citations

Immune Response to Hepatitis B Surface Antigen: Enhancement by Prior Injection of Antibodies to the Idiotype

1983 • 114 citations

Idiotypic Regulation in Immune Networks

1981 • 109 citations

Enhancement of the immune response to hepatitis B surface antigen. In vivo administration of antiidiotype induces anti-HBs that expresses a similar idiotype.

1984 • 108 citations

Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining.

1984 • 107 citations

Antigenic relationship of SV40 early proteins to purified large T polypeptide

1979 • 101 citations

Relationship between T-antigen and tumor-specific transplantation antigen in simian virus 40-transformed cells

1979 • 94 citations

Nuclear preparations of SV40-transformed cells contain tumors-pecific transplantation antigen activity

1977 • 93 citations

Sendai virus-specific T-cell clones: induction of cytolytic T cells by an anti-idiotypic antibody directed against a helper T-cell clone.

1984 • 87 citations

Antigen- and receptor-driven regulatory mechanisms. I. Induction of suppressor T cells with anti-idiotypic antibodies.

1979 • 81 citations

Common idiotypic determinant associated with human antibodies to hepatitis B surface antigen.

1983 • 81 citations

Antigenic and Immunogenic Characteristics of Nuclear and Membrane-Associated Simian Virus 40 Tumor Antigen

1980 • 77 citations

PROTECTIVE AND CELLULAR IMMUNE RESPONSES TO IDIOTYPIC DETERMINANTS ON CELLS FROM A SPONTANEOUS LYMPHOMA OF NZB/NZW F1 MICE

1974 • 75 citations

Transplantation Immunity to Simian Virus 40-Transformed Cells in Tumor-Bearing Mice. I. Development of Cellular Immunity to Simian Virus 40 Tumor-Specific Transplantation Antigens During Tumorigenesis by Transplanted Cells2

1973 • 75 citations

Simian virus 40 T-antigen-related cell surface antigen: serological demonstration on simian virus 40-transformed monolayer cells in situ

1980 • 73 citations

Idiotype-specific T cell immunity. I. Generation of effector and suppressor T lymphocytes reactive with myeloma idiotypic determinants.

1980 • 69 citations

Suppression of tumor rejection by autologous anti-idiotypic immunity

1980 • 68 citations

Induction of anti-tobacco mosaic virus antibodies in mice by rabbit antiidiotypic antibodies.

1984 • 65 citations

Induction of immunity to a human tumor marker by in vivo administration of anti-idiotypic antibodies in mice.

1984 • 64 citations

Idiotype-Specific Transplantation Resistance to MOPC-315: Abrogation by Post-Immunization Thymectomy

1978 • 60 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg) IX. Analysis of TrAg in mouse cells synthesizing truncated SV40 large T antigen

1983 • 59 citations

Autoregulation of immune responses via idiotype network interactions

1980 • 58 citations

Immunization with idiotypic immunoglobulin protects against development of B lymphocytic leukemia, but emerging tumor cells can evade antibody attack by modulation.

1983 • 58 citations

Reduced tumor growth after low-dose irradiation or immunization against blastic suppressor T cells.

1981 • 52 citations

Variation in Properties of Plaque Progeny of PARA (Defective Simian Papovavirus 40)-Adenovirus 7

1969 • 51 citations

Domains of simian virus 40 large T-antigen exposed on the cell surface

1982 • 50 citations

Association of SV40 large tumor antigen and cellular proteins on the surface of SV40-transformed mouse cells

1982 • 48 citations

Induction of immune responses with anti-idiotypic antibodies: Implications for the induction of protective immunity

1983 • 47 citations

Antiidiotype modulation of herpes simplex virus infection leading to increased pathogenicity

1984 • 45 citations

Immunotherapy of a murine B cell tumor with antibodies and F(ab')2 fragments against idiotypic determinants of its cell surface IgM.

1983 • 37 citations

Cloned cytotoxic T lymphocytes recognize cells expressing discrete fragments of the SV40 tumor antigen.

1984 • 33 citations

Antigenic structure of simian virus 40 large tumor antigen and association with cellular protein p53 on the surfaces of simian virus 40-infected and -transformed cells

1984 • 29 citations

Treatment of lymphoid tumors with anti-idiotype antibodies

1983 • 29 citations

Characterization of Anti-Hepatitis B Surface Antigen Monoclonal Antibodies

1983 • 28 citations

Temperature-Sensitive Mutants of Simian Virus 40

1978 • 25 citations

T cell subset interactions in the regulation of syngeneic tumor immunity.

1981 • 24 citations

Characteristics of a shared idiotype by two IgM anti-herpes simplex virus monoclonal antibodies that recognize different determinants.

1983 • 23 citations

Adoptive transfer of resistance to growth of an idiotype-secreting hybridoma by T cells from idiotypically suppressed mice.

1983 • 22 citations

Altered tumor growth in vivo after immunization of mice with antitumor antibodies.

1984 • 17 citations

Production and characterization of anti-idiotype reagents for the analysis of viral antigen systems

1983 • 15 citations

Regulation of the immune response to tumor antigens. X. Activation of third-order suppressor T cells that abrogate anti-tumor immune responses.

1984 • 14 citations

Comparative behavior of simian virus 40 T-antigen and of tumor-specific surface and transplantation antigens during partial purification.

1978 • 14 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg). VIII. Retention of SV40 TrAg sites on purified SV40 large T antigen following denaturation with sodium dodecyl sulfate

1982 • 9 citations