Host Range Restricted, Non-Replicating Vaccinia Virus Vectors as Vaccine Candidates

Smallpox and its eradication

1988 • 1,387 citations

Smallpox and its eradication

1989 • 1,365 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

Vaccinia virus: a selectable eukaryotic cloning and expression vector.

1982 • 663 citations

General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes

1984 • 652 citations

Nonreplicating vaccinia vector efficiently expresses recombinant genes.

1992 • 598 citations

Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

1985 • 526 citations

Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.

1982 • 506 citations

NYVAC: A highly attenuated strain of vaccinia virus

1992 • 473 citations

Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence

1991 • 470 citations

Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype

1985 • 447 citations

Vaccinia Virus: A Tool for Research and Vaccine Development

1991 • 410 citations

Protection of Macaques Against SIV Infection by Subunit Vaccines of SIV Envelope Glycoprotein gp160

1992 • 340 citations

Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein

1991 • 334 citations

[The smallpox vaccination strain MVA: marker, genetic structure, experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism (author's transl)].

1978 • 308 citations

A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus

1994 • 291 citations

Deletion of the vaccinia virus growth factor gene reduces virus virulence

1988 • 238 citations

Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells

1984 • 234 citations

Passage history, properties and applicability of the attenuated vaccinia virus strain MVA

1975 • 230 citations

Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.

1995 • 222 citations

Prevention of vaccinia virus infection in imiminodeficient mice by vector-directed IL-2 expression

1987 • 216 citations

MVA-Stufenimpfung gegen Pocken

1974 • 209 citations

Recovery of immunodeficient mice from a vaccinia virus/IL-2 recombinant infection

1987 • 198 citations

MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA).

1974 • 178 citations

Nonreplicating viral vectors as potential vaccines: Recombinant canarypox virus expressing measles virus fusion (F) and hemagglutinin (HA) glycoproteins

1992 • 154 citations

IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases.

1995 • 117 citations

Cell-mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinants

1986 • 83 citations

Immune response of rhesus macaques to recombinant simian immunodeficiency virus gp130 does not protect from challenge infection

1993 • 77 citations

Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines

1994 • 64 citations

Studies on poxvirus infections in irradiated animals

1980 • 43 citations

Immunization with whole inactivated vaccine protects from infection by SIV grown in human but not macaque cells

1994 • 35 citations

Genetic Variation of Simian Immunodeficiency Viruses in Nonhuman Primates

1992 • 27 citations

Inactivated Whole SIV Vaccine in Macaques: Evaluation of Protective Efficacy Against Challenge with Cell-Free Virus or Infected Cells

1992 • 27 citations

[Virulence and immunogenicity of a modified vaccinia virus (strain MVA) (author's transl)].

1972 • 14 citations

[Significance of animal pox for man following elimination of compulsory vaccination against smallpox].

1979 • 6 citations

Deleted Work

1955 • 0 citations