(AT)n is an interspersed repeat in the Xenopus genome.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Selfish DNA: the ultimate parasite

1980 • 2,095 citations

Molecular structure of a left-handed double helical DNA fragment at atomic resolution

1979 • 2,057 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Selfish genes, the phenotype paradigm and genome evolution

1980 • 1,779 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Simple sequences are ubiquitous repetitive components of eukaryotic genomes

1984 • 1,389 citations

The nucleotide sequence of the rat cytoplasmic β–actin gene

1983 • 1,059 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes.

1982 • 759 citations

[9] Gel electrophoresis of restriction fragments

1979 • 653 citations

Transposable elements

1980 • 600 citations

Repetitive Sequences in Eukaryotic DNA and their Expression

1982 • 575 citations

Regulation of Gene Expression: Possible Role of Repetitive Sequences

1979 • 575 citations

Cruciform structures in supercoiled DNA

1981 • 545 citations

The inverted repeat as a recognizable structural feature in supercoiled DNA molecules.

1980 • 519 citations

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1983 • 504 citations

Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences

1983 • 474 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions

1982 • 439 citations

MOLECULAR ARRANGEMENT AND EVOLUTION OF HETEROCHROMATIC DNA

1980 • 412 citations

General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus

1973 • 389 citations

Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

1980 • 378 citations

Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes

1984 • 354 citations

A history of the human fetal globin gene duplication

1981 • 349 citations

Facile transition of poly[d(TG)·d(CA)] into a left-handed helix in physiological conditions

1983 • 335 citations

Antibody diversity: Somatic hypermutation of rearranged VH genes

1981 • 334 citations

The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene

1982 • 323 citations

The sequence (dC-dA)n X (dG-dT)n forms left-handed Z-DNA in negatively supercoiled plasmids.

1983 • 314 citations

Nucleosomes will not form on double-stranded RNA or over poly(dA)-poly(dT) tracts in recombinant DNA

1981 • 244 citations

A member of a new repeated sequence family which is conserved throughout eucaryotic evolution is found between the human δ and β globin genes

1981 • 242 citations

The DNA sequence of sea urchin (S. purpuratus) H2A, H2B and H3 histone coding and spacer regions

1978 • 240 citations

The structure of the vimentin gene

1983 • 227 citations

Chromatin and core particles formed from the inner histones and synthetic polydeoxyribonucleotides of defined sequence

1979 • 208 citations

Conversion of RNA to DNA in mammals: Alu-like elements and pseudogenes

1983 • 202 citations

Mechanisms of divergence and convergence of the human immunoglobulin α1 and α2 constant region gene sequences

1984 • 195 citations

Pseudogenes for human small nuclear RNA U3 appear to arise by integration of self-primed reverse transcripts of the RNA into new chromosomal sites

1983 • 178 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

Molecular structure and evolutionary origin of human cardiac muscle actin gene.

1982 • 155 citations

Comparison of the genes coding for the common 5′ terminal sequence of messenger RNAs in three trypanosome species

1984 • 150 citations

Similarity of the nucleotide sequences of rat α-lactalbumin and chicken lysozyme genes

1984 • 150 citations

Nucleosome reconstitution on plasmid-inserted poly(dA) . poly(dT).

1982 • 139 citations

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

1980 • 138 citations

The conserved nucleotide sequences of Bkm, which define Sxr in the mouse, are transcribed

1984 • 135 citations

Organization of the human myoglobin gene.

1984 • 129 citations

Structural analysis of templates and RNA polymerase III transcripts of Alu family sequences interspersed among the human β-like globin genes

1981 • 128 citations

Non-Alu family interspersed repeats in human DNA and their transcriptional activity

1984 • 128 citations

Transition from noncooperative to cooperative and selective binding of histone H1 to DNA

1976 • 126 citations

Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA.

1982 • 111 citations

Effect of the B--Z transition in poly(dG-m5dC) . poly(dG-m5dC) on nucleosome formation.

1982 • 110 citations

Unusual sequences in the murine immunoglobulin μ–δ heavy-chain region

1983 • 108 citations

The xenopus laevis globin gene family: chromosomal arrangement and gene structure

1983 • 104 citations

The 5′-limit of transposition and upstream barren region of a trypanosome VSG gene: tandem 76 base-pair repeats flanking (TAA)₉₀

1984 • 104 citations

Wrinkled DNA

1983 • 103 citations

Molecular biology: CACA sequences — the ends and the means?

1983 • 88 citations

Internal organization of the major adult α- and β-globin genes of X. laevis

1980 • 76 citations

Mouse rDNA nontranscribed spacer sequences are found flanking immunoglobulin CH genes and elsewhere throughout the genome

1980 • 71 citations

An unusual transposon encoding heat shock inducible and developmentally regulated transcripts in Dictyostelium

1983 • 70 citations

Duplication/deletion polymorphism 5′- to the human β globin gene

1981 • 55 citations

Simple DNA sequences of Drosophila virilis isolated by screening with RNA

1984 • 53 citations

Nucleotide sequences of H1 histone genes fromXenopus laevis. A recently diverged pair of H1 genes and an unusual H1 pseudogene

1983 • 53 citations

A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.

1984 • 52 citations

Assembly of the mitochondrial membrane system. Sequences of yeast mitochondrial tRNA genes.

1980 • 51 citations

Transcriptionin vivoof an Alu family member upstream from the human ε-globin gene

1984 • 50 citations

Synthesis in vitro of an exceptionally long RNA transcript promoted by an AluI sequence

1982 • 50 citations

The control of globin and other eukaryotic genes

1982 • 49 citations

Repeat sequence of a hermit crab satellite deoxyribonucleic acid is (-T-A-G-G-)_n.(-A-T-C-C-)_n

1974 • 48 citations

Replication and expression of Xenopus laevis globin genes injected into fertilized Xenopus eggs.

1983 • 44 citations

Isolation and characterization of recombinant clones containing the chicken adult beta-globin gene.

1979 • 43 citations

The complete nucleotide sequence of the major adult beta globin gene of Xenopus laevis.

1983 • 43 citations

Repetitive satellite-like sequences are present within or upstream from 3 avian protein-coding genes

1983 • 36 citations

Organization and expression of cloned histone gene clusters fromXenopus laevisandX. boreolis

1982 • 36 citations

Selective in vitro transcription of one of the two Alu family repeats present in the 5′ flanking region of the human ε-globin gene

1981 • 31 citations

Conformations of poly[d(A-T-T)]·poly[d(A-A-T)]

1975 • 29 citations

Structure of a pleiomeric form of poly d(AT):poly d(AT)

1984 • 29 citations

Unusual class of Alu sequences containing a potential Z-DNA segment.

1983 • 29 citations

Two nuclear DNA binding proteins ofDictyostelium discoideumwith a high affinity for poly(dA)-poly(dT)

1983 • 28 citations

The organization of the tadpole and adult α globin genes ofXenopus laevis

1982 • 27 citations

Fidelity of transcription of Xenopus laevis globin genes injected into Xenopus laevis oocytes and unfertilized eggs.

1984 • 24 citations

Did retroviruses evolve from transposable elements?

1981 • 24 citations

Demonstration of an S1-nuclease sensitive site near the human β-globin gene, and its protection by HMG 1 and 2

1983 • 23 citations

An unusual accumulation of repetitive sequences in the rat genome

1983 • 17 citations

The garden path

1982 • 16 citations

Conformation of DNA in chromatin reconstituted from poly [d(A-T)] and the core histones

1981 • 14 citations

Genetics: DNA hybridization — beware

1984 • 10 citations

A comparison of the promoter strengths of two eukaryotic genesin vitroreveals a region of DNA that can influence the rate of transcription in cis over long distances

1983 • 8 citations

Studies on synthetic chromatins containing poly(dA-dT)·poly(dA-dT) and poly(dG-dC)·poly(dG-dC)

1983 • 7 citations