5′ Structural motifs and Xenopus β globin gene activation

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin

1982 • 448 citations

The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence

1979 • 445 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Chromatin assembly in Xenopus oocytes: In vivo studies

1984 • 404 citations

Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

1980 • 378 citations

Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA

1980 • 372 citations

Temporal order of chromatin structural changes associated with activation of the major chicken vitellogenin gene

1983 • 366 citations

DNA methylation, biochemistry, and biological significance

1984 • 343 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

A dominant role for DNA secondary structure in forming hypersensitive structures in chromatin

1983 • 273 citations

Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult β-globin gene: Nature of the binding domain

1985 • 255 citations

A nucleosome-free region in SV40 minichromosomes

1980 • 254 citations

SELECTED TOPICS IN CHROMATIN STRUCTURE

1985 • 253 citations

Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

1984 • 217 citations

Upstream elements necessary for optimal function of the hsp 70 promoter in transformed flies

1984 • 213 citations

A 3′ enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult β-globin gene

1986 • 192 citations

Linkage of adult α- and β-globin genes in X. laevis and gene duplication by tetraploidization

1980 • 188 citations

Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene

1985 • 186 citations

S1-hypersensitive sites in eukaryotic promoter regions

1984 • 168 citations

The human β-globin gene contains a downstream developmental specific enhancer

1987 • 167 citations

Torsional stress promotes the DNAase I sensitivity of active genes

1984 • 145 citations

A complex of interacting DNAase I-hypersensitive sites near the drosophila glue protein gene, Sgs4

1982 • 126 citations

A sequence conserved in both the chicken and mouse alpha 2(I) collagen promoter contains sites sensitive to S1 nuclease.

1984 • 118 citations

(A-T)_ntracts embedded in random sequence DNA — formation of a structure which is chemically reactive and torsionally deformable

1986 • 113 citations

Temperature-sensitive changes in the structure of globin chromatin in lines of red cell precursors transformed by ts-AEV

1982 • 110 citations

The positive transcription factor of the 5S RNA gene induces a 5S DNA-specific gyration in xenopus oocyte extracts

1985 • 98 citations

Differential expression of the members of the discoidin I multigene family during growth and development of Dictyostelium discoideum

1982 • 89 citations

Internal organization of the major adult α- and β-globin genes of X. laevis

1980 • 76 citations

Developmental changes in keratin patterns during epidermal maturation

1985 • 75 citations

Analysis of Xenopus laevis globins during development and erythroid cell maturation and the construction of recombinant plasmids containing sequences derived from adult globin mRNA

1979 • 52 citations

A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.

1984 • 52 citations

A hypersensitive site in hsp70 chromatin requires adjacent not internal DNA sequence

1985 • 52 citations

Perturbation of chromatin structure in the region of the adult beta-globin gene in chicken erythrocyte chromatin

1987 • 49 citations

Chromatin structure, DNA structure

1982 • 44 citations

The complete nucleotide sequence of the major adult beta globin gene of Xenopus laevis.

1983 • 43 citations

Gamma rays and bleomycin nick DNA and reverse the DNase I sensitivity of beta-globin gene chromatin in vivo.

1987 • 43 citations

Simian virus 40-mediated cis induction of the Xenopus β-globin DNase I hypersensitive site

1985 • 42 citations

(AT)n is an interspersed repeat in the Xenopus genome.

1985 • 41 citations

Supercoil-dependent features of DNA structure at Drosophila locus 67B1

1984 • 38 citations

DNase I hypersensitivity and methylation of the 5'-flanking region of the α₁-fetoprotein gene during developmental and glucocorticoid-induced repression of its activity in rat liver

1986 • 36 citations

Modular structure of the beta-globin and the TK promoters.

1984 • 31 citations

Transcriptionally active chromatin is sensitive to Neurospora crassa and S1 nucleases

1984 • 30 citations

DNase I and nuclease S1 sensitivity of the rabbit β1 globin gene in nuclei and in supercoiled plasmids

1985 • 28 citations

Differential expression of the Xenopus laevis tadpole and adult beta-globin genes when injected into fertilized Xenopus laevis eggs.

1984 • 28 citations

Multiple sequence-specific DNA binding activities are eluted from chicken nuclei at low ionic strengths

1985 • 28 citations

Sequential alterations in globin gene chromatin structure during erythroleukemia cell differentiation.

1985 • 25 citations

Fine analysis of the active H5 gene chromatin of chicken erythroid cells at different stages of differentiation

1986 • 25 citations

Demonstration of an S1-nuclease sensitive site near the human β-globin gene, and its protection by HMG 1 and 2

1983 • 23 citations

Quantitation of DNase I sensitivity in Xenopus chromatin containing active and inactive globin, albumin and vitellogenin genes

1981 • 22 citations

RecBC,sbcB independent, (AT)ⁿ- mediated deletion of sequences flanking aXenopus laevis βglobin gene on propagation inE. coli

1986 • 18 citations

A comparison of the promoter strengths of two eukaryotic genesin vitroreveals a region of DNA that can influence the rate of transcription in cis over long distances

1983 • 8 citations