Cytokines in viral diseases

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins

1990 • 977 citations

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

1991 • 752 citations

Infection with HIV is associated with elevated IL-6 levels and production.

1990 • 594 citations

Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1

1990 • 539 citations

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.

1990 • 529 citations

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression.

1990 • 471 citations

Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

1991 • 406 citations

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor

1989 • 331 citations

Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV.

1989 • 314 citations

Immunopathogenic mechanisms of HIV infection: cytokine induction of HIV expression

1990 • 290 citations

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes.

1990 • 237 citations

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

1990 • 229 citations

Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection.

1990 • 194 citations

Transforming growth factor beta suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage.

1991 • 162 citations

The chemotactic activity for granulocytes produced by virally infected fibroblasts is identical to monocyte‐derived interleukin 8

1989 • 139 citations

Immunologic Tolerance: Collaboration Between Antigen and Lymphokines

1989 • 135 citations

HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises

1989 • 126 citations

Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells

1990 • 98 citations

Activated B lymphocytes from human immunodeficiency virus-infected individuals induce virus expression in infected T cells and a promonocytic cell line, U1.

1991 • 98 citations

IL-6 production by human T lymphocytes. Expression in HTLV-1-infected but not in normal T cells.

1991 • 96 citations

Simultaneous production of interleukin 6, interferon‐β and colony‐stimulating activity by fibroblasts after viral and bacterial infection

1989 • 90 citations

Cytomegalovirus infection stimulates expression of monocyte-associated mediator genes.

1989 • 89 citations

Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis

1991 • 81 citations

trans activation of granulocyte-macrophage colony-stimulating factor and the interleukin-2 receptor in transgenic mice carrying the human T-lymphotropic virus type 1 tax gene.

1989 • 80 citations

Cytotoxic T Lymphocyte Control of Acute Lymphocytic Choriomeningitis Virus Infection: Interferon , but Not Tumour Necrosis Factor , Displays Antiviral Activity in vivo

1989 • 72 citations

Lymphotoxin activation by human T-cell leukemia virus type I-infected cell lines: role for NF-kappa B

1990 • 71 citations

Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus‐infected mice with anti‐interferon‐γ monoclonal antibody blocks generation of virus‐specific cytotoxic T lymphocytes and virus elimination

1989 • 71 citations

Human immunodeficiency virus-1 infection of macrophages in vitro neither induces tumor necrosis factor (TNF)/cachectin gene expression nor alters TNF/cachectin induction by lipopolysaccharide.

1990 • 68 citations

T-cell activation is required for efficient replication of human herpesvirus 6

1990 • 59 citations

Protein kinase regulates tumor necrosis factor mRNA stability in virus-stimulated astrocytes.

1990 • 56 citations

MINIREVIEW: Cytokines: An Expanding Network of Immuno-lnflammatory Hormones

1988 • 54 citations

RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2.

1990 • 52 citations

HTLV-1 p27rex stabilizes human interleukin-2 receptor alpha chain mRNA.

1990 • 47 citations

Modulation of interleukin-1 beta RNA in monocytic cells infected with human immunodeficiency virus-1.

1990 • 30 citations

Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon

1991 • 29 citations