Mechanisms by which cells of the osteoblast lineage control osteoclast formation and activity

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6

1992 • 1,437 citations

Modulation of Osteoclast Differentiation

1992 • 1,014 citations

OSTEOBLASTIC CELLS ARE INVOLVED IN OSTEOCLAST FORMATION

1988 • 943 citations

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

1993 • 827 citations

Osteoclast-Like Cell Formation and its Regulation by Osteotropic Hormones in Mouse Bone Marrow Cultures*

1988 • 745 citations

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.

1994 • 738 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.

1993 • 565 citations

Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption.

1987 • 539 citations

The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells

1989 • 501 citations

Cytokines and Estrogen in Bone: Anti-Osteoporotic Effects

1993 • 466 citations

MACROPHAGE COLONY STIMULATING FACTOR RESTORESIN VIVOBONE RESORPTION IN THEOP/OPOSTEOPETROTIC MOUSE

1990 • 441 citations

Bisphosphonates act on rat bone resorption through the mediation of osteoblasts.

1993 • 422 citations

Interleukin-11: a new cytokine critical for osteoclast development.

1994 • 408 citations

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.

1986 • 392 citations

In vitro formation of osteoclasts from long-term cultures of bone marrow mononuclear phagocytes.

1982 • 333 citations

Osteoblast-Like Cells in the Presence of Parathyroid Hormone Release Soluble Factor that Stimulates Osteoclastic Bone Resorption*

1986 • 317 citations

Tissue specificity and developmental expression of rat osteopontin

1987 • 317 citations

The pathobiology of the osteoclast.

1985 • 280 citations

In vitro osteoclast generation from different bone marrow fractions, including a highly enriched haematopoietic stem cell population

1986 • 273 citations

Molecular endocrinology

1978 • 258 citations

Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro

1991 • 239 citations

Identification of Committed Mononuclear Precursors for Osteoclast-Like Cells Formed in Long Term Human Marrow Cultures*

1990 • 232 citations

Bone cells predispose bone surfaces to resorption by exposure of mineral to osteoclastic contact

1985 • 229 citations

Generation of osteoclasts from isolated hematopoietic progenitor cells

1989 • 201 citations

The Cellular Basis of Bone Resorption

1980 • 201 citations

Gene expression during osteogenic differentiation in mandibular condyles in vitro.

1990 • 177 citations

Role of colony-stimulating factors in osteoclast development

1991 • 176 citations

Induction of Calcitonin Receptors by lα, 25- Dihydroxyvitamin D₃in Osteoclast-Like Multinucleated Cells Formed from Mouse Bone Marrow Cells*

1988 • 169 citations

Modulation of osteoclast differentiation [published erratum appears in Endocr Rev 1992 May;13(2):191]

1992 • 152 citations

Generation of osteoclast-inductive and osteoclastogenic cell lines from the H-2KbtsA58 transgenic mouse.

1993 • 148 citations

Osteoblasts display receptors for and responses to leukemia‐inhibitory factor

1990 • 134 citations

Biphasic Effects of Transforming Growth Factor-β on the Production of Osteoclast-Like Cells in Mouse Bone Marrow Cultures: The Role of Prostaglandins in the Generation of These Cells

1990 • 130 citations

Detection of transcripts for the receptor for macrophage colony-stimulating factor, c-fms, in murine osteoclasts.

1992 • 128 citations

Generation of Osteoclastic Function in Mouse Bone Marrow Cultures: Multinuclearity and Tartrate- Resistant Acid Phosphatase Are Unreliable Markers for Osteoclastic Differentiation*

1989 • 124 citations

The Onset and Progression of Osteoblast Differentiation is Functionally Related to Cellular Proliferation

1989 • 106 citations

Human macrophage colony‐stimulating factor inhibits bone resorption by osteoclasts disaggregated from rat bone

1988 • 101 citations

Colony-stimulating factors regulate the development of multinucleated osteoclasts from recently replicated cells in vitro.

1987 • 95 citations

5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices

1993 • 95 citations

Cloning of an osteoblastic cell line involved in the formation of osteoclast‐like cells

1990 • 88 citations

Experimental study of changes in osteoblastic shape induced by calcitonin and parathyroid extract in an organ culture system

1976 • 85 citations

Structural requirements for the action of parathyroid hormone-related protein (PTHrP) on bone resorption by isolated osteoclasts

1991 • 79 citations

Long‐term culture of disaggregated rat osteoclasts: Inhibition of bone resorption and reduction of osteoclast‐like cell number by calcitonin and PTHrP[107‐139]

1993 • 66 citations

Transforming growth factor beta inhibits plasminogen activator (PA) activity and stimulates production of urokinase‐type PA, PA inhibitor‐1 mRNA, and protein in rat osteoblast‐like cells

1991 • 64 citations

Osteoclast formation from cloned pluripotent hemopoietic stem cells

1989 • 60 citations

The plasminogen activator and inhibitor system in bone remodelling.

1993 • 47 citations

Isolation of a murine osteoclast colony-stimulating factor.

1991 • 45 citations

Plasminogen activator regulation in osteoblasts: Parathyroid hormone inhibition of type‐1 plasminogen activator inhibitor and its mRNA

1992 • 36 citations

Biology of the Osteoclast

1993 • 35 citations

Identification and characterization of osteoclast progenitors by clonal analysis of hematopoietic cells

1992 • 34 citations

Identification of plasminogen activator in osteoclasts

1990 • 30 citations

Constitutive expression of osteoclast-stimulating activity by normal clonal osteoblast-like cells: effects of parathyroid hormone and 1,25-dihydroxyvitamin D3.

1992 • 26 citations

Proliferation of Tartrate-Resistant Acid Phosphatase Positive Multinucleate Cells in Ovariectomized Animals

1990 • 25 citations

Osteoblasts: Differentiation and Function

1993 • 24 citations

Constitutive expression of osteoclast-stimulating activity by normal clonal osteoblast-like cells: effects of parathyroid hormone and 1,25- dihydroxyvitamin D3

1992 • 11 citations

Hormonal Factors Which Regulate Bone Resorption

1993 • 8 citations

Generation of cell lines with potent ability to induce osteoclastic differentiation and stimulate osteoclastic function

1992 • 1 citations