S1-hypersensitive sites in eukaryotic promoter regions

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences

1983 • 474 citations

An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin

1982 • 448 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions

1982 • 439 citations

Flipping of cloned d(pCpG)n.d(pCpG)n DNA sequences from right- to left-handed helical structure by salt, Co(III), or negative supercoiling.

1982 • 321 citations

A dominant role for DNA secondary structure in forming hypersensitive structures in chromatin

1983 • 273 citations

Initiation of SV40 DNA replication in vivo: Location and structure of 5′ ends of DNA synthesized in the ori region

1982 • 257 citations

Specific factor conferring nuclease hypersensitivity at the 5' end of the chicken adult beta-globin gene.

1984 • 249 citations

Homocopolymer sequences in the spacer of a sea urchin histone gene repeat are sensitive to S1 nuclease

1982 • 220 citations

Conformation of promoter DNA: Fine mapping of S1-hypersensitive sites

1983 • 216 citations

DNA conformation at the 5′ end of the chicken adult β-globin gene

1983 • 206 citations

DNA Structure and Gene Regulation

1980 • 200 citations

Association of an S1 nuclease-sensitive structure with short direct repeats 5′ of Drosophila heat shock genes

1983 • 171 citations

DNA supercoiling: Another level for regulating gene expression

1981 • 166 citations

Molecular biology: Anatomy of hypersensitive sites

1984 • 119 citations

S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.

1984 • 119 citations

A sequence conserved in both the chicken and mouse alpha 2(I) collagen promoter contains sites sensitive to S1 nuclease.

1984 • 118 citations

T antigen binding and the control of SV40 gene expression

1981 • 108 citations

Multiple origins of transcription in the 4.5 Kb upstream of the ϵ-globin gene

1983 • 98 citations

Mutational dissection of the 21 bp repeat region of the SV40 early promoter reveals that it contains overlapping elements of the early-early and late-early promoters

1984 • 88 citations

Escherichia coli single-strand binding protein stabilizes specific denatured sites in superhelical DNA

1983 • 67 citations

S1 sensitive sites in adenovirus DNA

1983 • 56 citations

Endonuclease S1-sensitive site in chicken pro-alpha 2(I) collagen 5' flanking gene region.

1984 • 49 citations

Mouse primase initiation sites in the origin region of simian virus 40.

1984 • 48 citations

Superhetieity induces hypersensitivity of a human polypyrimldine polypurine DNA sequence in the human α2-α1 globin intergenic region to SI nudease digestion - high resolution mapping of the clustered cleavage sites

1983 • 47 citations

A chicken repetitive DNA sequence that is highly sensitive to single-strand specific endonucleases

1983 • 42 citations