Natural cytotoxicity in lymphatic metastasis

Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With <sup>125</sup>I-5-Iodo-2′ -deoxyuridine<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1970 • 990 citations

NK Cells and Other Natural Effector Cells

1982 • 624 citations

Role of NK cells in tumour growth and metastasis in beige mice

1980 • 524 citations

The beige mutation in the mouse selectively impairs natural killer cell function

1979 • 467 citations

Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo.

1981 • 395 citations

Role of Natural Killer Cells in the Destruction of Circulating Tumor Emboli23

1980 • 389 citations

In vivo effect of anti-asialo GM1 antibody on natural killer activity

1981 • 272 citations

Target-effector interaction in the natural killer (NK) cell system. II. The isolation of NK cells and studies on the mechanism of killing.

1978 • 266 citations

beta-Estradiol reduces natural killer cells in mice.

1978 • 216 citations

Generation of natural killer cells: an autonomous function of the bone marrow.

1977 • 196 citations

Natural killer cells kill tumour cells at a given stage of differentiation

1981 • 190 citations

Role of natural killer cells in control of cancer metastasis

1982 • 190 citations

In vivo natural reactivity of mice against tumor cells

1980 • 174 citations

Heterospecific cytotoxic cell activity induced during the first three days of acute lymphocytic choriomeningitis virus infection in mice

1977 • 155 citations

DEOXYRIBONUCLEIC ACID METABOLISM IN VIVO: I. CELL PROLIFERATION AND DEATH AS MEASURED BY INCORPORATION AND ELIMINATION OF IODODEOXYURIDINE.

1964 • 152 citations

Relationship Between Metastatic Potential and Resistance to Natural Killer Cellmediated Cytotoxicity in Three Murine Tumor Systems2, 3

1981 • 142 citations

Studies on the mechanism of NK cell lysis.

1982 • 136 citations

The fate of circulating tumors cells. I. Passage of cells through capillaries.

1961 • 130 citations

Death and Metastatic Distribution of Tumor Cells in Mice Monitored With <sup>125</sup>I-Iododeoxyuridine<xref ref-type="fn" rid="FN2">2</xref>

1969 • 122 citations

Expression of metastatic potential of allogenic and xenogeneic neoplasms in young nude mice.

1981 • 109 citations

Cancer cell traffic from the lungs to the liver: An example of metastatic inefficiency

1980 • 108 citations

Target‐Effector Interaction in the Natural Killer Cell System

1978 • 107 citations

Promotion of Tumor Growth In Vivo by Antimacrophage Agents 2

1976 • 101 citations

Effect of Chemotherapeutic Agents on Natural Cell-Mediated Cytotoxicity in Mice2

1978 • 98 citations

Selective depletion of nk cell activityin vivo and its effect on the growth of NK-sensitive and nk-resistant tumor cell variants

1982 • 91 citations

Biological Stability of 5-lodo-2′-deoxyuridine labelled with Iodine-125 after its Incorporation into the Deoxyribonucleic Acid of the Mouse

1965 • 91 citations

Characterization of BSp73, a spontaneous rat tumor and its in vivo selected variants showing different metastasizing capacities.

1983 • 90 citations

Characterization of cloned cytotoxic lymphocytes with NK-like activity.

1983 • 83 citations

Gross‐virus‐induced lymphoma in the rat. IV. Cytotoxic cells in normal rats

1977 • 82 citations

Studies in the mouse of the pharmacology of 5-iododeoxyuridine, an analogue of thymidine

1960 • 81 citations

Augmentation of mouse natural killer activity and induction of interferon by tumor cells in vivo.

1980 • 76 citations

Natural cell‐mediated cytotoxicity in rats. I. Tissue and strain distribution, and demonstration of a membrane receptor for the Fc portion of IgG

1978 • 72 citations

In vitro NK‐activity and in vivo resistance to leukemia: Studies of beige, beige/nude and wild‐type hosts on C57BL background

1980 • 69 citations

Characterization of a lymphoma cell variant selectively resistant to natural killer cells.

1980 • 62 citations

Differential effects of various pharmacological agents on the cytolytic reaction mechanism of the human natural killer lymphocyte: further resolution of programming for lysis and KCIL into discrete stages.

1982 • 60 citations

Metabolic inhibitors render ‘resistant’ target cells sensitive to natural killer cell‐mediated lysis

1981 • 52 citations

The fate of circulating tumor cells. II. A mechanism of cortisone action in increasing metastases.

1962 • 47 citations

YAC-1 variant clones selected for resistance to natural killer cytotoxic factors are also resistant to natural killer cell-mediated cytotoxicity.

1983 • 44 citations

Normal levels of natural cytotoxic cells against solid tumours in NK-deficient beige mice

1981 • 42 citations

Naturally Arising Tumors of the Inbred WAB/Not Rat Strain. II. Immunogenicily of Transplanted Tumors<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 41 citations

Natural killers to rescue immune surveillance?

1982 • 38 citations

Characterization of natural cytotoxicity in vitro in a spontaneous rat tumor model.

1980 • 33 citations

The effect of target cell differentiation on human natural killer cell activity: a specific defect in target cell binding and early activation events.

1982 • 32 citations

Variation in selectivity of tumor cell cytolysis by murine macrophages, macrophage-like cell lines and NK cells

1982 • 31 citations

Variants from a MLV-induced lymphoma selected for decreased sensitivity to NK lysis.

1981 • 28 citations

Active tumor cell resistance to human natural killer lymphocyte attack.

1981 • 28 citations

Natural Killer Cells Do Not Belong to the Recirculating Lymphocyte Population

1982 • 26 citations

Susceptibility of Tumor Cells in Different Phases of the Mitotic Cycle to the Effect of Immune Lymphocytes

1974 • 25 citations

Differential natural killer cell reactivity against T cell lymphomas by cells from normal or stimulated mice.

1980 • 24 citations

NK cell-target interactions: approaches towards definition of recognition structures

1982 • 21 citations

The specificity of rat natural killer cells and cytotoxic macrophages on solid tumor-derived target cells and selected variants.

1981 • 20 citations

Organ distribution of natural cytotoxicity in the rat.

1978 • 19 citations

The facilitation of tumour growth in the lung by cyclophosphamide in artificial and spontaneous metastases models

1979 • 18 citations

Comparison of three isotope-release assays for spontaneous cytotoxicity of macrophages

1978 • 17 citations

Tumor-Promoting Phorbol Esters Induce Macrophage Differentiation from Bone Marrow Precursors

1982 • 15 citations

Natural Killer (NK) Cells in the Rat: «Heterogeneity» as Reflection of the Activation Status

1983 • 14 citations

NK‐patterned binding expressed by non‐NK mouse leukocytes

1982 • 14 citations

Distinctive Characteristics of Host Tumor Resistance in a Rat Fibrosarcoma Model System

1980 • 13 citations

Reduced spontaneous antitumour resistance of the elderly rat is restored by Corynebacterium parvum

1978 • 11 citations

Sensitivity of cloned high- and low-metastatic murine Lewis lung tumor cells to lysis by cytotoxic autoreactive cells.

1981 • 11 citations

Specific Cytotoxicity In Vitro by T-Cell-Enriched Lymphocyte Subpopulations From Rats Bearing Chemically Induced But Not Spontaneous Tumors2

1980 • 11 citations

Augmentation of cell‐mediated cytotoxicity to a rat lymphoma. II. Characterization of the non‐T cytotoxic cells stimulated in vivo by tumour cells as natural killer cells

1979 • 10 citations

Variance in resistance to natural and antibody‐dependent cellular cytotoxicity and to complement‐mediated lysis among K562 lines

1983 • 8 citations

Murine Lymph Node Natural Killer Cells: Regulatory Mechanisms of Activation or Suppression<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1982 • 8 citations

Solid tumor-derived target cell susceptibility to macrophages and natural killer/natural cytotoxic cells in the rat

1983 • 7 citations

Rat Natural Killer (NK) Cells are not Bone Marrow Dependent

1983 • 7 citations

PERMANENTLY GROWING MURINE CELL CLONES WITH NK LIKE ACTIVITIES

1982 • 7 citations