Torsional stress promotes the DNAase I sensitivity of active genes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

DNA Topoisomerases

1981 • 977 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Active chromatin

1982 • 549 citations

Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I

1980 • 486 citations

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

1983 • 458 citations

The regulation of lipomodulin, a phospholipase inhibitory protein, in rabbit neutrophils by phosphorylation.

1981 • 424 citations

Chromatin assembly in Xenopus oocytes: In vivo studies

1984 • 404 citations

Torsional tension in the DNA double helix measured with trimethylpsoralen in living E. coli cells: Analogous measurements in insect and human cells

1980 • 394 citations

The HMG chromosomal proteins

1982 • 385 citations

Interaction of HMG 14 and 17 with actively transcribed genes

1980 • 355 citations

Isolation of a subclass of nuclear proteins responsible for conferring a DNase I-sensitive structure on globin chromatin.

1979 • 337 citations

The interaction of high mobility proteins HMG14 and 17 with nucleosomes

1980 • 232 citations

Chromatin assembly in Xenopus oocytes: In vitro studies

1984 • 230 citations

Transcription of DNA injected into Xenopus oocytes is influenced by template topology

1983 • 219 citations

Nucleosome Cores Have Two Specific Binding Sites for Nonhistone Chromosomal Proteins HMG 14 and HMG 17

1980 • 184 citations

Definition of 5‘ and 3‘ structural boundaries of the chromatin domain containing the ovalbumin multigene family.

1982 • 172 citations

Elastic torsional strain in DNA within a fraction of SV40 minichromosomes: relation to transcriptionally active chromatin.

1982 • 134 citations

Dependence of mammalian DNA replication on DNA supercoiling II. Effects of novobiocin on DNA synthesis in Chinese hamster ovary cells

1979 • 114 citations

Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells

1979 • 112 citations

Properties of active nucleosomes as revealed by HMG 14 and 17 chromatography

1982 • 109 citations

Dependence of mammalian DNA synthesis on DNA supercoiling. III Characterization of the inhibition of replicative and repair-type DNA synthesis by novobiocin and nalidixic acid

1981 • 96 citations

Chromatin structure of the chicken beta-globin gene region. Sensitivity to DNase I, micrococcal nuclease, and DNase II.

1982 • 92 citations

Reconstitution of a deoxyribonuclease I-sensitive structure on active genes.

1980 • 80 citations

Sites Required for Position-Effect Regulation of Mating-type Information in Yeast

1983 • 64 citations

Investigations of the possible functions for glycosylation in the high mobility group proteins. Evidence for a role in nuclear matrix association.

1983 • 61 citations

Affinity of HMG17 for a mononucleosome is not influenced by the presence of ubiquitin-H2A semihistone but strongly depends on DNA fragment size

1983 • 61 citations

Hemoglobin switching in chickens. Is the switch initiated post-transcriptionally?

1982 • 58 citations

The nuclease sensitivity of active genes

1983 • 57 citations

Nonhistone nuclear high mobility group proteins 14 and 17 stabilize nucleosome core particles.

1983 • 52 citations

Molecular biology: Eukaryotic genes—are they under torsional stress?

1983 • 51 citations

The chicken beta globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats.

1982 • 51 citations

Changes in cellular ATP, ADP and AMP levels following treatments affecting cellular respiration and the activity of certain nuclear genes in Drosophila salivary glands

1974 • 51 citations

High mobility group proteins: abundance, turnover and relationship to transcriptionally active chromatin

1983 • 50 citations

Genetics: DNA supercoiling and gene expression

1984 • 45 citations

The high mobility group proteins, HMG 14 and 17, do not prevent the formation of chromatin higher order structure

1982 • 41 citations

Multiple structural features are responsible for the nuclease sensitivity of the active ovalbumin gene.

1981 • 39 citations

Isolation and characterization of the complete chicken β-globin gene region: frequent deletion of the adult β-globin genes in λ

1981 • 38 citations

ts A1S9 locus in mouse L cells may encode a novobiocin binding protein that is required for DNA topoisomerase II activity.

1983 • 38 citations

Enrichment of acetylated histones in polynucleosomes containing high mobility group protein 17 revealed by immunoaffinity chromatography.

1984 • 31 citations

HMG 14/17 binding affinities and DNAase I sensitivities of nucleoprotein particles

1983 • 30 citations

19 DNA Gyrase and Other Type II Topoisomerases

1981 • 28 citations

Studies on the structure of isolated chromatin in three different solvents

1979 • 27 citations

Deoxyribonuclease I generates single-stranded gaps in chromatin deoxyribonucleic acid

1980 • 20 citations

Chromosomal puff induction in salivary glands from Drosophila hydei by arsenite

1977 • 19 citations