Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

The biology of interleukin-6

1989 • 1,964 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

Isolation of a New Human Retrovirus from West African Patients with AIDS

1986 • 1,260 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Correlations and interactions in the production of interleukin-6 (IL- 6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF

1990 • 991 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes.

1988 • 785 citations

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1988 • 739 citations

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

1989 • 726 citations

Monocytes and Macrophages

1988 • 711 citations

Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes.

1987 • 426 citations

Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes.

1978 • 379 citations

Neutralization of the AIDS Retrovirus by Antibodies to a Recombinant Envelope Glycoprotein

1986 • 362 citations

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor

1989 • 331 citations

Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV.

1989 • 314 citations

Production of lymphocyte-activating factor (Interleukin 1) by macrophages activated with colony-stimulating factors.

1980 • 272 citations

Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1.

1989 • 270 citations

Stimulation of murine hemopoietic colony formation by human IL-6.

1988 • 237 citations

Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). Monocyte-tropic and lymphocyte-tropic strains of HIV-1 show distinctive patterns of replication in a panel of cell types.

1989 • 217 citations

Cell classification by laser light scattering: identification and separation of unstained leukocytes.

1975 • 204 citations

Spontaneous cytotoxicity and tumor necrosis factor production by peripheral blood monocytes from AIDS patients.

1988 • 187 citations

Tumor necrosis factor induction by Sendai virus.

1986 • 177 citations

Measurement of immunoreactive interleukin-1β from human mononuclear cells: Optimization of recovery, intrasubject consistency, and comparison with interleukin-1α and tumor necrosis factor

1988 • 173 citations

Concentrations of Immunoreactive Human Tumor Necrosis Factor Alpha Produced by Human Mononuclear Cells In Vitro

1988 • 172 citations

Transcriptional regulation of the human prointerleukin 1 beta gene.

1987 • 172 citations

Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus.

1989 • 172 citations

Purified blood monocytes from HIV 1-infected patients induce high levels of TNFα and IL-1

1989 • 165 citations

Interleukin 1 and interleukin 1 inhibitor production by human macrophages exposed to influenza virus or respiratory syncytial virus. Respiratory syncytial virus is a potent inducer of inhibitor activity.

1986 • 161 citations

Polymyxin-B inhibition of LPS-induced interleukin-1 secretion by human monocytes is dependent upon the LPS origin

1986 • 104 citations

Human T-lymphotropic virus I-infected T cells constitutively express lymphotoxin in vitro

1989 • 99 citations

Viral antigen stimulation of the production of human monokines capable of regulating HIV1 expression.

1989 • 96 citations

Idiopathic production of interleukin-1 in acquired immune deficiency syndrome

1987 • 91 citations

Interleukin 1 inhibitor masks high interleukin 1 production in acquired immunodeficiency syndrome (AIDS)

1987 • 79 citations

Human Monocyte Production of Interleukin-1: Parameters of the Induction of Interleukin-1 Secretion by Lipopolysaccharides

1986 • 78 citations

A method for removing interleukin-1- and tumor necrosis factor-inducing substances from bacterial cultures by ultrafiltration with polysulfone

1989 • 62 citations

Characterization of Serum Netralization Response to the Human Immunodeficiency Virus (HIV)

1987 • 55 citations

Absence of induction of IL-1 production in human monocytes by complement fragments.

1989 • 49 citations

Interleukin 1 production by the human monocyte cell line U937 requires a lymphokine induction signal distinct from interleukin 2 or interferons.

1985 • 44 citations

Use of a Sensitive Neutralization Assay to Measure the Prevalence of Antibodies to the Human Immunodeficiency Virus

1988 • 38 citations

Recognition of HIV glycoprotein gp120 by T cells. Role of monocyte CD4 in the presentation of gp120.

1989 • 24 citations