Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a Murine tumor model

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Nonparametric Estimation from Incomplete Observations

1958 • 7,673 citations

Current protocols in molecular biology

1988 • 7,584 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

Nonreplicating vaccinia vector efficiently expresses recombinant genes.

1992 • 598 citations

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.

1982 • 506 citations

A soluble receptor for interleukin-1β encoded by vaccinia virus: A novel mechanism of virus modulation of the host response to infection

1992 • 475 citations

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species soecificity

1995 • 474 citations

Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence

1991 • 470 citations

Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein

1991 • 334 citations

Infectious poxvirus vectors have capacity for at least 25 000 base pairs of foreign DNA

1983 • 311 citations

Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara

1996 • 307 citations

Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity

1995 • 295 citations

A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus

1994 • 291 citations

Preparation of Cell Cultures and Vaccinia Virus Stocks

1998 • 278 citations

Conserved TAAATG sequence at the transcriptional and translational initiation sites of vaccinia virus late genes deduced by structural and functional analysis of the HindIII H genome fragment

1986 • 269 citations

Passage history, properties and applicability of the attenuated vaccinia virus strain MVA

1975 • 230 citations

Establishment of mouse colonic carcinoma cell lines with different metastatic properties.

1980 • 228 citations

Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection

1995 • 225 citations

Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.

1995 • 222 citations

Antitumor Activity and Immune Responses Induced by a Recombinant Carcinoembryonic Antigen-Vaccinia Virus Vaccine

1992 • 212 citations

Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7

1991 • 160 citations

Tumor antigens recognized by T lymphocytes

1997 • 153 citations

Temporal regulation of influenza hemagglutinin expression in vaccinia virus recombinants and effects on the immune response

1986 • 149 citations

Immunization with a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: long-term protection and effect of revaccination

1988 • 133 citations

Host Range Restricted, Non-Replicating Vaccinia Virus Vectors as Vaccine Candidates

1996 • 128 citations

p53 as a target for cancer vaccines: recombinant canarypox virus vectors expressing p53 protect mice against lethal tumor cell challenge.

1996 • 123 citations

From defined human tumor antigens to effective immunization?

1995 • 118 citations

IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases.

1995 • 117 citations

Fowlpox Virus Host Range Restriction: Gene Expression, DNA Replication, and Morphogenesis in Nonpermissive Mammalian Cells

1993 • 113 citations

Viroceptors, virokines and related immune modulators encoded by DNA viruses

1995 • 112 citations

Tumour prevention and rejection with recombinant vaccinia

1987 • 101 citations

Recombinant vaccinia virus vaccine against the human melanoma antigen p97 for use in immunotherapy.

1988 • 98 citations

Vaccination with two different vaccinia recombinant viruses: long-term inhibition of secondary vaccination

1993 • 93 citations

Vaccinia virus glycoproteins and immune evasion: The Sixteenth Fleming Lecture

1993 • 75 citations

Pillars Article: Cytotoxic T-cell Memory without Antigen. Nature. 1994. 369: 648-652.

2013 • 63 citations

[Experiences with immunization against orthopox viruses of humans and animals using vaccine strain MVA].

1994 • 49 citations

The development of new cancer therapies based on the molecular identification of cancer regression antigens.

1995 • 44 citations

Virological evidence for the success of the smallpox eradication programme

1979 • 44 citations

Determination of the promoter region of an early vaccinia virus gene encoding thymidine kinase

1987 • 42 citations

Synthetic oligonucleotide expressed by a recombinant vaccinia virus elicits therapeutic CTL.

1995 • 42 citations

Metastatic conversion of cells by expression of human papillomavirus type 16 E6 and E7 genes.

1993 • 29 citations

Anti-Tumor Activity of Cytotoxic T Lymphocytes Elicited with Recombinant and Synthetic Forms of a Model Tumor-Associated Antigen

1995 • 27 citations

Potential Antigenic Targets on Epstein ‐ Barr Virus‐Associated Tumours and the Host Response

2007 • 13 citations

Vaccines against virally induced cancers

1994 • 13 citations

Hepatitis B Virus Infection, the Immune Response and Hepatocellular Carcinoma

2007 • 10 citations

Strategies for Studying Mouse and Human Immune Responses to Human Papillomavirus Type 16

2007 • 10 citations

The role of antigen in maintaining T cell memory.

1994 • 9 citations

Human T Cell Lymphotropic Virus: Necessity for and Feasibility of a Vaccine

2007 • 3 citations